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Year 2021, Volume: 24 Issue: 3, 286 - 298, 15.09.2021

Kavalipurapu Venkata Teja , Sindhu Ramesh , Sindhu Ramesh

https://doi.org/10.7126/cumudj.871091
Cited By: 2

Abstract

References

  • References: 1. Pak JG, White SN. Pain prevalence and severity before, during, and after root canal treatment: a systematic review. J Endod 2011;37:429–38.
  • 2. Genet JM, Wesselink PR, Thoden van Velzen SK. The incidence of preoperative and postoperative pain in endodontic therapy. Int Endod J1986;19:221–9.
  • 3. Hargreaves KM. Orofacial pain. Pain 2011;152:25-32.
  • 4. Gibbs J, Hargreaves K. Mechanisms of odontogenic and nonodontogenic pain. Ingles Endod 2008.
  • 5. Smith EA, Marshall JG, Selph SS, Barker DR, Sedgley CM. Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis. J Endod 2017;43:7–15.
  • 6. Bender IB. Pulpal pain diagnosis--a review. J Endod 2000;26:175–9.
  • 7. Levin L, Amit A, Ashkenazi M. Post-operative pain and use of analgesic agents following various dental procedures. Am J Dent 2006;19:245–7.
  • 8. Oliveira SM, Drewes CC, Silva CR, Trevisan G, Boschen SL, Moreira CG, et al. Involvement of mast cells in a mouse model of postoperative pain. Eur J Pharmacol 2011;672:88–95.
  • 9. Cooper SA, Quinn PD, MacAfee K, Hersh EV, Sullivan D, Lamp C. Ibuprofen controlled-release formulation. A clinical trial in dental impaction pain. Oral Surg Oral Med Oral Pathol 1993;75:677–83.
  • 10. Torabinejad M, Cymerman JJ, Frankson M, Lemon RR, Maggio JD, Schilder H. Effectiveness of various medications on postoperative pain following complete instrumentation. J Endod 1994;20:345–54.
  • 11. Attar S, Bowles WR, Baisden MK, Hodges JS, McClanahan SB. Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain. J Endod 2008;34:652–5.
  • 12. Whitten BH, Gardiner DL, Jeansonne BG, Lemon RR. current trends in endodontic treatment: report of a national survey. J Am Dent Assoc 1996;127:1333–41.
  • 13. Mehrvarzfar P, Abbott PV, Saghiri MA, Delvarani A, Asgar K, Lotfi M, et al. Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. Int Endod J 2012;45:76–82.
  • 14. Kissin I. Preemptive analgesia. Anesthesiology 2000;93:1138–43.
  • 15. Menhinick KA, Gutmann JL, Regan JD, Taylor SE, Buschang PH. The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study. Int Endod J 2004;37:531–41.
  • 16. Rogers MJ, Johnson BR, Remeikis NA, BeGole EA. Comparison of effect of intracanal use of ketorolac tromethamine and dexamethasone with oral ibuprofen on post treatment endodontic pain. J Endod 1999;25:381–4.
  • 17. Modaresi J, Dianat O, Mozayeni MA. The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;102:399–403.
  • 18. Mehlisch DR, Aspley S, Daniels SE, Bandy DP. Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-controlled, parallel-group, single-dose, two-center, modified factorial study. Clin Ther 2010;32:882–95.
  • 19. Wells LK, Drum M, Nusstein J, Reader A, Beck M. Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis. J Endod 2011;37:1608–12.
  • 20. Elzaki WM, Abubakr NH, Ziada HM, Ibrahim YE. Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. J Endod 2016;42:835–42.
  • 21. Metri M, Hegde S, Bhandi S. Effect of pretreatment diclofenac sodium on postendodontic pain: A randomised controlled trial. J Conserv Dent 2016;19:7.
  • 22. Jenarthanan S, Subbarao C. Comparative evaluation of the efficacy of diclofenac sodium administered using different delivery routes in the management of endodontic pain: A randomized controlled clinical trial. J Conserv Dent 2018;21:297.
  • 23. Taggar T, Wu D, Khan AA. A Randomized Clinical Trial Comparing 2 Ibuprofen Formulations in Patients with Acute Odontogenic Pain. J Endod 2017;43:674–8.
  • 24. Nabi S, Amin K, Masoodi A, Farooq R, Purra AR, Ahangar FA. Effect of preoperative ibuprofen in controlling postendodontic pain with and without low-level laser therapy in single visit endodontics: A randomized clinical study. Indian J Dent Res Off Publ Indian Soc Dent Res 2018;29:46–50.
  • 25. Joshi N, Mathew S, George JV, Hegde S, Bhandi S, Madhu KS. Comparative evaluation of the efficacy of two modes of delivery of Piroxicam (Dolonex(®)) for the management of postendodontic pain: A randomized control trial. J Conserv Dent 2016;19:301–5.
  • 26. Ramazani M, Hamidi MR, Moghaddamnia AA, Ramazani N, Zarenejad N. The Prophylactic Effects of Zintoma and Ibuprofen on Post-endodontic Pain of Molars with Irreversible Pulpitis: A Randomized Clinical Trial. Iran Endod J 2013;8:129–34.
  • 27. Praveen R, Thakur S, Kirthiga M. Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial. J Endod 2017;43:667–73.
  • 28. Sethi P, Agarwal M, Chourasia HR, Singh MP. Effect of single dose pretreatment analgesia with three different analgesics on postoperative endodontic pain: A randomized clinical trial. J Conserv Dent 2014;17:517–21.
  • 29. Bali R, Jyoti B, Paranjape T, Pathak S, Tiwari S, Bedi NS. Comparison of Pretreatment by Different Analgesics on Post-operative Endodontic Pain: A Clinical Study. Journal of International Oral Health 2016;8:109.
  • 30. Ashraf H, Naghlachi T, Ketabi MA. Comparison of the efficacy of prophylactic celecoxib, a Cox-2 inhibitor made in Iran, and placebo for post-endodontic pain reduction: a clinical double-blind study. Shahid Beheshti University Dent J 2013;31:155-61.
  • 31. Dejkam SM, Mirzayeerad S, Moghadamnia A, Gholinia H. Evaluation of pretreatment with gelofen and novafen on pain relief after endodontic treatment; A double-blind randomized clinical trial study. Caspian J Dent Res 2015;4:37-42.
  • 32. Arslan H, Topcuoglu HS, Aladag H. Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial. J Oral Sci 2011;53:157–61.
  • 33. Mokhtari F, Yazdi K, Mahabadi AM, Modaresi SJ, Hamzeheil Z. Effect of Premedication with Indomethacin and Ibuprofen on Postoperative Endodontic Pain: A Clinical Trial. Iran Endod J 2016;11:57–62.
  • 34. Berkman ND, Lohr KN, Ansari MT, Balk EM, Kane R, McDonagh M, et al. Grading the strength of a body of evidence when assessing health care interventions: an EPC update. J Clin Epidemiol 2015;68:1312–24.
  • 35. Nasri-Heir C, Khan J, Benoliel R, Feng C, Yarnitsky D, Kuo F, et al. Altered pain modulation in patients with persistent postendodontic pain. Pain 2015;156:2032–41.
  • 36. Nixdorf DR, Law AS, Lindquist K, Reams GJ, Cole E, Kanter K, et al. Frequency, impact, and predictors of persistent pain after root canal treatment: a national dental PBRN study. Pain 2016;157:159–65.

ANALGESIC EFFECT OF PRE-EMPTIVE ORAL NSAIDS ON POST-ENDODONTIC PAIN LEVELS IN SINGLE VISIT ENDODONTICS -A SYSTEMATIC REVIEW

Year 2021, Volume: 24 Issue: 3, 286 - 298, 15.09.2021

Kavalipurapu Venkata Teja , Sindhu Ramesh , Sindhu Ramesh

https://doi.org/10.7126/cumudj.871091
Cited By: 2

Abstract

Background: Pre-emptive analgesia is an anti-nociceptive treatment which reduces the postoperative pain by preventing the processing of altered afferent input. As most of the patients present with pain preoperatively have higher levels of released local inflammatory mediators. Thus, pretreatment analgesia decreases the establishment of central sensitization, a mechanism by which spinal neurons increase their response to peripheral nociceptive impulse. Objective: This systematic review aims to compare and evaluate the postoperative pain levels and analgesic intake on preoperative oral administration of NSAIDs in single visit root canal treatment. Data Sources: The present review was done according to PRISMA guidelines and was registered in the PROSPERO (Centre for Reviews and Dissemination University of York; http://www.crd.york.ac.uk/PROSPERO). Registration number - CRD42020195775. The research question was formulated based on the PICO strategy. A comprehensive electronic literature search was conducted across PubMed/Medline, Scopus and Cochrane Database independently by two reviewers. Study Eligibility Criteria: Articles published from January 1990 to May 2019 that focused on preemptive strategies in single visit root canal treatment were included in the present review. Based on specified inclusion and exclusion criteria’s, the selected articles were subjected to quality assessment, and the risk of bias was evaluated. Methods: A total of 6 articles were included, out of which three were hand searched. The overall risk of bias of included studies was moderate, and the study limitations were high.
Results: Among the studies included, Ibuprofen was considered as the best drug of choice in single visit endodontics.
Limitations: The present review was assessing only the effectiveness of NSAIDs in single visit root canal treatment. But ideally comprehensive literature should search on effectiveness in both single and multiple visit root canal treatments. Conclusion: The present systematic review concluded that ibuprofen was considered to be an effective drug in single visit root canal treatment.

Keywords

endodontics root canal pain

References

  • References: 1. Pak JG, White SN. Pain prevalence and severity before, during, and after root canal treatment: a systematic review. J Endod 2011;37:429–38.
  • 2. Genet JM, Wesselink PR, Thoden van Velzen SK. The incidence of preoperative and postoperative pain in endodontic therapy. Int Endod J1986;19:221–9.
  • 3. Hargreaves KM. Orofacial pain. Pain 2011;152:25-32.
  • 4. Gibbs J, Hargreaves K. Mechanisms of odontogenic and nonodontogenic pain. Ingles Endod 2008.
  • 5. Smith EA, Marshall JG, Selph SS, Barker DR, Sedgley CM. Nonsteroidal Anti-inflammatory Drugs for Managing Postoperative Endodontic Pain in Patients Who Present with Preoperative Pain: A Systematic Review and Meta-analysis. J Endod 2017;43:7–15.
  • 6. Bender IB. Pulpal pain diagnosis--a review. J Endod 2000;26:175–9.
  • 7. Levin L, Amit A, Ashkenazi M. Post-operative pain and use of analgesic agents following various dental procedures. Am J Dent 2006;19:245–7.
  • 8. Oliveira SM, Drewes CC, Silva CR, Trevisan G, Boschen SL, Moreira CG, et al. Involvement of mast cells in a mouse model of postoperative pain. Eur J Pharmacol 2011;672:88–95.
  • 9. Cooper SA, Quinn PD, MacAfee K, Hersh EV, Sullivan D, Lamp C. Ibuprofen controlled-release formulation. A clinical trial in dental impaction pain. Oral Surg Oral Med Oral Pathol 1993;75:677–83.
  • 10. Torabinejad M, Cymerman JJ, Frankson M, Lemon RR, Maggio JD, Schilder H. Effectiveness of various medications on postoperative pain following complete instrumentation. J Endod 1994;20:345–54.
  • 11. Attar S, Bowles WR, Baisden MK, Hodges JS, McClanahan SB. Evaluation of pretreatment analgesia and endodontic treatment for postoperative endodontic pain. J Endod 2008;34:652–5.
  • 12. Whitten BH, Gardiner DL, Jeansonne BG, Lemon RR. current trends in endodontic treatment: report of a national survey. J Am Dent Assoc 1996;127:1333–41.
  • 13. Mehrvarzfar P, Abbott PV, Saghiri MA, Delvarani A, Asgar K, Lotfi M, et al. Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. Int Endod J 2012;45:76–82.
  • 14. Kissin I. Preemptive analgesia. Anesthesiology 2000;93:1138–43.
  • 15. Menhinick KA, Gutmann JL, Regan JD, Taylor SE, Buschang PH. The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study. Int Endod J 2004;37:531–41.
  • 16. Rogers MJ, Johnson BR, Remeikis NA, BeGole EA. Comparison of effect of intracanal use of ketorolac tromethamine and dexamethasone with oral ibuprofen on post treatment endodontic pain. J Endod 1999;25:381–4.
  • 17. Modaresi J, Dianat O, Mozayeni MA. The efficacy comparison of ibuprofen, acetaminophen-codeine, and placebo premedication therapy on the depth of anesthesia during treatment of inflamed teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;102:399–403.
  • 18. Mehlisch DR, Aspley S, Daniels SE, Bandy DP. Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-controlled, parallel-group, single-dose, two-center, modified factorial study. Clin Ther 2010;32:882–95.
  • 19. Wells LK, Drum M, Nusstein J, Reader A, Beck M. Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis. J Endod 2011;37:1608–12.
  • 20. Elzaki WM, Abubakr NH, Ziada HM, Ibrahim YE. Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. J Endod 2016;42:835–42.
  • 21. Metri M, Hegde S, Bhandi S. Effect of pretreatment diclofenac sodium on postendodontic pain: A randomised controlled trial. J Conserv Dent 2016;19:7.
  • 22. Jenarthanan S, Subbarao C. Comparative evaluation of the efficacy of diclofenac sodium administered using different delivery routes in the management of endodontic pain: A randomized controlled clinical trial. J Conserv Dent 2018;21:297.
  • 23. Taggar T, Wu D, Khan AA. A Randomized Clinical Trial Comparing 2 Ibuprofen Formulations in Patients with Acute Odontogenic Pain. J Endod 2017;43:674–8.
  • 24. Nabi S, Amin K, Masoodi A, Farooq R, Purra AR, Ahangar FA. Effect of preoperative ibuprofen in controlling postendodontic pain with and without low-level laser therapy in single visit endodontics: A randomized clinical study. Indian J Dent Res Off Publ Indian Soc Dent Res 2018;29:46–50.
  • 25. Joshi N, Mathew S, George JV, Hegde S, Bhandi S, Madhu KS. Comparative evaluation of the efficacy of two modes of delivery of Piroxicam (Dolonex(®)) for the management of postendodontic pain: A randomized control trial. J Conserv Dent 2016;19:301–5.
  • 26. Ramazani M, Hamidi MR, Moghaddamnia AA, Ramazani N, Zarenejad N. The Prophylactic Effects of Zintoma and Ibuprofen on Post-endodontic Pain of Molars with Irreversible Pulpitis: A Randomized Clinical Trial. Iran Endod J 2013;8:129–34.
  • 27. Praveen R, Thakur S, Kirthiga M. Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial. J Endod 2017;43:667–73.
  • 28. Sethi P, Agarwal M, Chourasia HR, Singh MP. Effect of single dose pretreatment analgesia with three different analgesics on postoperative endodontic pain: A randomized clinical trial. J Conserv Dent 2014;17:517–21.
  • 29. Bali R, Jyoti B, Paranjape T, Pathak S, Tiwari S, Bedi NS. Comparison of Pretreatment by Different Analgesics on Post-operative Endodontic Pain: A Clinical Study. Journal of International Oral Health 2016;8:109.
  • 30. Ashraf H, Naghlachi T, Ketabi MA. Comparison of the efficacy of prophylactic celecoxib, a Cox-2 inhibitor made in Iran, and placebo for post-endodontic pain reduction: a clinical double-blind study. Shahid Beheshti University Dent J 2013;31:155-61.
  • 31. Dejkam SM, Mirzayeerad S, Moghadamnia A, Gholinia H. Evaluation of pretreatment with gelofen and novafen on pain relief after endodontic treatment; A double-blind randomized clinical trial study. Caspian J Dent Res 2015;4:37-42.
  • 32. Arslan H, Topcuoglu HS, Aladag H. Effectiveness of tenoxicam and ibuprofen for pain prevention following endodontic therapy in comparison to placebo: a randomized double-blind clinical trial. J Oral Sci 2011;53:157–61.
  • 33. Mokhtari F, Yazdi K, Mahabadi AM, Modaresi SJ, Hamzeheil Z. Effect of Premedication with Indomethacin and Ibuprofen on Postoperative Endodontic Pain: A Clinical Trial. Iran Endod J 2016;11:57–62.
  • 34. Berkman ND, Lohr KN, Ansari MT, Balk EM, Kane R, McDonagh M, et al. Grading the strength of a body of evidence when assessing health care interventions: an EPC update. J Clin Epidemiol 2015;68:1312–24.
  • 35. Nasri-Heir C, Khan J, Benoliel R, Feng C, Yarnitsky D, Kuo F, et al. Altered pain modulation in patients with persistent postendodontic pain. Pain 2015;156:2032–41.
  • 36. Nixdorf DR, Law AS, Lindquist K, Reams GJ, Cole E, Kanter K, et al. Frequency, impact, and predictors of persistent pain after root canal treatment: a national dental PBRN study. Pain 2016;157:159–65.
There are 36 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Review
Authors

Kavalipurapu Venkata Teja 0000-0003-0123-8873

Sindhu Ramesh 0000-0003-2617-6592

Sindhu Ramesh 0000-0003-0088-0098

Publication Date September 15, 2021
Submission Date January 30, 2021
Published in Issue Year 2021Volume: 24 Issue: 3

Cite

EndNote Venkata Teja K, Ramesh S, Ramesh S (September 1, 2021) ANALGESIC EFFECT OF PRE-EMPTIVE ORAL NSAIDS ON POST-ENDODONTIC PAIN LEVELS IN SINGLE VISIT ENDODONTICS -A SYSTEMATIC REVIEW. Cumhuriyet Dental Journal 24 3 286–298.

Cited By

Efficacy of preoperative and postoperative medications in reducing pain after non-surgical root canal treatment: an umbrella review
Clinical Oral Investigations
https://doi.org/10.1007/s00784-024-05876-z
Clinical correlation of salivary alpha-amylase levels with pain intensity in patients undergoing emergency endodontic treatment
BMC Oral Health
https://doi.org/10.1186/s12903-023-03195-5
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