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TEMPOROMANDIBULAR JOINT DISEASE AND VITAMIN D LEVEL IN FIBROMYALGIA

Year 2022, Volume: 25 Issue: Supplement, 29 - 33, 25.03.2022

Samed Şatır , Özlem Şatır

https://doi.org/10.7126/cumudj.1030953

Abstract

Objectives: The aim of our study is to show the prevalence of temporomandibular joint disease (TMD) in fibromyalgia (FM) patients in Turkish population and to evaluate the relationship between vitamin D levels of FM patients with TMD.
Materials and Methods: Patients diagnosed FM in the last 4 months were examined in terms of TMD using DC/TMD criteria. By using biochemical data of the patients included in the study, the relationship between vitamin D levels and TMD was interpreted.
Results: Among the 39 patients who underwent temporomandibular joint examination (mean age 39,8; age range 18-59), the number of patients with TMD (muscle pain, joint pain, mouth opening limitation, disc displacement, degenerative joint disease) was 30 (29 female, 1 male), while the number of patients without any TMD was found 9 (7 female, 2 male). No statistically significant difference was found between those with TMD and those without TMD in terms of vitamin D (Mann-Whitney U test, D vit p=0,257).
Conclusions: Dentists should be aware that patients with widespread pain in the temporomandibular joint area may be candidates for FM and should be careful in evaluating laboratory tests of these patients. The prevalence of TMJ in FM patients and its relationship with vitamin D should be examined with new studies with large patient participation.

Öz
Amaç: Çalışmamızın amacı, Türk toplumunda fibromyalji (FM) hastalarındaki temporomandibular eklem hastalık (TMEH) prevelensını göstermek ve FM hastalarına ait D vitamini seviyelerinin TMEH ile ilişkisini değerlendirmektir.
Gereç ve Yöntemler: Son 4 ay içerisinde FM teşhisi konmuş hastalar DC/TMD kriterleri kullanılarak TMEH açısından incelenmiştir. Yapılan muayene ile masseter ve temporal kasta ağrı, eklem ağrısı, redüksiyonlu/ redüksiyonsuz disk deplasmanı, dejeneratif eklem hastalığı sorgulanmıştır. Çalışmaya dahil edilen hastaların biyokimya verileri kullanılarak D vitamini seviyelerinin TMEH ile ilişkisi yorumlanmıştır.
Bulgular: Temporomandibular eklem muayenesi yapılan toplam 39 FM hastasından (yaş ortalaması 39,8; yaş aralığı 18-59) 36’sı kadın 3’ü ise erkektir. Tüm hastalar içerisinde TMEH tespit edilenlerin sayısı 30 (29 kadın, 1 erkek) iken, herhangi bir TMEH bulgusuna rastlanmayan hastaların sayısı 9 (7 kadın, 2 erkek)’dur. TMEH tespit edilen hastaların 26’sında kas ağrısı gözlenmiştir. Kas ağrısı görülmeksizin eklem ağrısı ve dejeneratif eklem hastalığı bulunan sırasıyla 2 ve 1 hasta tespit edilmiştir. TMEH varlığı olanların D vitamini değerleri TMEH varlığı olmayanlara göre düşük olmasına rağmen istatistiksel olarak anlamlı bir farklılık bulunamamıştır (Mann-Whitney U test, p=0,257).
Sonuçlar: Diş hekimleri özellikle temporomandibular eklem bölgesinde yaygın ağrı şikâyeti olan hastaların FM hastası adayı olabileceğinin farkında olmalı ve bu hastaların laboratuvar testlerini değerlendirme konusunda dikkatli olmalıdır. Geniş hasta katılımı ile yapılacak yeni çalışmalar ile FM hastalarındaki TMEH prevalansının D vitamini ile olan ilişkisi incelenmelidir.
Anahtar Kelimeler: Fibromyalji, Temporomandibular Eklem, D Vitamini

Keywords

Fibromyalgia Temporomandibular Joint Vitamin D

References

  • 1. Kia S, Choy E. Update on treatment guideline in fibromyalgia syndrome with focus on pharmacology. The Biomedicines 2017;5(20): doi:10.3390/biomedicines5020020.
  • 2. Gür A. Fibromiyaljide etiyopatogenez. Türk Fiz Tıp Rehab Derg. 2008;54(Özel Sayı 1):4-11.
  • 3. Fitzcharles MA, Ste-Marie PA, Goldenberg DL, Pereira JX, Abbey S, Choinière M et al. National Fibromyalgia Guideline Advisory Panel. 2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: executive summary. Pain Res Manag. 2013 May-Jun;18(3):119-26.
  • 4. Heymann RE, Paiva ES, Martinez JE, Helfenstein M Jr, Rezende MC, Provenza JR et al. New guidelines for the diagnosis of fibromyalgia. Rev Bras Reumatol Engl Ed. 2017;57 Suppl 2:467-476.
  • 5. Durham J, Newton-John TR, Zakrzewska JM. Temporomandibular disorders. BMJ. 2015 Mar 12;350:h1154.
  • 6. Pimentel MJ, Gui MS, Martins de Aquino LM, Rizzatti-Barbosa CM. Features of temporomandibular disorders in fibromyalgia syndrome. Cranio. 2013 Jan;31(1):40-5.
  • 7. Rhodus NL, Fricton J, Carlson P, Messner R. Oral symptoms associated with fibromyalgia syndrome. J Rheumatol. 2003 Aug;30(8):1841-5.
  • 8. Palinkas M, Bataglion C, de Luca Canto G, Machado Camolezi N, Theodoro GT, Siéssere S et al. Impact of sleep bruxism on masseter and temporalis muscles and bite force. Cranio. 2016 Sep;34(5):309-15.
  • 9. Karahan AY, Kaya B, Kuran B, Altindag O, Yildirim P, Dogan SC, et al. Common Mistakes in the Dual-Energy X-ray Absorptiometry (DXA) in Turkey. A Retrospective Descriptive Multicenter Study. Acta medica (Hradec Kralove) 2016; 59:117-23.
  • 10. Mavromati M, Philippe J. [Endocrinology, what’s new in 2016]. Rev Med Suisse 2017; 13:45-8.
  • 11. Yagiz AE, Ustun N, Paksoy H, Ustun I, Mansuroglu A, Guler H, et al. Association of Vitamin D with Disease Activity in Rheumatoid Arthritis and Ankylosing Spondylitis. J Clin Anal Med 2015; 6:486-9.
  • 12. Brouwer-Brolsma EM, Vaes AMM, van der Zwaluw NL, van Wijngaarden JP, Swart KMA, Ham AC, et al. Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochemy Mol Biol 2016; 164:168-76.
  • 13. Colak S, Aydogan BI, Gokcay Canpolat A, Tulunay Kaya C, Sahin M, Corapcioglu D et al. Is primary hyperparathyroidism a cause of endothelial dysfunction? Clin Endocrinol (Oxf) 2017; 87:459-65.
  • 14. Fidan F, Alkan BM, Tosun A. Çağın pandemisi: D vitamini eksikliği ve yetersizliği. Turk J Osteoporos 2014; 20:71-4.
  • 15. Cerit Z. Vitamin D, body composition, and epicardial adipose tissue. Clin Nutr 2017; 36:1450.
  • 16. Dogru A, Balkarli A, Cobankara V, Tunc SE, Sahin M. Effects of Vitamin D Therapy on Quality of Life in Patients with Fibromyalgia. Eurasian J Med 2017; 49:113-7.
  • 17. Sugiyama T. Vitamin D and bone health: interpreting observational studies. J Intern Med 2017; 282:272-3.
  • 18. Tonnesen R, Hovind PH, Jensen LT, Schwarz P. Determinants of vitamin D status in young adults: influence of lifestyle, sociodemographic and anthropometric factors. BMC Public Health 2016; 16:385.
  • 19. Hightower JM, Dalessandri KM, Pope K, Hernandez GT. Low 25-Hydroxyvitamin D and Myofascial Pain: Association of Cancer, Colon Polyps, and Tendon Rupture. J Am Coll Nutr 2017; 36:455-61.
  • 20. Batista ED, Andretta A, de Miranda RC, Nehring J, Dos Santos Paiva E, Schieferdecker ME. Food intake assessment and quality of life in women with fibromyalgia. Rev Bras Reumatol Engl Ed. 2016 Mar-Apr;56(2):105-10.
  • 21. de Carvalho JF, Silva DN. Serum levels of vitamin B12 (cobalamin) in fibromyalgia. Rheumatol Int. 2016 May;36(5):741-2.
  • 22. Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP et al. International RDC/TMD Consortium Network, International association for Dental Research; Orofacial Pain Special Interest Group, International Association for the Study of Pain. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache. 2014 Winter;28(1):6-27.
  • 23. Ayouni I, Chebbi R, Hela Z, Dhidah M. Comorbidity between fibromyalgia and temporomandibular disorders: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jul;128(1):33-42.
  • 24. Gui MS, Pedroni CR, Aquino LM, Pimentel MJ, Alves MC, Rossini S et al. Facial pain associated with fibromyalgia can be marked by abnormal neuromuscular control: a cross-sectional study. Phys Ther. 2013 Aug;93(8):1092-101.
  • 25. Fujarra FJ, Kaziyama HH, Siqueira SR, Yeng LT, Camparis CM, Teixeira MJ et al. Temporomandibular disorders in fibromyalgia patients: are there different pain onset? Arq Neuropsiquiatr. 2016 Mar;74(3):195-200.
  • 26. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.
  • 27. Makrani AH, Afshari M, Ghajar M, Forooghi Z, Moosazadeh M. Vitamin D and fibromyalgia: a meta-analysis. Korean J Pain. 2017 Oct;30(4):250-257.
  • 28. McBeth J, Pye SR, O’Neill TW, Macfarlane GJ, Tajar A, Bartfai G, et al. Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study. Ann Rheum Dis 2010; 69:1448-52.
  • 29. Olama SM, Senna MK, Elarman MM, Elhawary G. Serum vitamin D level and bone mineral density in premenopausal Egyptian women with fibromyalgia. Rheumatol Int 2013; 33: 185-92.
  • 30. Karahan AY, Hüner B, Kuran B, Sezer N, Çelik C, Salbaş E et al. Vitamin D Düzeyi ile Non-spesifik Kas İskelet Sistemi Ağrıları Arasındaki İlişkinin Değerlendirilmesi: Çok Merkezli Retrospektif Bir Çalışma (İnme Çalışma Grubu). Turk J Osteoporos 2017; 23:61-66.
  • 31. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc 2003; 78:1463-70.
  • 32. Nickel JC, Iwasaki LR, Gonzalez YM, Gallo LM, Yao H. Mechanobehavior and Ontogenesis of the Temporomandibular Joint. J Dent Res. 2018 Oct;97(11):1185-1192.
  • 33. Yilmaz AD, Yazicioglu D, Tüzüner Öncül AM, Yilmaz E, Ereş G. Vitamin D receptor gene polymorphisms (Apa1 and Taq1) in temporomandibular joint internal derangement/osteoarthritis in a group of Turkish patients. Mol Biol Rep. 2018 Dec;45(6):1839-1848.
  • 34. Demir CY, Ersoz ME. Biochemical changes associated with temporomandibular disorders. J Int Med Res. 2019 Feb;47(2):765-771.
  • 35. Moreno-Fernández AM, Jiménez-Castellanos E, Iglesias-Linares A, Bueso-Madrid D, Fernández-Rodríguez A, de Miguel M. Fibromyalgia syndrome and temporomandibular disorders with muscular pain. A review. Mod Rheumatol. 2017 Mar;27(2):210-216.

Year 2022, Volume: 25 Issue: Supplement, 29 - 33, 25.03.2022

Samed Şatır , Özlem Şatır

https://doi.org/10.7126/cumudj.1030953

Abstract

References

  • 1. Kia S, Choy E. Update on treatment guideline in fibromyalgia syndrome with focus on pharmacology. The Biomedicines 2017;5(20): doi:10.3390/biomedicines5020020.
  • 2. Gür A. Fibromiyaljide etiyopatogenez. Türk Fiz Tıp Rehab Derg. 2008;54(Özel Sayı 1):4-11.
  • 3. Fitzcharles MA, Ste-Marie PA, Goldenberg DL, Pereira JX, Abbey S, Choinière M et al. National Fibromyalgia Guideline Advisory Panel. 2012 Canadian Guidelines for the diagnosis and management of fibromyalgia syndrome: executive summary. Pain Res Manag. 2013 May-Jun;18(3):119-26.
  • 4. Heymann RE, Paiva ES, Martinez JE, Helfenstein M Jr, Rezende MC, Provenza JR et al. New guidelines for the diagnosis of fibromyalgia. Rev Bras Reumatol Engl Ed. 2017;57 Suppl 2:467-476.
  • 5. Durham J, Newton-John TR, Zakrzewska JM. Temporomandibular disorders. BMJ. 2015 Mar 12;350:h1154.
  • 6. Pimentel MJ, Gui MS, Martins de Aquino LM, Rizzatti-Barbosa CM. Features of temporomandibular disorders in fibromyalgia syndrome. Cranio. 2013 Jan;31(1):40-5.
  • 7. Rhodus NL, Fricton J, Carlson P, Messner R. Oral symptoms associated with fibromyalgia syndrome. J Rheumatol. 2003 Aug;30(8):1841-5.
  • 8. Palinkas M, Bataglion C, de Luca Canto G, Machado Camolezi N, Theodoro GT, Siéssere S et al. Impact of sleep bruxism on masseter and temporalis muscles and bite force. Cranio. 2016 Sep;34(5):309-15.
  • 9. Karahan AY, Kaya B, Kuran B, Altindag O, Yildirim P, Dogan SC, et al. Common Mistakes in the Dual-Energy X-ray Absorptiometry (DXA) in Turkey. A Retrospective Descriptive Multicenter Study. Acta medica (Hradec Kralove) 2016; 59:117-23.
  • 10. Mavromati M, Philippe J. [Endocrinology, what’s new in 2016]. Rev Med Suisse 2017; 13:45-8.
  • 11. Yagiz AE, Ustun N, Paksoy H, Ustun I, Mansuroglu A, Guler H, et al. Association of Vitamin D with Disease Activity in Rheumatoid Arthritis and Ankylosing Spondylitis. J Clin Anal Med 2015; 6:486-9.
  • 12. Brouwer-Brolsma EM, Vaes AMM, van der Zwaluw NL, van Wijngaarden JP, Swart KMA, Ham AC, et al. Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study. J Steroid Biochemy Mol Biol 2016; 164:168-76.
  • 13. Colak S, Aydogan BI, Gokcay Canpolat A, Tulunay Kaya C, Sahin M, Corapcioglu D et al. Is primary hyperparathyroidism a cause of endothelial dysfunction? Clin Endocrinol (Oxf) 2017; 87:459-65.
  • 14. Fidan F, Alkan BM, Tosun A. Çağın pandemisi: D vitamini eksikliği ve yetersizliği. Turk J Osteoporos 2014; 20:71-4.
  • 15. Cerit Z. Vitamin D, body composition, and epicardial adipose tissue. Clin Nutr 2017; 36:1450.
  • 16. Dogru A, Balkarli A, Cobankara V, Tunc SE, Sahin M. Effects of Vitamin D Therapy on Quality of Life in Patients with Fibromyalgia. Eurasian J Med 2017; 49:113-7.
  • 17. Sugiyama T. Vitamin D and bone health: interpreting observational studies. J Intern Med 2017; 282:272-3.
  • 18. Tonnesen R, Hovind PH, Jensen LT, Schwarz P. Determinants of vitamin D status in young adults: influence of lifestyle, sociodemographic and anthropometric factors. BMC Public Health 2016; 16:385.
  • 19. Hightower JM, Dalessandri KM, Pope K, Hernandez GT. Low 25-Hydroxyvitamin D and Myofascial Pain: Association of Cancer, Colon Polyps, and Tendon Rupture. J Am Coll Nutr 2017; 36:455-61.
  • 20. Batista ED, Andretta A, de Miranda RC, Nehring J, Dos Santos Paiva E, Schieferdecker ME. Food intake assessment and quality of life in women with fibromyalgia. Rev Bras Reumatol Engl Ed. 2016 Mar-Apr;56(2):105-10.
  • 21. de Carvalho JF, Silva DN. Serum levels of vitamin B12 (cobalamin) in fibromyalgia. Rheumatol Int. 2016 May;36(5):741-2.
  • 22. Schiffman E, Ohrbach R, Truelove E, Look J, Anderson G, Goulet JP et al. International RDC/TMD Consortium Network, International association for Dental Research; Orofacial Pain Special Interest Group, International Association for the Study of Pain. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache. 2014 Winter;28(1):6-27.
  • 23. Ayouni I, Chebbi R, Hela Z, Dhidah M. Comorbidity between fibromyalgia and temporomandibular disorders: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jul;128(1):33-42.
  • 24. Gui MS, Pedroni CR, Aquino LM, Pimentel MJ, Alves MC, Rossini S et al. Facial pain associated with fibromyalgia can be marked by abnormal neuromuscular control: a cross-sectional study. Phys Ther. 2013 Aug;93(8):1092-101.
  • 25. Fujarra FJ, Kaziyama HH, Siqueira SR, Yeng LT, Camparis CM, Teixeira MJ et al. Temporomandibular disorders in fibromyalgia patients: are there different pain onset? Arq Neuropsiquiatr. 2016 Mar;74(3):195-200.
  • 26. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Jul;96(7):1911-30.
  • 27. Makrani AH, Afshari M, Ghajar M, Forooghi Z, Moosazadeh M. Vitamin D and fibromyalgia: a meta-analysis. Korean J Pain. 2017 Oct;30(4):250-257.
  • 28. McBeth J, Pye SR, O’Neill TW, Macfarlane GJ, Tajar A, Bartfai G, et al. Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study. Ann Rheum Dis 2010; 69:1448-52.
  • 29. Olama SM, Senna MK, Elarman MM, Elhawary G. Serum vitamin D level and bone mineral density in premenopausal Egyptian women with fibromyalgia. Rheumatol Int 2013; 33: 185-92.
  • 30. Karahan AY, Hüner B, Kuran B, Sezer N, Çelik C, Salbaş E et al. Vitamin D Düzeyi ile Non-spesifik Kas İskelet Sistemi Ağrıları Arasındaki İlişkinin Değerlendirilmesi: Çok Merkezli Retrospektif Bir Çalışma (İnme Çalışma Grubu). Turk J Osteoporos 2017; 23:61-66.
  • 31. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc 2003; 78:1463-70.
  • 32. Nickel JC, Iwasaki LR, Gonzalez YM, Gallo LM, Yao H. Mechanobehavior and Ontogenesis of the Temporomandibular Joint. J Dent Res. 2018 Oct;97(11):1185-1192.
  • 33. Yilmaz AD, Yazicioglu D, Tüzüner Öncül AM, Yilmaz E, Ereş G. Vitamin D receptor gene polymorphisms (Apa1 and Taq1) in temporomandibular joint internal derangement/osteoarthritis in a group of Turkish patients. Mol Biol Rep. 2018 Dec;45(6):1839-1848.
  • 34. Demir CY, Ersoz ME. Biochemical changes associated with temporomandibular disorders. J Int Med Res. 2019 Feb;47(2):765-771.
  • 35. Moreno-Fernández AM, Jiménez-Castellanos E, Iglesias-Linares A, Bueso-Madrid D, Fernández-Rodríguez A, de Miguel M. Fibromyalgia syndrome and temporomandibular disorders with muscular pain. A review. Mod Rheumatol. 2017 Mar;27(2):210-216.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Original Research Articles
Authors

Samed Şatır 0000-0002-5863-5928

Özlem Şatır 0000-0001-5428-8722

Publication Date March 25, 2022
Submission Date December 1, 2021
Published in Issue Year 2022Volume: 25 Issue: Supplement

Cite

EndNote Şatır S, Şatır Ö (March 1, 2022) TEMPOROMANDIBULAR JOINT DISEASE AND VITAMIN D LEVEL IN FIBROMYALGIA. Cumhuriyet Dental Journal 25 Supplement 29–33.
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