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Von Willebrand hastalığı’nda oral cerrahi yaklaşım: olgu sunumu

Year 2008, Volume: 11 Issue: 1, 45 - 48, 11.11.2011

Ediz Deniz Ahmet Arslan

Abstract

Von Willebrand Disease (VWD) is a hereditary coagulation disorder characterized by a deficient or abnormal plasma protein known as the von Willebrand factor (vWF). Patients with VWD usually manifest a dual hemostatic defect characterized by a prolonged bleeding time and low plasma levels of Factor VIII coagulant activity. In the present case, management of 39 years old female patient with VWD in whom cryoprecipitate transfusion was applied for multiple tooth extractions was reported and alternative treatment protocols were discussed.

ÖZET

Von Willebrand Hastalığı (VWH), von Willebrand faktör (vWF) olarak bilinen plazma proteinin yetersiz ya da anormal şekilde bulunması ile karakterize herediter koagülasyon bozukluğudur. VWH olan hastalar, genellikle uzamış kanama zamanı ve Faktör VIII koagülasyon aktivitesinin düşük plazma değerleri ile karakterize ikili  bir hemostatik defekte sahiptirler. Bu olgu raporunda, kliniğimize VWH tanısı ile başvuran 39 yaşındaki bayan hastanın, kriyospitat replasman tedavisi ile çoklu diş çekimleri gerçekleştirilip, alternatif tedavi protokolleri tartışılmıştır.

Anahtar kelimeler: Von Willebrand Hastalığı, diş çekimi

Keywords

Von Willebrand Disease; tooth extraction

References

  • 1. Wilde JT, Cook RJ. Von Willebrand Disease and its management in oral and maxillofacial surgery. Br J Oral Maxillofac Surg 1998; 36(2): 112-118.
  • 2. Ghom AG. Textbook of Oral Medicine. 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2005. p. 806.
  • 3. Federici AB, Castaman G, Thompson A, Berntorp E. Von Willebrand's disease: clinical management. Haemophilia 2006; 12(3): 152-158.
  • 4. Joseph RR. Hematologic Disorders. In: Rose FL, Kaye D. Internal Medicine For Dentistry. St. Louis: The C.V. Mosby Company;1983. p. 407-408.
  • 5. Mannucci PM, Chediak J, Hanna W, Byrnes J, Ledford M, Ewenstein BM, Retzios AD, Kapelan BA, Schwartz RS, Kessler C, and Alphanate Study Group. Treatment of von Willebrand disease with a high-purity factor VIII/von Willebrand factor concentrate: a prospective, multicenter study. Blood 2002; 99(2): 450-456.
  • 6. Rodeghiero F, Castaman G, Dini E. Epidemiological investigation of the prevalence of von Willebrand’s disease. Blood 1987; 69: 454-459.
  • 7. Werner EJ, Broxson EH, Tucker EL, Giroux DS, Shults J, Abshire TC. Prevalence of von Willebrand disease in children: a multiethnic study. J Pediatr 1993; 123: 893-898.
  • 8. Israels S, Schwetz N, Boyar R, McNicol A. Bleeding disorders: characterization, dental considerations and management. J Can Dent Assoc 2006; 72(9): 827-827L.
  • 9. Franchini M, Rossetti G, Tagliaferri A, Pattacini C, Pozzoli D, Lorenz C, Del Dot L, Ugolotti G, Dell’aringa C, Gandini G. Dental procedures in adult patients with hereditary bleeding disorders: 10 years experience in three Italian Hemophilia Centers. Haemophilia 2005; 11(5): 504-509.
  • 10. Morimoto Y, Yoshioka A, Sugimoto M, Imai Y, Kirita T. Haemostatic management of intraoral bleeding in patients with von Willebrand disease. Oral Dis. 2005; 11(4): 243-248.
  • 11. Piot B, Sigaud-Fiks M, Huet P, Fressinaud E, Trossaërt M, Mercier J. Management of dental extractions in patients with bleeding disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93(3): 247-250.

VON WILLEBRAND HASTALIĞI’NDA ORAL CERRAHİ YAKLAŞIM: OLGU SUNUMU

Year 2008, Volume: 11 Issue: 1, 45 - 48, 11.11.2011

Ediz Deniz Ahmet Arslan

Abstract

Von Willebrand Hastalığı (VWH), von Willebrand faktör (vWF) olarak bilinen plazma proteinin yetersiz ya da anormal şekilde bulunması ile karakterize herediter koagülasyon bozukluğudur. VWH olan hastalar, genellikle uzamış kanama zamanı ve Faktör VIII koagülasyon aktivitesinin düşük plazma değerleri ile karakterize ikili bir hemostatik defekte sahiptirler. Bu olgu raporunda, kliniğimize VWH tanısı ile başvuran 39 yaşındaki bayan hastanın, kriyospitat replasman tedavisi ile çoklu diş çekimleri gerçekleştirilip, alternatif tedavi protokolleri tartışılmıştır

Keywords

Von Willebrand Hastalığı diş çekimi

References

  • 1. Wilde JT, Cook RJ. Von Willebrand Disease and its management in oral and maxillofacial surgery. Br J Oral Maxillofac Surg 1998; 36(2): 112-118.
  • 2. Ghom AG. Textbook of Oral Medicine. 1st ed. New Delhi: Jaypee Brothers Medical Publishers; 2005. p. 806.
  • 3. Federici AB, Castaman G, Thompson A, Berntorp E. Von Willebrand's disease: clinical management. Haemophilia 2006; 12(3): 152-158.
  • 4. Joseph RR. Hematologic Disorders. In: Rose FL, Kaye D. Internal Medicine For Dentistry. St. Louis: The C.V. Mosby Company;1983. p. 407-408.
  • 5. Mannucci PM, Chediak J, Hanna W, Byrnes J, Ledford M, Ewenstein BM, Retzios AD, Kapelan BA, Schwartz RS, Kessler C, and Alphanate Study Group. Treatment of von Willebrand disease with a high-purity factor VIII/von Willebrand factor concentrate: a prospective, multicenter study. Blood 2002; 99(2): 450-456.
  • 6. Rodeghiero F, Castaman G, Dini E. Epidemiological investigation of the prevalence of von Willebrand’s disease. Blood 1987; 69: 454-459.
  • 7. Werner EJ, Broxson EH, Tucker EL, Giroux DS, Shults J, Abshire TC. Prevalence of von Willebrand disease in children: a multiethnic study. J Pediatr 1993; 123: 893-898.
  • 8. Israels S, Schwetz N, Boyar R, McNicol A. Bleeding disorders: characterization, dental considerations and management. J Can Dent Assoc 2006; 72(9): 827-827L.
  • 9. Franchini M, Rossetti G, Tagliaferri A, Pattacini C, Pozzoli D, Lorenz C, Del Dot L, Ugolotti G, Dell’aringa C, Gandini G. Dental procedures in adult patients with hereditary bleeding disorders: 10 years experience in three Italian Hemophilia Centers. Haemophilia 2005; 11(5): 504-509.
  • 10. Morimoto Y, Yoshioka A, Sugimoto M, Imai Y, Kirita T. Haemostatic management of intraoral bleeding in patients with von Willebrand disease. Oral Dis. 2005; 11(4): 243-248.
  • 11. Piot B, Sigaud-Fiks M, Huet P, Fressinaud E, Trossaërt M, Mercier J. Management of dental extractions in patients with bleeding disorders. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 93(3): 247-250.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Reports
Authors

Ediz Deniz

Ahmet Arslan

Publication Date November 11, 2011
Submission Date November 11, 2011
Published in Issue Year 2008Volume: 11 Issue: 1

Cite

EndNote Deniz E, Arslan A (November 1, 2011) Von Willebrand hastalığı’nda oral cerrahi yaklaşım: olgu sunumu. Cumhuriyet Dental Journal 11 1 45–48.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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