Abstract
Objectives: Implants are the natural or artificial
materials that replace a missing tissue or organ. When that missing part is one
or more teeth, there is a need for the reconstructive material that supports
prosthetic restoration, which is called dental implant. Many local and general
factors affect bone healing. Recent studies show that, free radicals are among
the factors that affect the bone healing. This study is planned presuming
propolis could have positive effects on oxidative stress and bone healing after
implantation due to its antioxidant nature, its effects on accelerating the
bone formation, wound healing and increasing the bone density.
Materials
and Methods: 24 New
Zealand white rabbits were used in the study. Animals were divided into 3
groups, each consisting of 8 rabbits. Implants were placed into the proximal
region of tibia unilaterally. Propolis was applied to slots before placing the
implants on local group and systemically applied after implantation on systemic
group.
Results: SOD activity was increased in both propolis groups
compared to control group, but it was not statistically significant. Catalase
level of the systemic group was found to be significantly higher. MDA level in
serum, which indicates lipid peroxidation, was significantly lower in both
propolis groups compared to control group. Reduced GSH concentration in
granulation tissue was increased in rabbit groups treated with propolis
compared to control group. There were no significant differences in calcium and
phosphorus values, however it can be said that there is a significant increase
in vitamin D amount of local and systemic groups.
Conclusion: Propolis has antioxidant, antimicrobial and many other
biological activities. Due to the features that it has, propolis has a positive
effect on osseointegration and bone healing. The comparison of systemic and
local group showed that, systemically given propolis provided better results
than local application.
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Original Research Articles |
Yazarlar | |
Yayımlanma Tarihi | 20 Temmuz 2018 |
Gönderilme Tarihi | 20 Kasım 2017 |
Yayımlandığı Sayı | Yıl 2018Volume: 21 Issue: 2 |
Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.
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