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Kavite dezenfeksiyonu amacı ile kullanılabilen ticari antibakteriyel jellerin mikro-gerilme bağlanma dayanımı üzerine etkinliklerinin değerlendirilmesi

Year 2012, Volume: 15 Issue: 4, 288 - 296, 17.04.2012

Tamer Tüzüner , Ayça Ulusoy , Ozgul Baygin , Görkem Yahyaoğlu İlkay Yalçın

https://doi.org/10.7126/cdj.2012.1510
Cited By: 2

Abstract

Objectives: Insufficient removal of caries-affected enamel and dentin represents a serious problem in restorative dentistry, as any bacteria remaining in the cavity after preparation may cause secondary caries. In order to provide an aseptic environment before pulp capping and lining, the use of an antibacterial material as a cavity disinfectant has been recommended. The aim of this study was to evaluate the role of commercially available gel formulations on  the micro-tensile bond strength (MTBS) of a total etch system.

Materials and Methods: Commercially available gel formulations with the contents of chlorhexidine (Corsodyl gel- %1CHX-COG), (Cervitec gel-%0.2 CHX+%0.2 sodium fluoride-CEG), aloe vera (Forever Bright-FOB) and hyaluronic acid (Gengigel-GEG) applicable as cavity disinfectants were used. No disinfectant was applied in the control group (CON). Ten human third molar free of caries were used in the study. Gels were applied for 1 minute just before bonding following total etch application in the gel groups, removed with sterile pellets and air-dried. Then composite restorations were applied. Ten composite-dentin rods (surface area of 1.0±0.1 mm2) were generated in each group from specimens stored in distilled water in 370C for 24 hours. These specimens then were subjected to MTBS test applying at a crosshead speed of 1 mm/min. Bond strength values between composite-dentin were recorded as megapascal and failure types were evaluated. Statistical differences were evaluated with one-way ANOVA and Tukey’s test at the signifince level of p<0.05.

Results: All the gels applied created lower MTBS levels compared with CON group (p<0.05). No difference was detected among the gels; CEG>COG>GEG>FOB (p>0.05). While mixed failure  type was dominant in the CON group, only adhesive failure  type was observed in all the other groups.

Conclusions: Besides the antibacterial properties of these gel formulations, alterations occured in micromechanical adhesion and clinical performances should not be overlooked.

Keywords: Cavity disinfectant, antibacterial gel, micro-tensile bond strength.

 

ÖZET

Amaç: Çürüğün yeterli temizlenmemesi sonucu kavite içerisinde geride kalan bakteri miktarı restoratif diş hekimliğinde sorun oluşturmaktadır. Pulpa kaplaması veya kaide materyali uygulanımı öncesi kavite dezenfeksiyonu önerilmektedir. Bu çalışmanın amacı ticari olarak piyasada yer alan jel formülasyonlarının total etch bir kompozit sistemin mikro-gerilme bağlanma dayanımı (MGBD) üzerinde oluşturduğu etkinin değerlendirilmesidir.

Gereç ve Yöntem: Ticari olarak piyasada yeralan klorheksidin [(Corsdoyl gel- %1KHX-COG), (Cervitec gel-%0,2 KHX+%0,2 sodyum fluorid-CEG), aleo vera (Forever Bright-FOB) ve hyaluronik asit (Gengigel-GEG) içerikli ticari antibakteriyel jel formülasyonları bu çalışmada kullanıldı. Kontrol grubunda ise (KON) herhangi bir dezenfektan uygulanmadı. Çalışmada her bir grup için 2 adet olmak üzere toplam 10 adet çekilmiş çürüksüz insan 3.molar dişi kullanıldı. Jel gruplarında total etch sistem uygulamanın ardından bonding materyalin kullanımından hemen önce 1 dakika süre ile jeller uygulandı, steril peletle ortamdan uzaklaştırıldı ve hava ile kurutuldu. Daha sonra kompozit restorasyonlar yapıldı. 24 saat süre ile 370C’de distile suda saklanan örneklerden her bir grupta 10’ar adet olacak şekilde (kesit çapı 1,0±0,1 mm2) kompozit-dentin çubuk örnekleri oluşturuldu. Bu örnekler daha sonra dakikada 1 mm kuvvet uygulanarak MGBD testine tabi tutuldu. Kompozit-dentin arası bağlanma dayanım değerleri megapaskal cinsinden (MPa) kaydedildi ve kopma tipleri değerlendirildi. İstatistiksel farklılıklar tek yönlü ANOVA ve Tukey’s testi ile p<0,05 düzeyinde uygulandı.

Bulgular: Uygulanan tüm jeller KON grubuna kıyasla  daha  düşük  MGBD   değerleri   oluşturdu. Jeller arasında ise farklılık saptanmadı; CEG>COG>GEG>FOB (p>0,05). Kontrol grubunda karışık kopma tipi baskın olarak görülürken diğer tüm gruplarda adeziv kopma tipi görüldü. Sonuç: Bu tip jellerin antibakteriyel özelliklerinin yanı sıra kullanımları sırasında mikro-mekanik bağlantı ve klinik performanslarına ait değişiklikler göz ardı edilmemelidir.

Keywords

Kavite dezenfektanı antibakteriyel jel mikro-gerilme bağlanma dayanımı.

References

  • Brännström M. The cause of postrestorative sensitivity and its prevention. J Endod. 1986; 12: 475-81.
  • Murray PE, Hafez AA, Smith AJ, Cox CF. Bacterial microleakage and pulp inflammation associated with various restorative materials. Dent Mater 2002; 18: 470-8.
  • Fardal O, Turnbull RS. A review of the literature on use of chlorhexidine in dentistry. J
  • Am Dent Assoc 1986; 112: 863-9.
  • Meiers JC, Kresin JC. Cavity disinfectants and dentin bonding. Oper Dent 1996; 21: 153-9.
  • Ergücü Z, Hiller KA, Schmalz G. Influence of dentin on the effectiveness of antibacterial agents. J Endod 2005; 31: 124-9.
  • Kandaswamy D, Venkateshbabu N, Gogulnath D, Kindo AJ. Dentinal tubule disinfection with 2% chlorhexidine gel, propolis, morinda citrifolia juice, 2% povidone iodine, and calcium hydroxide. Int Endod J 2010; 43: 419-23.
  • Signoretti FG, Gomes BP, Montagner F, Barrichello Tosello F, Jacinto RC. Influnce of 2% chlorhexidine gel on calcium hydroxide ionic dissociation and its ability of reducing endotoxin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 111: 653-8.
  • Lessa FC, Nogueira I, Vargas Fda S, Spolidorio DM, Hebling J, García-Godoy F, Costa CA. Direct and transdentinal antibacterial activity of chlorhexidine. Am J Dent 2010; 23: 255-59.
  • Ersin NK, Eden E, Eronat N, Totu FI, Ates M. Effectiveness of 2-year application of school-based chlorhexidine varnish, sodium fluoride gel, and dental health education programs in high-risk adolescents. Quintessence Int 2008; 39: e45-51.
  • Lindquist B, Gisselsson H, Wennerholm K. Effect of chlorhexidine gel on approximal caries increment in adolescents with high caries risk using professional flossing compared to individual trays. Swed Dent J 2010; 34: 17-25.
  • Lessa FC, Aranha AM, Nogueira I, Giro EM, Hebling J, Costa CA. Toxicity of chlorhexidine on odontoblast-like cells. Journal Appl Oral Sci 2010; 8: 50-8.
  • Lessa FC, Nogueira I, Huck C, Hebling J & Costa CA. Transdentinal cytotoxic effects of different concentrations of chlorhexidine gel applied on acid-conditioned dentin substrate. J Biomed Mater Res B Appl Biomater 2010; 92: 40-7.
  • Valera MC, da Rosa JA, Maekawa LE, de Oliveira LD, Carvalho CA, Koga-Ito CY, Jorge AO. Action of propolis and medications against Escherichia coli and endodoxin in root canals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 110: e70-4.
  • Uzel A, Sorkun K, Onçağ O, Cogulu D, Gençay O, Salih B. Chemical compositions and antimicrobial activities of four different Anatolian propolis samples. Microbiol Res 2005; 160: 189-95.
  • Gopikrishna V, Baweja PS, Venkateshbabu N, Thomas T, Kandaswamy D. Comparison of coconut water, propolis, HBSS, and milk on PDL cell survival. J Endod 2008; 34: 587-9.
  • George D, Bhat SS, Antony B. Comparative evaluation of the antimicrobial efficacy of aloe vera tooth gel and two popular commercial toothpastes: an in vitro study. Gen Dent 2009; 57: 238-41.
  • Al-Bayaty FH, Taiyeb-Ali TB, Abdulla MA & Mahmud ZB. Antibacterial effects of Oradex, Gengigel and Salviathymol-n mouthwash on dental biofilm bacteria. African Journal of Microbology Research 2011; 5: 636-42.
  • Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A & Bernard GW. Bacteriostatic effects of hyaluronic acid. J Periodontol 1999; 70: 370-74.
  • Ardizzoni A, Neglia RG, Baschieri MC, Cermelli C, Caratozzolo M, Righi E, Palmieri B, Blasi E. Influence of hyaluronic acid on bacterial and fungal species, including clinically relevant opportunistic pathogens. J Mater Sci Mater Med 2011; 22: 2329-38.
  • Inuyama Y, Kitamura C, Nishihara T, Morotomi T, Nagayoshi M, Tabata Y, Matsuo K, Chen KK, Terashita M. Effects of hyaluronic acid sponge as a scaffold on odontoblastic cell line and amputated dental pulp. J Biomed Mater Res B Appl Biomater 2010; 92: 120-128.
  • Gürgan S, Bolay S, Kiremitçi A. Effect of disinfectant application methods on the bond strength of composite to dentin. J Oral Rehabil 1999; 26: 836-40.
  • Meiers JC, Shook LW. Effect of disinfectants on the bond strength of composite to dentin. Am J Dent 1996; 9: 11-4.
  • Perdigao J, Denehy GE, Swift EJ. Effects of chlorhexidine on dentin surfaces and shear bond strengths. Am J Dent 1994; 7: 81-4.
  • Say EC, Koray F, Tarim B, Soyman M, Gülmez T. In vitro effect of cavity disinfectants on the bond strength of dentin bonding systems. Quintessence Int 2004; 35: 56-60.
  • Hebling J, Pashley DH, Tjaderhane L, Tay FR. Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo. J Dent Res 2005; 84: 741-6.
  • Castro FL, de Andrade MF, Duarte Júnior SL, Vaz LG, Ahid FJ. Effect of 2% chlorhexidine on microtensile bond strength of composite to dentin. J Adhes Dent 2003; 5: 129-38.
  • Pashley DH,Sano H, Ciucchi B, Yoshiyma M, Carvalho RM. Adhesion testing of dentin bonding agents: a review. 1995; 11: 117-25.
  • Pashley DH, Carvalho RM, Sano H, Nakajima M, Yoshiyama M, Shono Y, Fernandes CA, Tay F. The microtensile bond test: a review. J Adhes Dent 1999; 1: 299-309.
  • Schreiner R, Chappell R;eick J. Microtensile testing of dentin adhesives. Dent Mater 1998; 14:194-201.
  • Tay FR, Gwinnett JA, Wei SHY. The overwet phenomenon: a transmission electron microscopic study of surface moisture in the acid-condtioned,resin-dentin interface. Am J Dent 1996; 9: 161-166.

Kavite dezenfeksiyonu amacı ile kullanılabilen ticari antibakteriyel jellerin mikro- gerilme bağlanma dayanımı üzerine etkinliklerinin değerlendirilmesi

Year 2012, Volume: 15 Issue: 4, 288 - 296, 17.04.2012

Tamer Tüzüner , Ayça Ulusoy , Ozgul Baygin , Görkem Yahyaoğlu İlkay Yalçın

https://doi.org/10.7126/cdj.2012.1510
Cited By: 2

Abstract

Amaç: Çürüğün yeterli temizlenmemesi sonucu kavite içerisinde geride kalan bakteri miktarı restoratif diş hekimliğinde sorun oluşturmaktadır. Pulpa kaplaması veya kaide materyali uygulanımı öncesi kavite dezenfeksiyonu önerilmektedir. Bu çalışmanın amacı ticari olarak piyasada yer alan jel formülasyonlarının total etch bir kompozit sistemin mikro-gerilme bağlanma dayanımı (MGBD) üzerinde oluşturduğu etkinin değerlendirilmesidir.Gereç ve Yöntem: Ticari olarak piyasada yeralan klorheksidin [(Corsdoyl gel- %1KHXCOG), (Cervitec gel-%0,2 KHX+%0,2 sodyum fluorid-CEG), aleo vera (Forever Bright-FOB) ve hyaluronik asit (Gengigel-GEG) içerikli ticari antibakteriyel jel formülasyonları bu çalışmada kullanıldı. Kontrol grubunda ise (KON) herhangi bir dezenfektan uygulanmadı. Çalışmada her bir grup için 2 adet olmak üzere toplam 10 adet çekilmiş çürüksüz insan 3.molar dişi kullanıldı. Jel gruplarında total etch sistem uygulamanın ardından bonding materyalin kullanımından hemen önce 1 dakika süre ile jeller uygulandı, steril peletle ortamdan uzaklaştırıldı ve hava ile kurutuldu. Daha sonra kompozit restorasyonlar yapıldı. 24 saat süre ile 370C’de distile suda saklanan örneklerden her bir grupta 10’ar adet olacak şekilde (kesit çapı 1,0±0,1 mm2) kompozit-dentin çubuk örnekleri oluşturuldu. Bu örnekler daha sonra dakikada 1 mm kuvvet uygulanarak MGBD testine tabi tutuldu. Kompozit-dentin arası bağlanma dayanım değerleri megapaskal cinsinden (MPa) kaydedildi ve kopma tipleri değerlendirildi. İstatistiksel farklılıklar tek yönlü ANOVA ve Tukey’s testi ile p

Keywords

Kavite dezenfektanı antibakteriyel dayanımı

References

  • Brännström M. The cause of postrestorative sensitivity and its prevention. J Endod. 1986; 12: 475-81.
  • Murray PE, Hafez AA, Smith AJ, Cox CF. Bacterial microleakage and pulp inflammation associated with various restorative materials. Dent Mater 2002; 18: 470-8.
  • Fardal O, Turnbull RS. A review of the literature on use of chlorhexidine in dentistry. J
  • Am Dent Assoc 1986; 112: 863-9.
  • Meiers JC, Kresin JC. Cavity disinfectants and dentin bonding. Oper Dent 1996; 21: 153-9.
  • Ergücü Z, Hiller KA, Schmalz G. Influence of dentin on the effectiveness of antibacterial agents. J Endod 2005; 31: 124-9.
  • Kandaswamy D, Venkateshbabu N, Gogulnath D, Kindo AJ. Dentinal tubule disinfection with 2% chlorhexidine gel, propolis, morinda citrifolia juice, 2% povidone iodine, and calcium hydroxide. Int Endod J 2010; 43: 419-23.
  • Signoretti FG, Gomes BP, Montagner F, Barrichello Tosello F, Jacinto RC. Influnce of 2% chlorhexidine gel on calcium hydroxide ionic dissociation and its ability of reducing endotoxin. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 111: 653-8.
  • Lessa FC, Nogueira I, Vargas Fda S, Spolidorio DM, Hebling J, García-Godoy F, Costa CA. Direct and transdentinal antibacterial activity of chlorhexidine. Am J Dent 2010; 23: 255-59.
  • Ersin NK, Eden E, Eronat N, Totu FI, Ates M. Effectiveness of 2-year application of school-based chlorhexidine varnish, sodium fluoride gel, and dental health education programs in high-risk adolescents. Quintessence Int 2008; 39: e45-51.
  • Lindquist B, Gisselsson H, Wennerholm K. Effect of chlorhexidine gel on approximal caries increment in adolescents with high caries risk using professional flossing compared to individual trays. Swed Dent J 2010; 34: 17-25.
  • Lessa FC, Aranha AM, Nogueira I, Giro EM, Hebling J, Costa CA. Toxicity of chlorhexidine on odontoblast-like cells. Journal Appl Oral Sci 2010; 8: 50-8.
  • Lessa FC, Nogueira I, Huck C, Hebling J & Costa CA. Transdentinal cytotoxic effects of different concentrations of chlorhexidine gel applied on acid-conditioned dentin substrate. J Biomed Mater Res B Appl Biomater 2010; 92: 40-7.
  • Valera MC, da Rosa JA, Maekawa LE, de Oliveira LD, Carvalho CA, Koga-Ito CY, Jorge AO. Action of propolis and medications against Escherichia coli and endodoxin in root canals. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 110: e70-4.
  • Uzel A, Sorkun K, Onçağ O, Cogulu D, Gençay O, Salih B. Chemical compositions and antimicrobial activities of four different Anatolian propolis samples. Microbiol Res 2005; 160: 189-95.
  • Gopikrishna V, Baweja PS, Venkateshbabu N, Thomas T, Kandaswamy D. Comparison of coconut water, propolis, HBSS, and milk on PDL cell survival. J Endod 2008; 34: 587-9.
  • George D, Bhat SS, Antony B. Comparative evaluation of the antimicrobial efficacy of aloe vera tooth gel and two popular commercial toothpastes: an in vitro study. Gen Dent 2009; 57: 238-41.
  • Al-Bayaty FH, Taiyeb-Ali TB, Abdulla MA & Mahmud ZB. Antibacterial effects of Oradex, Gengigel and Salviathymol-n mouthwash on dental biofilm bacteria. African Journal of Microbology Research 2011; 5: 636-42.
  • Pirnazar P, Wolinsky L, Nachnani S, Haake S, Pilloni A & Bernard GW. Bacteriostatic effects of hyaluronic acid. J Periodontol 1999; 70: 370-74.
  • Ardizzoni A, Neglia RG, Baschieri MC, Cermelli C, Caratozzolo M, Righi E, Palmieri B, Blasi E. Influence of hyaluronic acid on bacterial and fungal species, including clinically relevant opportunistic pathogens. J Mater Sci Mater Med 2011; 22: 2329-38.
  • Inuyama Y, Kitamura C, Nishihara T, Morotomi T, Nagayoshi M, Tabata Y, Matsuo K, Chen KK, Terashita M. Effects of hyaluronic acid sponge as a scaffold on odontoblastic cell line and amputated dental pulp. J Biomed Mater Res B Appl Biomater 2010; 92: 120-128.
  • Gürgan S, Bolay S, Kiremitçi A. Effect of disinfectant application methods on the bond strength of composite to dentin. J Oral Rehabil 1999; 26: 836-40.
  • Meiers JC, Shook LW. Effect of disinfectants on the bond strength of composite to dentin. Am J Dent 1996; 9: 11-4.
  • Perdigao J, Denehy GE, Swift EJ. Effects of chlorhexidine on dentin surfaces and shear bond strengths. Am J Dent 1994; 7: 81-4.
  • Say EC, Koray F, Tarim B, Soyman M, Gülmez T. In vitro effect of cavity disinfectants on the bond strength of dentin bonding systems. Quintessence Int 2004; 35: 56-60.
  • Hebling J, Pashley DH, Tjaderhane L, Tay FR. Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo. J Dent Res 2005; 84: 741-6.
  • Castro FL, de Andrade MF, Duarte Júnior SL, Vaz LG, Ahid FJ. Effect of 2% chlorhexidine on microtensile bond strength of composite to dentin. J Adhes Dent 2003; 5: 129-38.
  • Pashley DH,Sano H, Ciucchi B, Yoshiyma M, Carvalho RM. Adhesion testing of dentin bonding agents: a review. 1995; 11: 117-25.
  • Pashley DH, Carvalho RM, Sano H, Nakajima M, Yoshiyama M, Shono Y, Fernandes CA, Tay F. The microtensile bond test: a review. J Adhes Dent 1999; 1: 299-309.
  • Schreiner R, Chappell R;eick J. Microtensile testing of dentin adhesives. Dent Mater 1998; 14:194-201.
  • Tay FR, Gwinnett JA, Wei SHY. The overwet phenomenon: a transmission electron microscopic study of surface moisture in the acid-condtioned,resin-dentin interface. Am J Dent 1996; 9: 161-166.
There are 31 citations in total.

Details

Primary Language English
Journal Section Original Research Articles
Authors

Tamer Tüzüner

Ayça Ulusoy

Ozgul Baygin

Görkem Yahyaoğlu

İlkay Yalçın

Publication Date April 17, 2012
Submission Date April 17, 2012
Published in Issue Year 2012Volume: 15 Issue: 4

Cite

EndNote Tüzüner T, Ulusoy A, Baygin O, Yahyaoğlu G, Yalçın İ (October 1, 2012) Kavite dezenfeksiyonu amacı ile kullanılabilen ticari antibakteriyel jellerin mikro-gerilme bağlanma dayanımı üzerine etkinliklerinin değerlendirilmesi. Cumhuriyet Dental Journal 15 4 288–296.

Cited By

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DERİN DENTİN ÇÜRÜKLERİNİN TEDAVİSİNDE ALTERNATİF YENİ YÖNTEMLER
Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi
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https://doi.org/10.17567/ataunidfd.290602

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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