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THE ROLE OF STATINS IN PERIODONTAL THERAPY – A REVIEW

Year 2022, Volume: 25 Issue: 2, 200 - 205, 30.06.2022
https://doi.org/10.7126/cumudj.1006424

Abstract

Periodontitis is an inflammatory mechanism causing step by step destruction of the periodontal tissues and alveolar bone. Periodontal treatment is intended to restore the tissues damaged by the disease. Various periodontal procedures have been introduced to lower the destruction; statins are being one among them. They are cholesterol-reducing drugs which have shown to promote bone formation and proven to be effective in periodontal therapy. However, statins have numerous actions, with anti-inflammatory and immunomodulatory effects, as well as the capacity to accelerate new bone formation. The pleiotropic effects of statins have been assessed for their prospective advantage in the therapy of several inflammatory and immune-mediated diseases including periodontitis. Such features could be beneficial for periodontal therapies. This article goes through the history and effects of statins and explores its potential role in periodontal regenerative therapy.

References

  • Goodson JM, Cugini MA, Kent RL, Armitage GC, Cobb CM, Fine D, et al. Multicenter evaluation of tetracycline fiber therapy: I. Experimental design, methods, and baseline data. J Periodont Res 1991a; 26:361-70.
Year 2022, Volume: 25 Issue: 2, 200 - 205, 30.06.2022
https://doi.org/10.7126/cumudj.1006424

Abstract

References

  • Goodson JM, Cugini MA, Kent RL, Armitage GC, Cobb CM, Fine D, et al. Multicenter evaluation of tetracycline fiber therapy: I. Experimental design, methods, and baseline data. J Periodont Res 1991a; 26:361-70.
There are 1 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Review
Authors

Anjale Rajagopal 0000-0002-7232-1570

Meena Anand 0000-0002-7501-6635

Publication Date June 30, 2022
Submission Date October 8, 2021
Published in Issue Year 2022Volume: 25 Issue: 2

Cite

EndNote Rajagopal A, Anand M (June 1, 2022) THE ROLE OF STATINS IN PERIODONTAL THERAPY – A REVIEW. Cumhuriyet Dental Journal 25 2 200–205.

Cited By

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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