Periodontitis is an inflammatory condition of the periodontium leading to loss of supporting structures of the tooth. The regeneration of periodontium refers to the restoration of the lost tissues to their original form and function by reiterating the fundamental wound healing processes involved in their development. Research has led to the development of “Autologous biomaterials” provide signals for healing, repair, and regeneration. These autologous substances also fosters neo-angiogenesis and new bone formation and therefore have yielded encouraging results in the field of regenerative dentistry.
Platelet concentrates have higher concentration of growth factors which enhance periodontal regeneration. Blood derivatives have several advantages such as being autogenous, cost effective, less time consuming, simple to perform and prolonged release of growth factors. Since inception, many approaches have evolved also in-depth research has been done regarding its biological and clinical applications. Several modifications have been advocated in the conventional protocol like the advanced PRF, injectable PRF, PRF lysate and Titanium-prepared PRF.
This review paper addresses the evolution, applications of platelet concentrates for tissue engineering, recent advances, and novel protocols. Furthermore, several future perspectives of platelet concentrates, such as platelet concentrates as drug delivery agents, platelet dust and liposomes encapsulating platelet concentrates are also discussed.
Autologous biomaterials Periodontal Regeneration Platelet concentrates Platelet rich Fibrin.
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Review |
Yazarlar | |
Yayımlanma Tarihi | 23 Haziran 2023 |
Gönderilme Tarihi | 10 Haziran 2022 |
Yayımlandığı Sayı | Yıl 2023Cilt: 26 Sayı: 2 |
Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.
CDJ accepts articles in English. Submitting a paper to CDJ is free of charges. In addition, CDJ has not have article processing charges.
Frequency: Four times a year (March, June, September, and December)
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