Antibiofilm Evaluation of Two Different Denture Liners Incorporated with Zirconium Oxide Nanoparticles

Gulfem Ergun; Ayşe Seda Ataol; Zeynep Şahin; Nurdan Saraç; Tuba Baygar; Aysel Uğur

doi:10.7126/cumudj.970931

EN

Antibiofilm Evaluation of Two Different Denture Liners Incorporated with Zirconium Oxide Nanoparticles

Abstract

Abstract Objectives: This in vitro study was purposed to examine the effects of incorporation nano-ZrO2 on antibiofilm activity, glucose sorption, weight change, and surface roughness of two different types of denture liners. Materials and Methods: Modified nano-ZrO2 were added to silicone-based and acrylic resin-based prosthetic lining materials at two different concentrations (0.5% and 1%). The antibiofilm potentials of test groups against Candida albicans (C. albicans), Staphylococcus aureus (S. aureus), and Streptococcus mutans (S. mutans) were determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) method. Surface roughness, weight change, and glucose sorption of denture liners were also evaluated after modifying with nano-ZrO2. Results: According to the antibiofilm activity results, 1% nano-ZrO2 addition to silicon-based and acrylic resin-based denture liners resulted in 16.48% and 13.39% of biofilm inhibition for S. aureus, respectively. 1% nano-ZrO2 addition to silicon-based denture liners also inhibited the S. mutans biofilm formation at an 8.16% rate. Nano-ZrO2 addition to the test groups had no inhibition effect on C. albicans biofilm formation. Surface roughness decreased significantly once nano-ZrO2 was added in tissue conditioner test groups (p=0.012), however, the addition of 0.5% nano-ZrO2 increased soft denture liner test group significantly (p<0.001). Conclusions: To overcome the microbial biofilm problems (especially against S. aureus and S. mutans) caused by the use of denture liners, addition of nano-ZrO2 might be a promising agent with its antibiofilm capacities.

Keywords

Supporting Institution

Mersin University

Project Number

2017-1-AP3-2181

Thanks

The authors would like to thank the Mersin University Scientific Research Projects Commission, which supported our study financially.

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Gulfem Ergun ^*
0000-0001-9981-5522
Türkiye

Ayşe Seda Ataol
0000-0003-3990-179X
Türkiye

Zeynep Şahin
0000-0003-2459-2912
Türkiye

Nurdan Saraç
0000-0001-7676-542X
Türkiye

Tuba Baygar
0000-0002-1238-3227
Türkiye

Aysel Uğur
0000-0002-5188-1106
Türkiye

Publication Date

March 25, 2022

Submission Date

July 13, 2021

Acceptance Date

December 29, 2021

Published in Issue

Year 2022 Volume: 25 Number: 1

DOI

https://doi.org/10.7126/cumudj.970931

IZ

https://izlik.org/JA35WS37SY

Cite

RIS / Bibtex

EndNote

Ergun G, Ataol AS, Şahin Z, Saraç N, Baygar T, Uğur A (March 1, 2022) Antibiofilm Evaluation of Two Different Denture Liners Incorporated with Zirconium Oxide Nanoparticles. Cumhuriyet Dental Journal 25 1 9–19.