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Year 2015, Volume: 18 Issue: 3, 300 - 310, 12.08.2015

Zuhal Kırzıoğlu Tuğba Tasa

Abstract

The survival rate of childhood cancer, for 5 years, reached 80% after the progresion of cancer treatment in the last 20 years. Therefore cancer is a chronic disease that characterised by acute attacks. Systemic and oral complications increase with the increasing of life span. Infection risk, hospitalization period and treatment cost incerase with develping of oral complications during the treatment and after the treatment like pain, nutritional problems, disfagi, anorexia. And these factors effect treatment prognosis negatively. One to third of sepsis in all of these patients depends on oral infections. So, pediatric dentistry has an important role on cancer multydiciplinary treatment protocols. Dental approaches should be completed effectively in a short time according to medical history and treatment protocol. Although protective applications like oral hygiene education, diet regulation, flour application, prevention of trismus, lip care are same in all periods of cancer patients, additional applications are necessary in teratment steps. In our study we will check dental applications upto periods according to literatures

Keywords

Childhood cancer;Dental application

References

  • Belfield PM, Dwyer AA. Oral complications of childhood cancer and its treatment: current best practice. Eur J Cancer 2004;40(7): 1035-41.
  • Pizzo PA, Poplack DG. Principles and practice of pediatric oncology. 4th. ed. Lippincott Williams & Wilkins, 2001; 1051-89
  • -
  • Carrillo C, Vizeu H, Soares-Júnior LA, Fava M, Filho VO. Dental approach in the pediatric oncology patient: characteristics of the population treated at the dentistry unit in a pediatric oncology brazilian teaching hospital. Clinics 2010;65(6):569-73.
  • Kebudi R, Turkish Pediatric Oncology Group. Pediatric oncology in Turkey. J Pediatr Hematol Oncol 2012;34 (Suppl 1):12–14.
  • Selwood K. Ward E. Gibson F. Assessment and management of nutritional challenges in children’s cancer care: A survey of current practice in the United Kingdom, European Journal of Oncology Nursing, 2010;14(5):439-46.
  • Hogan R. Implementation of an oral care protocol and its effects on oral mucositis. J Pediatr Oncol Nurs 2009;26(3):125-35.
  • Otmani N. Oral and maxillofacial side effects of radiation therapy on children. J Can Dent Assoc 2007;73(3):257-61.
  • -
  • National Cancer Institute: PDQ® Oral complications of chemotherapy and head/neck radiation. Bethesda, MD: National Cancer Institute. February 28, 2013. Available at: “http://cancer.gov/cancertopics/pdq/supportivecare/oralcomplications/HealthProfessional.” 2013.
  • -
  • American Academy of Pediatric Dentistry. Guideline on dental management of pediatric patients receiving chemotherapy, hematopoietic cell transplantation, and/or radiation. Pediatr Dent. 2013 Sep-Oct;35(5):185-93.
  • Peterson DE, Bensadoun RJ, Roila F, ESMO Guidelines Working Group. Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines. Ann Oncol 2011;22(Suppl 6):78-84.
  • Lalla RV, Brennan MT, Schubert MM. Oral complications of cancer therapy. In: Yagiela JA, Dowd FJ, Johnson BS, Marrioti AJ, Neidle EA, eds. Pharmacology and Therapeutics for Dentistry. 6th ed. St. Louis, Mo: Mosby-Elsevier; 2011:782-98.
  • -
  • Schubert MM, Peterson DE. Oral complications of hematopoietic cell transplantation. In: Appelbaum RF, Forman SJ, Negrin RS, Blume KG, eds. Thomas’ Hematopoietic Cell Transplantation: Stem Cell Transplantation, 4th ed. Oxford, UK: Wiley-Blackwell; 2009:1589-607.
  • Bavier AR. Nursing management of acute oral complications of cancer. 1990;(9):123-8.
  • -
  • Kozai K, Iwai T, Miura K. Residual contamination of toothbrushes by microorganisms. ASDC J Dent Child. 1989;56(3):201-4.
  • Saravia ME, Nelson-Filho P, Silva RAB, Faria G, Rossi MA, Ito IY. Viability of streptococcus mutans toothbrush bristles. J Dent Child 2008;75(1):29–32.
  • Glass RT. The infected toothbrush, the infected denture, and transmission of disease. Compend Contin Educ Dent 1992;13(7):592-8.
  • da Silva LAB, Nelson‐Filho P, Saravia ME, de Rossi A, Lucısano MP, da Silva RAB. Mutans streptococci remained viable on toothbrush bristles, in vivo, for 44 h. Int J Paediatr Dent. 2013 Nov 21.
  • -
  • Komiyama EY, Back-Brito GN, Balducci I, Koga-Ito CY. Evaluation of alternative methods for the disinfection of toothbrushes. Braz Oral Res. 2010;24(1):28-33.
  • Spolidorio DM, Tardivo TA, dos Reis Derceli J, Neppelenbroek KH, Duque C, Spolidorio LC, Pires JR. Evaluation of two alternative methods for disinfection of toothbrushes and tongue scrapers. Int J Dent Hyg. 2011;9(4):279-83.
  • Ankola AV, Hebbal M, Eshwar S. How clean is the toothbrush that cleans your tooth? Int J Dent Hyg. 2009 Nov;7(4):237-40.
  • Little JW, Falace DA, Miller CS, Rhodus NL. Cancer and oral care of the cancer patient. In: Little and Falace’s Dental Management of the Medically Compromised Patient, 8th ed. St. Louis, Mo: Elsevier-Mosby; 2012: 459-92.
  • Sonis ST. Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol 1998;34(1):39-43.
  • Peters E, Monopoli M, Woo SB, Sonis S. Assessment of the need for treatment of postendodontic asymptomatic periapical radiolucencies in bone marrow transplant recipients. Oral Surg Oral Med Oral Pathol 1993;76(1):45-8.
  • Sheller B, Williams B. Orthodontic management of patients with hematologic malignancies. Am J Orthod Dentofacial Orthop. 1996;109(6):575-80.
  • American Association of Oral and Maxillofacial Surgeons. White paper: Evidence based third molar surgery 2011. Available at: “http://www.aaoms.org/docs/evidence_based_third_molar_surgery.pdf” 2013.
  • Hong CH, da Fonseca MA. Considerations in the pediatric population with cancer. Dent Clin N Am 2008;52(1): 155-81
  • da Fonseca MA. Dental care of the pediatric cancer patient. Pediatr Dent. 2004; 26(1):53-7.
  • Majorana A, Schubert MM, Porta F, Ugazio AG, Sapelli PL. Oral complications of pediatric hematopoietic cell transplantation: diagnosis and management. Support Care Cancer. 2000;8(5):353–65.
  • Baade PD, Youlden DR, Valery PC, Hassall T, Ward L, Green AC, Aitken JF. Trends in incidence of childhood cancer in Australia, 1983–2006. Br J Cancer 2010(3);102:620–6.
  • Lopes NN, Plapler H, Chavantes MC, Lalla RV, Yoshimura EM, Alves MT. Cyclooxygenase-2 and vascular endothelial growth factor expression in 5-fluorouracil-induced oral mucositis in hamsters: evaluation of two low-intensity laser protocols. Support Care Cancer. 2009;17(11):1409-15.
  • Wong SF, Wilder-Smith P. Pilot study of laser effects on oral mucositis in patients receiving chemotherapy. The Cancer Journal. 2002;8(3):247-54.
  • Pession A, Locatelli F, Zecca M, Rondelli R, Prete A, Bonetti F, Paolucci G. Cyclosporine-A as GVHD prophylaxis in allogeneic BMT for childhood acute leukemia. Bone Marrow Transplant 1998;21 [Suppl 2] :50-2.
  • Greenberg MS. Prechemotherapy dental treatment to prevent bacteremia. NCI Monogr. 1990;(9):49-50.
  • Vilavlanca JG, Steiner M, Kersey J, Ramsay NK, Ferrieri P, Haake R, Weisdorf D. The clinical spectrum of infections with viridans streptococci in bone marrow transplant patients. Bone Marrow Transplant 1990;5(6):387-93.
  • Connolly SF, Lockhart PB, Sonis ST. Severe oral hemorrhage and sepsis following bone marrow transplant failure. Oral Surg Oral Med Oral Pathol 1983;56(5):483–88.
  • Barker GJ Current practices in the oral management of the patient undergoing chemotherapy or bone marrow transplantation. Support Care Cancer 1999;7(1):17–20.
  • Scully C, Epstein JB. Oral health care for the cancer patient. Eur J Cancer B Oral Oncol 1996;32(5):281-92.
  • Watters AL, Epstein JB, Agulnik M. Oral complications of targeted cancer therapies: a narrative literature review. Oral Oncol. 2011;47(6):441-8.
  • Schubert MM, Sullivan KM. Recognition, incidence, and management of oral graft-versus-host disease. NCI Monogr. 1990;(9):135-43.
  • Elad S, Thierer T, Bitan M, Shapira MY, Meyerowitz C. A decision analysis: The dental management of patients prior to hematology cytotoxic therapy or hematopoietic stem cell transplantation. Oral Oncol 2008;44(1):37-42.
  • Kaste SC, Goodman P, Leisenring W, Stovall M, Hayashi RJ, Yeaze M. Impact of radiation and chemotherapy on risk of dental abnormalities. Cancer 2009; 115(24):5817-27.
  • Municucci EM, Lopes LF, Crocci AJ. Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia. Leuk Res 2003;27(1):45-50.
  • Cohen A, Rovelli R, Zecca S, Van-Lint MT, Parodi L, Grasso L, Uderzo C. Endocrine late effects in children who underwent bone marrow transplantation: review. Bone Marrow Transplant 1998;21 [Suppl 2]:64–7.
  • Saad F, Brown JE, Van Poznak C, Ibrahim T, Stemmer SM, Stopeck AT, Diel IJ, Takahashi S, Shore N, Henry DH, Barrios CH, Facon T, Senecal F, Fizazi K, Zhou L, Daniels A, Carrière P, Dansey R. Incidence, risk factors, and outcomes of osteonecrosis of the jaw: Integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. Ann Oncol 2012;23(5):1341-7.
  • Kuhl S, Walter C, Acham S, Pfeffer R, Lambrecht JT. Bisphosphonate related osteonecrosis of the jaws- A review. Oral Oncology 2012;48(10):938-47.
  • Dodson TB. Intravenous bisphosphonate therapy and bisphosphonate related osteonecrosis of the jaws. J Oral Maxillofac Surg 2009;67(suppl 1):44-52.
  • Dahllöf G, Jönsson A, Ulmner M, Huggare J. Orthodontic treatment in long-term survivors after bone marrow transplantation. Am J Orthod Dentofacial Orthop 2001; 120(5):459-65.
  • Zahrowski JJ. Bisphosphonate treatment: An orthodontic concern for a proactive approach. Am J Orthod Dentofacial Orthop 2007;131(3):311-20.

KANSER TANISI ALAN ÇOCUK HASTALARDA ORAL SAĞLIĞIN SAĞLANMASI

Year 2015, Volume: 18 Issue: 3, 300 - 310, 12.08.2015

Zuhal Kırzıoğlu Tuğba Tasa

Abstract

Running Title:Kanser Hastalarında Oral Sağlık

Kanser tedavisinde, son 20 yıl içinde gerçekleşen ilerlemeler sayesinde, çocukluk kanserlerinde 5 yıllık sağ kalım oranı, %80’lere ulaşmıştır. Bu nedenle kanser, akut ataklarla seyreden, uzun süreli kronik bir hastalık olarak görülmektedir. Yaşam süresinin artması ile sistemik komplikasyonlarla birlikte oral komplikasyonlar da artmaktadır. Tedavi sırasında ve sonrasında gelişen oral komplikasyonlar, ağrı, konuşma ve yutkunma güçlüğü, beslenme bozukluğu gibi ciddi sorunlara yol açarak; hastanın yaşam kalitesini, enfeksiyon riskini, hastanede kalış süresini, tedavi maliyetini arttırmakta, prognozunu olumsuz etkilemektedir. Bu hastalarda gelişen tüm septisemilerin, üçte birinin oral enfeksiyonlara bağlı olduğu bilinmektedir. Bu nedenle, multidisipliner bir yaklaşım gerektiren bu tedavide çocuk diş hekiminin rolü oldukça önemlidir. Dental müdahaleler, hastanın tıbbi geçmişi, tedavi protokolü ve sağlık durumuna dikkat edilerek hızlı ve etkili bir şekilde yapılmalıdır. Kanser hastalarının her döneminde, oral hijyen eğitimi, diyet düzenlemesi, flor uygulaması, trismusun önlenmesi, dudak bakımı gibi koruyucu uygulamalar aynı olsa da, tedavi basamaklarında ilave uygulamalar gerekmektedir. Bu derlemede, literatürler ışığında dönemlere göre dental uygulamalar gözden geçirilecektir.

Keywords

Çocukluk çağı kanserleri; dental uygulama

References

  • Belfield PM, Dwyer AA. Oral complications of childhood cancer and its treatment: current best practice. Eur J Cancer 2004;40(7): 1035-41.
  • Pizzo PA, Poplack DG. Principles and practice of pediatric oncology. 4th. ed. Lippincott Williams & Wilkins, 2001; 1051-89
  • -
  • Carrillo C, Vizeu H, Soares-Júnior LA, Fava M, Filho VO. Dental approach in the pediatric oncology patient: characteristics of the population treated at the dentistry unit in a pediatric oncology brazilian teaching hospital. Clinics 2010;65(6):569-73.
  • Kebudi R, Turkish Pediatric Oncology Group. Pediatric oncology in Turkey. J Pediatr Hematol Oncol 2012;34 (Suppl 1):12–14.
  • Selwood K. Ward E. Gibson F. Assessment and management of nutritional challenges in children’s cancer care: A survey of current practice in the United Kingdom, European Journal of Oncology Nursing, 2010;14(5):439-46.
  • Hogan R. Implementation of an oral care protocol and its effects on oral mucositis. J Pediatr Oncol Nurs 2009;26(3):125-35.
  • Otmani N. Oral and maxillofacial side effects of radiation therapy on children. J Can Dent Assoc 2007;73(3):257-61.
  • -
  • National Cancer Institute: PDQ® Oral complications of chemotherapy and head/neck radiation. Bethesda, MD: National Cancer Institute. February 28, 2013. Available at: “http://cancer.gov/cancertopics/pdq/supportivecare/oralcomplications/HealthProfessional.” 2013.
  • -
  • American Academy of Pediatric Dentistry. Guideline on dental management of pediatric patients receiving chemotherapy, hematopoietic cell transplantation, and/or radiation. Pediatr Dent. 2013 Sep-Oct;35(5):185-93.
  • Peterson DE, Bensadoun RJ, Roila F, ESMO Guidelines Working Group. Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines. Ann Oncol 2011;22(Suppl 6):78-84.
  • Lalla RV, Brennan MT, Schubert MM. Oral complications of cancer therapy. In: Yagiela JA, Dowd FJ, Johnson BS, Marrioti AJ, Neidle EA, eds. Pharmacology and Therapeutics for Dentistry. 6th ed. St. Louis, Mo: Mosby-Elsevier; 2011:782-98.
  • -
  • Schubert MM, Peterson DE. Oral complications of hematopoietic cell transplantation. In: Appelbaum RF, Forman SJ, Negrin RS, Blume KG, eds. Thomas’ Hematopoietic Cell Transplantation: Stem Cell Transplantation, 4th ed. Oxford, UK: Wiley-Blackwell; 2009:1589-607.
  • Bavier AR. Nursing management of acute oral complications of cancer. 1990;(9):123-8.
  • -
  • Kozai K, Iwai T, Miura K. Residual contamination of toothbrushes by microorganisms. ASDC J Dent Child. 1989;56(3):201-4.
  • Saravia ME, Nelson-Filho P, Silva RAB, Faria G, Rossi MA, Ito IY. Viability of streptococcus mutans toothbrush bristles. J Dent Child 2008;75(1):29–32.
  • Glass RT. The infected toothbrush, the infected denture, and transmission of disease. Compend Contin Educ Dent 1992;13(7):592-8.
  • da Silva LAB, Nelson‐Filho P, Saravia ME, de Rossi A, Lucısano MP, da Silva RAB. Mutans streptococci remained viable on toothbrush bristles, in vivo, for 44 h. Int J Paediatr Dent. 2013 Nov 21.
  • -
  • Komiyama EY, Back-Brito GN, Balducci I, Koga-Ito CY. Evaluation of alternative methods for the disinfection of toothbrushes. Braz Oral Res. 2010;24(1):28-33.
  • Spolidorio DM, Tardivo TA, dos Reis Derceli J, Neppelenbroek KH, Duque C, Spolidorio LC, Pires JR. Evaluation of two alternative methods for disinfection of toothbrushes and tongue scrapers. Int J Dent Hyg. 2011;9(4):279-83.
  • Ankola AV, Hebbal M, Eshwar S. How clean is the toothbrush that cleans your tooth? Int J Dent Hyg. 2009 Nov;7(4):237-40.
  • Little JW, Falace DA, Miller CS, Rhodus NL. Cancer and oral care of the cancer patient. In: Little and Falace’s Dental Management of the Medically Compromised Patient, 8th ed. St. Louis, Mo: Elsevier-Mosby; 2012: 459-92.
  • Sonis ST. Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity. Oral Oncol 1998;34(1):39-43.
  • Peters E, Monopoli M, Woo SB, Sonis S. Assessment of the need for treatment of postendodontic asymptomatic periapical radiolucencies in bone marrow transplant recipients. Oral Surg Oral Med Oral Pathol 1993;76(1):45-8.
  • Sheller B, Williams B. Orthodontic management of patients with hematologic malignancies. Am J Orthod Dentofacial Orthop. 1996;109(6):575-80.
  • American Association of Oral and Maxillofacial Surgeons. White paper: Evidence based third molar surgery 2011. Available at: “http://www.aaoms.org/docs/evidence_based_third_molar_surgery.pdf” 2013.
  • Hong CH, da Fonseca MA. Considerations in the pediatric population with cancer. Dent Clin N Am 2008;52(1): 155-81
  • da Fonseca MA. Dental care of the pediatric cancer patient. Pediatr Dent. 2004; 26(1):53-7.
  • Majorana A, Schubert MM, Porta F, Ugazio AG, Sapelli PL. Oral complications of pediatric hematopoietic cell transplantation: diagnosis and management. Support Care Cancer. 2000;8(5):353–65.
  • Baade PD, Youlden DR, Valery PC, Hassall T, Ward L, Green AC, Aitken JF. Trends in incidence of childhood cancer in Australia, 1983–2006. Br J Cancer 2010(3);102:620–6.
  • Lopes NN, Plapler H, Chavantes MC, Lalla RV, Yoshimura EM, Alves MT. Cyclooxygenase-2 and vascular endothelial growth factor expression in 5-fluorouracil-induced oral mucositis in hamsters: evaluation of two low-intensity laser protocols. Support Care Cancer. 2009;17(11):1409-15.
  • Wong SF, Wilder-Smith P. Pilot study of laser effects on oral mucositis in patients receiving chemotherapy. The Cancer Journal. 2002;8(3):247-54.
  • Pession A, Locatelli F, Zecca M, Rondelli R, Prete A, Bonetti F, Paolucci G. Cyclosporine-A as GVHD prophylaxis in allogeneic BMT for childhood acute leukemia. Bone Marrow Transplant 1998;21 [Suppl 2] :50-2.
  • Greenberg MS. Prechemotherapy dental treatment to prevent bacteremia. NCI Monogr. 1990;(9):49-50.
  • Vilavlanca JG, Steiner M, Kersey J, Ramsay NK, Ferrieri P, Haake R, Weisdorf D. The clinical spectrum of infections with viridans streptococci in bone marrow transplant patients. Bone Marrow Transplant 1990;5(6):387-93.
  • Connolly SF, Lockhart PB, Sonis ST. Severe oral hemorrhage and sepsis following bone marrow transplant failure. Oral Surg Oral Med Oral Pathol 1983;56(5):483–88.
  • Barker GJ Current practices in the oral management of the patient undergoing chemotherapy or bone marrow transplantation. Support Care Cancer 1999;7(1):17–20.
  • Scully C, Epstein JB. Oral health care for the cancer patient. Eur J Cancer B Oral Oncol 1996;32(5):281-92.
  • Watters AL, Epstein JB, Agulnik M. Oral complications of targeted cancer therapies: a narrative literature review. Oral Oncol. 2011;47(6):441-8.
  • Schubert MM, Sullivan KM. Recognition, incidence, and management of oral graft-versus-host disease. NCI Monogr. 1990;(9):135-43.
  • Elad S, Thierer T, Bitan M, Shapira MY, Meyerowitz C. A decision analysis: The dental management of patients prior to hematology cytotoxic therapy or hematopoietic stem cell transplantation. Oral Oncol 2008;44(1):37-42.
  • Kaste SC, Goodman P, Leisenring W, Stovall M, Hayashi RJ, Yeaze M. Impact of radiation and chemotherapy on risk of dental abnormalities. Cancer 2009; 115(24):5817-27.
  • Municucci EM, Lopes LF, Crocci AJ. Dental abnormalities in children after chemotherapy treatment for acute lymphoid leukemia. Leuk Res 2003;27(1):45-50.
  • Cohen A, Rovelli R, Zecca S, Van-Lint MT, Parodi L, Grasso L, Uderzo C. Endocrine late effects in children who underwent bone marrow transplantation: review. Bone Marrow Transplant 1998;21 [Suppl 2]:64–7.
  • Saad F, Brown JE, Van Poznak C, Ibrahim T, Stemmer SM, Stopeck AT, Diel IJ, Takahashi S, Shore N, Henry DH, Barrios CH, Facon T, Senecal F, Fizazi K, Zhou L, Daniels A, Carrière P, Dansey R. Incidence, risk factors, and outcomes of osteonecrosis of the jaw: Integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. Ann Oncol 2012;23(5):1341-7.
  • Kuhl S, Walter C, Acham S, Pfeffer R, Lambrecht JT. Bisphosphonate related osteonecrosis of the jaws- A review. Oral Oncology 2012;48(10):938-47.
  • Dodson TB. Intravenous bisphosphonate therapy and bisphosphonate related osteonecrosis of the jaws. J Oral Maxillofac Surg 2009;67(suppl 1):44-52.
  • Dahllöf G, Jönsson A, Ulmner M, Huggare J. Orthodontic treatment in long-term survivors after bone marrow transplantation. Am J Orthod Dentofacial Orthop 2001; 120(5):459-65.
  • Zahrowski JJ. Bisphosphonate treatment: An orthodontic concern for a proactive approach. Am J Orthod Dentofacial Orthop 2007;131(3):311-20.
There are 54 citations in total.

Details

Primary Language Turkish
Journal Section Review
Authors

Zuhal Kırzıoğlu

Tuğba Tasa

Publication Date August 12, 2015
Submission Date April 30, 2014
Published in Issue Year 2015Volume: 18 Issue: 3

Cite

EndNote Kırzıoğlu Z, Tasa T (August 1, 2015) KANSER TANISI ALAN ÇOCUK HASTALARDA ORAL SAĞLIĞIN SAĞLANMASI. Cumhuriyet Dental Journal 18 3 300–310.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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