Objective: The aim of this study was to determinate of the
effective time of different denture cleanser tablets on the removal of Candida albicans on various base resins.
Materials
and Methods: Conventional
heat cured resin, high impact resin, autopolymerized resin, and polyamide
resin were used. 160 samples were prepared for each resin type. The biofilm of C. albicans was formed on the resins and then exposed to alkaline
peroxide tablet and enzymatic tablets for 3-5-10-20-40-80-160-200 minutes. Cell
viability was assessed by MTT test. 3-way ANOVA was used for statistical
analysis.
Results: The
effect of resin type, tablet type and application time on cell viability of C. albicans were found to be significant
(p<0.05). Cell death was at least
65% on the resins even at the minimum time. Furthermore, as the duration of
administration of both tablets increased, cell viability in all resins tended
to decrease. The administration of both tablets on all resins for 10 min
resulted in approximately 80% cell death. Additionally, the most significant
antimicrobial activities of the tablets were determined on 20th
minutes. The alkaline peroxide tablet on all base resins for application
periods of 3 to 200 minutes was generally more effective than the enzymatic
tablet.
Conclusion:
Alkaline peroxide and enzymatic cleanser tablets showed remarkable anticandidal
activity for all resins. The patients with risk of C. albicans infection should keep their prostheses in cleanser
tablets for at least 20 minutes. Furthermore, the anticandidal effect tended to
increase with prolonged exposure time.
Amaç:
Bu çalışmanın amacı, çeşitli protez kaide rezinleri üzerindeki Candida albicans'ın uzaklaştırılmasında farklı
protez temizleyici tabletlerin etkin sürelerinin belirlenmesidir.
Gereç ve Yöntemler: Çalışmada geleneksel ısıyla polimerize olan rezin, yüksek çarpma
dayanıklı rezin, otopolimerize rezin ve poliamid rezin kullanıldı. Her rezin
tipi için 160 numune hazırlandı. C.
albicans'ın biyofilmi rezinler üzerinde oluşturuldu ve daha sonra
3-5-10-20-40-80-160-200 dakika boyunca alkalin peroksit tablet ve enzimatik
tablete maruz bırakıldı. Hücre canlılığı MTT testi ile değerlendirildi.
İstatistiksel analiz için 3 yönlü ANOVA kullanıldı.
Bulgular:
Rezin tipi, tablet tipi ve uygulama süresinin rezinler üzerindeki C. albicans'ın hücre canlılığı üzerine
etkisi anlamlı bulundu (p<0.05). Minimum
sürede bile rezinlerde en az % 65 hücre ölümü meydana geldi. Bununla birlikte,
her iki tabletin uygulama süresi arttıkça, tüm rezinlerdeki hücre canlılığı azalma
eğilimi gösterdi. Rezinlerin her iki tablete de 10 dakika maruz bırakılması tüm
rezinlerde yaklaşık % 80 hücre ölümüne neden oldu. Bununla birlikte,
tabletlerin en önemli antimikrobiyal aktiviteleri 20. dakika da görülmüştür. Alkalin
peroksit tablet, tüm protez kaide rezinleri üzerinde 3 ila 200 dakikalık uygulama
süreleri için genel olarak enzimatik tabletten daha etkili olmuştur.
Sonuç:
Alkalin peroksit ve enzimatik temizleyici tabletler, tüm rezinler için kayda
değer bir antikandidal aktivite göstermiştir. C. albicans enfeksiyonu riski taşıyan hastalar protezlerini temizleyici
tabletlerde en az 20 dakika tutmalıdır. Bununla birlikte, antikandidal etki tablet
süresinin uzaması ile artma eğilimindedir.
Primary Language | English |
---|---|
Subjects | Health Care Administration |
Journal Section | Original Research Articles |
Authors | |
Publication Date | September 9, 2019 |
Submission Date | May 16, 2019 |
Published in Issue | Year 2019Volume: 22 Issue: 3 |
Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.
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