Evaluation of Thermal Variations of Irrigation on the Osseointegration of Dental Implants: An In vivo Study in Rabbit Models.

Doğukan Yılmaz; Halit Furuncuoğlu; Osman Varol; Hakan Akın

doi:10.7126/cumudj.669313

EN

Evaluation of Thermal Variations of Irrigation on the Osseointegration of Dental Implants: An In vivo Study in Rabbit Models.

Abstract

Objectives: Thermal trauma during implant surgery limits the proper healing process. The aim of the study was to investigate the effect of different irrigation temperatures during implant surgery on the osseointegration of dental implants. Materials and Methods: Eight adult male New Zealand white rabbits were used in this study. Total of 32 implants were inserted in each tibia of each rabbit’s rear legs. Rabbits were randomly divided according to different irrigation procedures applied (37°C, 24°C, 10°C, and 1°C). Resonance frequency analysis (RFA) was performed following to implant surgery, 1th week, 2nd week, 3rd week, and 1th month. In addition, removal torque values (RTVs) were measured from sacrificed tibias at the end of 30 days. Results: No significant difference in implant stability quotient (ISQ) was detected between groups from the first measurement to 5th measurement. However, there was a statistically significant difference in RTVs between 1°C and 37°C, and 1°C and 10°C (p=0.024 and p=0.013, respectively). Conclusion: Different irrigation temperatures during implant surgery were not effective on the primary and secondary stability values of dental implants in rabbit models.

Keywords

Dental Implant,Osseointegration,Trauma,Rabbit Model

Supporting Institution

Cumhuriyet Üniversitesi

Project Number

DİŞ-168

References

1.Albrektsson T, Lekholm U. Osseointegration: current state of the art. Dent Clin North Am 1989;33:537.
2.Sutter F, Krekeler G, Schwammberger AE, Sutter FJ. Atraumatic surgical technique and implant bed preparation. Quintessence Int 1992;23:811-816.
3.Flanagan D. Heat generated during seating of dental implant fixtures. J Oral Implantol 2014;40:174-181
4.Scarano A, Piattelli A, Assenza B, Carinci F, Di Donato L, Romani GL, Merla A. Infrared thermographic evaluation of temperature modifications induced during implant site preparation with cylindrical versus conical drills. Clin Implant Dent Relat Res 2011;13:319-323.
5.Carvalho AC, Queiroz TP, Okamoto R, Margonar R, Garcia IR Jr, Magro Filho O. Evaluation of bone heating, immediate bone cell viability, and wear of high-resistance drills after the creation of implant osteotomies in rabbit tibias. Int J Oral Maxillofac Implants 2011; 26:1193-1201.
6.Eriksson RA, Albrektsson T. The effect of heat on bone regeneration: an experimental study in the rabbit using the bone growth chamber. J Oral Maxillofac Surg 1984;42: 705-711.
7.Tehemar SH. Factors affecting heat generation during implant site preparation: a review of biologic observations and future considerations. Int J Oral Maxillofac Implants 1999;14:127-136.
8.Yoshida K, Uoshima K, Oda K, Maeda T. Influence of heat stress to matrix on bone formation. Clin Oral Implants Res 2009;20:782-790.

9.Strbac GD, Giannis K, Unger E, Mittlböck M, Vasak C, Watzek G, Zechner W. Drilling and withdrawing related thermal changes during implant site osteotomies. Clin Implant Dent Relat Res 2015;17:32-43.
10.Kim SJ, Yoo J, Kim YS, Shin SW. Temperature change in pig rib bone during implant site preparation by low-speed drilling. J Appl Oral Sci 2010;18:522-527.
11.Kondo S, Okada Y, Iseki H, Hori T, Takakura K, Kobayashi A, Nagata H. Thermological study of drilling bone tissue with a high-speed drill. Neurosurg 2000;46:1162-1168.
12.Hochscheidt CJ, Shimizu RH, Andrighetto AR, Moura LM, Golin AL, Hochscheidt RC. Thermal variation during osteotomy with different dental implant drills: a standardized study in bovine ribs. Implant Dent 2017;26:73-79.
13.El-Kholey KE, Ramasamy S, Kumar RS, Elkomy A. Effect of simplifying drilling technique on heat generation during osteotomy preparation for dental implant. Implant Dent 2017;26:888-891.
14.El-Kholey KE, Elkomy A. Effect of the drilling technique on heat generation during osteotomy preparation for wide diameter implants. Implant Dent 2016;25:825-828.
15.Trisi P, Berardini M, Falco A, Vulpiani MP. Effect of temperature on the dental implant osseointegration development in low-density bone: an in vivo histological evaluation. Implant Dent 2015;24:96-100.
16.Gehrke SA, Aramburú Júnior JS, Pérez-Albacete Martínez C, Ramirez Fernandez MP, Maté Sánchez de Val JE, Calvo-Guirado JL. The influence of drill length and irrigation system on heat production during osteotomy preparation for dental implants: an ex vivo study. Clin Oral Implants Res 2018;29:772-778.
17.Strbac GD, Giannis K, Unger E, Mittlböck M, Watzek G, Zechner W. A novel standardized bone model for thermal evaluation of bone osteotomies with various irrigation methods. Clin Oral Implants Res 2014;25:622-631.
18.Gehrke SA, Loffredo NH, Mardegan FE. Investigation of the effect of movement and irrigation systems on temperature in the conventional drilling of cortical bone. Br J Oral Maxillofac Surg 2013;51:953-957.
19.Gehrke SA, Pazetto MK, de Oliveira S, Corbella S, Taschieri S, Mardegan FE. Study of temperature variation in cortical bone during osteotomies with trephine drills. Clin Oral Investig 2014;18:1749-1755.
20.Benington IC, Biagioni PA, Briggs J, Sheridan S, Lamey PJ. Thermal changes observed at implant sites during internal and external irrigation. Clin Oral Implants Res 2002;13:293-297.
21.Sindel A, Dereci Ö, Hatipoğlu M, Altay MA, Özalp Ö, Öztürk A. The effects of irrigation volume to the heat generation during implant surgery. Med Oral Patol Oral Cir Bucal 2017;22:506-511.
22.Rashad A, Kaiser A, Prochnow N, Schmitz I, Hoffmann E, Maurer P. Heat production during different ultrasonic and conventional osteotomy preparations for dental implants. Clin Oral Implants Res 2011;22:1361-1365.
23.Sannino G, Gherlone EF. Thermal changes during guided flapless implant site preparation: a comparative study. Int J Oral Maxillofac Implants 2018;33:671-677.
24.Sener BC, Dergin G, Gursoy B, Kelesoglu E, Slih I. Effects of irrigation temperature on heat control in vitro at different drilling depths. Clin Oral Implants Res 2009;20:294-298.
25.Pearce AI, Richards RG, Milz S, Schneider E, Pearce SG. Animal models for implant biomaterial research in bone: a review. Eur Cell Mater 2007;13:1-10.
27.Sul YT, Johansson CB, Albrektsson T. Oxidized titanium screws coated with calcium ions and their performance in rabbit bone. Int J Oral Maxillofac Implants 2002;17:625-634.
28.Möhlhenrich SC, Modabber A, Steiner T, Mitchell DA, Hölzle F. Heat generation and drill wear during dental implant site preparation: systematic review. Br J Oral Maxillofac Surg 2015;53:679-689.
29.Möhlhenrich SC, Abouridouane M, Heussen N, Modabber A, Klocke F, Hölzle F. Influence of bone density and implant drill diameter on the resulting axial force and temperature development in implant burs and artificial bone: an in vitro study. Oral Maxillofac Surg 2016;20:135-142.
30.Shah FA, Thomsen P, Palmquist A. A review of the impact of implant biomaterials on osteocytes. J Dent Res 2018;97:977-986.
31. Barrak I, Boa K, Joób-Fancsaly Á, Varga E, Sculean A, Piffko J. Heat Generation During Guided and Freehand Implant Site Preparation at Drilling Speeds of 1500 and 2000 RPM at Different Irrigation Temperatures: An In Vitro Study. Oral Health Prev Dent 2019; 9:1-8
32.Ota T, Nishida Y, Ikuta K, Kato R, Kozawa E, Hamada S, Sakai T, Ishiguro N. Heat-stimuli enhanced osteogenesis using clinically available biomaterials. PLoS One 2017;18:12.
33.Chen E, Xue D, Zhang W, Lin F, Pan Z. Extracellular heat shock protein 70 promotes osteogenesis of human mesenchymal stem cells through activation of the ERK signaling pathway. FEBS Lett 2015;21:589:4088-4096.
34.Meredith N, Shagaldi F, Alleyne D, Sennerby L, Cawley P. The application of resonance frequency measurements to study the stability of titanium implants during healing in the rabbit tibia. Clin Oral Implants Res 1997;8:234-243.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Doğukan Yılmaz ^*
0000-0003-2576-0885
Türkiye

Halit Furuncuoğlu
0000-0002-2093-4121
Türkiye

Osman Varol
0000-0002-9775-4954
Türkiye

Hakan Akın
0000-0002-4770-4297
Türkiye

Publication Date

March 18, 2020

Submission Date

January 2, 2020

Acceptance Date

March 9, 2020

Published in Issue

Year 1970 Volume: 23 Number: 1

DOI

https://doi.org/10.7126/cumudj.669313

IZ

https://izlik.org/JA88BM28GN

Cite

RIS / Bibtex

EndNote

Yılmaz D, Furuncuoğlu H, Varol O, Akın H (March 1, 2020) Evaluation of Thermal Variations of Irrigation on the Osseointegration of Dental Implants: An In vivo Study in Rabbit Models. Cumhuriyet Dental Journal 23 1 52–59.

Cited By

Non-Destructive Removal of Dental Implant by Cryogenic Method

Medicina

https://doi.org/10.3390/medicina58070849

Evaluation of the surface thermal response of peripheral nerve blocks in dogs undergoing trauma or orthopedic surgery

Frontiers in Veterinary Science

https://doi.org/10.3389/fvets.2025.1640338

Öz

Evaluation of Thermal Variations of Irrigation on the Osseointegration of Dental Implants: An In vivo Study in Rabbit Models.

Abstract

Keywords

Supporting Institution

Project Number

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Non-Destructive Removal of Dental Implant by Cryogenic Method

Evaluation of the surface thermal response of peripheral nerve blocks in dogs undergoing trauma or orthopedic surgery