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İmplantolojide doku mühendisliği ve gen tedavisi

Year 2011, Volume: 14 Issue: 1, 64 - 68, 22.01.2011

Abstract

Son elli yılda implantoloji alanında büyük adımlar atılmıştır. Günümüzde implantın kemik ile bağlantısı kabul edilebilir derecede başarılı olmasına rağmen inflamasyon, trombozis, fibrozis ve enfeksiyon gibi komplikasyonlar görülebilmektedir. Genetik ve doku mühendisliği alanındaki gelişmelerle birlikte ileri çalışmalara ihtiyaç duyulmaktadır. Görülen komplikasyonları en aza indirmek için implantın yerleştirildiği dokunun yanıtının istenilen düzeyde ve şekilde olması ve immün reaksiyonun düzenlenmesi gerekmektedir. Ayrıca yerleştirilmesi için, kaybedilen alveolar kemik dokusunun genişletilmesi mümkün hale gelmiştir

References

  • Nerem R, Sambanis A. Tissue engineering from biology to biological substitutes. Tissue Eng 1995;1:3-13.
  • Baum BJ, Mooney DJ. The impact of tissue engineering on dentistry. J Am Dent Assoc 2000;131:309-318.
  • Jin QM, Zhao M, Webb SA, Berry JE, Somerman MJ, Giannobile WV. Cementum engineering with three- dimensional polymer scaffolds. J Biomed Mater Res A 2003;67:54-60.
  • Kaigler D, Mooney D. Tissue engineering's impact on dentistry. J Dent Educ 2001;65:456-462.
  • Dinçkan N. Diş Hekimliğinde Doku Mühendisliğinin Üniversitesi Diş Hekimliği Fakültesi Bitirme Tezi, 2008. Etkileri. İstanbul
  • Scheller EL, Krebsbach PH, Kohn DH. Tissue engineering: state of the art in oral rehabilitation. J Oral Rehabil 2009;36:368-389.
  • Baum BJ, Mooney DJ. The impact of tissue engineering on dentistry. J Am Dent Assoc 2000;131:309-318.
  • Caudill RF. Guided bone regeneration and implants: history and case reports. In: Block MS, Kent JN, Guerra LR, eds. Implants in dentistry. Philadelphia: Saunders; 1997:183-191.
  • Becker W. Guided tissue regeneration for periodontal defects. In: Polson AM, ed. Periodontal regeneration: current status Quintessence Publishing; 1994:137- 150. Chicago:
  • Tamura RN, Oda D, Quaranta V, et al. Coating of titanium alloy with soluble laminin-5 promotes cell attachment and hemidesmosome assembly in gingival epithelial cells: potential application to dental implants. J Periodontol Res 1997;32:287-294.
  • Morrison G. Advances in the skin trade. Mechanical Eng 1999;121:40-43.
  • Moradian-Oldak J, Wen HB, Schneider GB, Stanford CM. Tissue engineering strategies for the future generation of dental implants. Periodontol 2000 2006;41:157-176.
  • Ratner BD. Replacing and renewing: synthetic materials, biomimetics, and tissue engineering in implant dentistry. J Dent Educ 2001;65:1340-1347.
  • Dee KC, Puleo, Bizios R. Engineering of applications. Mater Today 2000;3:7-10. for biomedical
  • Chen F, Ouyang H, Feng X, Gao Z, Yang Y, Zou X, Liu T, Zhao G, Mao T. Anchoring dental implant in tissue- engineered bone using composite scaffold: a preliminary study in nude mouse model. J Oral Maxillofac Surg 2006;63:586-591.
  • Ito K, Yamada Y, Naiki T, Ueda M. Simultaneous implant placement and bone regeneration around dental implants using tissue-engineered bone with fibrin glue, mesenchymal stem cells and platelet-rich plasma. Clin Oral Implants Res 2006;17:579-586.
  • Yamada Y, Ueda M, Naiki T, Nagasaka injectable bone regeneration for osseointegrated dental implants. Clin Oral Implants Res 2004;15:589-597.
  • Marei MK, Nouh SR, Saad MM, Ismail NS. Preservation and regeneration of alveolar bone by tissue-engineered implants. Tissue Eng 2005;11:751-767.
  • Dunn CA, Jin Q, Taba M Jr, Franceschi RT, Bruce Rutherford R, Giannobile WV. BMP gene delivery for alveolar bone engineering at dental implant 2005;11:294-299. Mol Ther
  • Schmelzeisen R, Schimming R, Sittinger M. Making bone: implant insertion into tissue-engineered bone for maxillary sinus floor augmentation- a Craniomaxillofac Surg 2003;31:34-39.
  • Ueda M, Tohnai I, Nakai H. Tissue engineering research in oral implant surgery. Artif Organs 2001;25:164- 171.

Tissue engineering and gene therapy in implantology

Year 2011, Volume: 14 Issue: 1, 64 - 68, 22.01.2011

Abstract

In the last fifty years great strides have been made in implantology. Recently, although implant and bone connection has an acceptable success, complications such as inflammation, fibrosis,
thrombosis and infection still remains. With the progression in genetics and tissue engineering, advanced studies are needed. Tissue response of implant-bone contact area must be in a desired level and immune reactions must be promoted for complications to be minimized. Also remodeling or enlargement of alveolar bone for placement of implant becomes possible with tissue engineering. 

References

  • Nerem R, Sambanis A. Tissue engineering from biology to biological substitutes. Tissue Eng 1995;1:3-13.
  • Baum BJ, Mooney DJ. The impact of tissue engineering on dentistry. J Am Dent Assoc 2000;131:309-318.
  • Jin QM, Zhao M, Webb SA, Berry JE, Somerman MJ, Giannobile WV. Cementum engineering with three- dimensional polymer scaffolds. J Biomed Mater Res A 2003;67:54-60.
  • Kaigler D, Mooney D. Tissue engineering's impact on dentistry. J Dent Educ 2001;65:456-462.
  • Dinçkan N. Diş Hekimliğinde Doku Mühendisliğinin Üniversitesi Diş Hekimliği Fakültesi Bitirme Tezi, 2008. Etkileri. İstanbul
  • Scheller EL, Krebsbach PH, Kohn DH. Tissue engineering: state of the art in oral rehabilitation. J Oral Rehabil 2009;36:368-389.
  • Baum BJ, Mooney DJ. The impact of tissue engineering on dentistry. J Am Dent Assoc 2000;131:309-318.
  • Caudill RF. Guided bone regeneration and implants: history and case reports. In: Block MS, Kent JN, Guerra LR, eds. Implants in dentistry. Philadelphia: Saunders; 1997:183-191.
  • Becker W. Guided tissue regeneration for periodontal defects. In: Polson AM, ed. Periodontal regeneration: current status Quintessence Publishing; 1994:137- 150. Chicago:
  • Tamura RN, Oda D, Quaranta V, et al. Coating of titanium alloy with soluble laminin-5 promotes cell attachment and hemidesmosome assembly in gingival epithelial cells: potential application to dental implants. J Periodontol Res 1997;32:287-294.
  • Morrison G. Advances in the skin trade. Mechanical Eng 1999;121:40-43.
  • Moradian-Oldak J, Wen HB, Schneider GB, Stanford CM. Tissue engineering strategies for the future generation of dental implants. Periodontol 2000 2006;41:157-176.
  • Ratner BD. Replacing and renewing: synthetic materials, biomimetics, and tissue engineering in implant dentistry. J Dent Educ 2001;65:1340-1347.
  • Dee KC, Puleo, Bizios R. Engineering of applications. Mater Today 2000;3:7-10. for biomedical
  • Chen F, Ouyang H, Feng X, Gao Z, Yang Y, Zou X, Liu T, Zhao G, Mao T. Anchoring dental implant in tissue- engineered bone using composite scaffold: a preliminary study in nude mouse model. J Oral Maxillofac Surg 2006;63:586-591.
  • Ito K, Yamada Y, Naiki T, Ueda M. Simultaneous implant placement and bone regeneration around dental implants using tissue-engineered bone with fibrin glue, mesenchymal stem cells and platelet-rich plasma. Clin Oral Implants Res 2006;17:579-586.
  • Yamada Y, Ueda M, Naiki T, Nagasaka injectable bone regeneration for osseointegrated dental implants. Clin Oral Implants Res 2004;15:589-597.
  • Marei MK, Nouh SR, Saad MM, Ismail NS. Preservation and regeneration of alveolar bone by tissue-engineered implants. Tissue Eng 2005;11:751-767.
  • Dunn CA, Jin Q, Taba M Jr, Franceschi RT, Bruce Rutherford R, Giannobile WV. BMP gene delivery for alveolar bone engineering at dental implant 2005;11:294-299. Mol Ther
  • Schmelzeisen R, Schimming R, Sittinger M. Making bone: implant insertion into tissue-engineered bone for maxillary sinus floor augmentation- a Craniomaxillofac Surg 2003;31:34-39.
  • Ueda M, Tohnai I, Nakai H. Tissue engineering research in oral implant surgery. Artif Organs 2001;25:164- 171.
There are 21 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Review
Authors

Meltem Özdemir Karataş

Didem Özdemir Özenen

Ali Balık

Erman Tuncer

Publication Date January 22, 2011
Submission Date December 5, 2009
Published in Issue Year 2011Volume: 14 Issue: 1

Cite

EndNote Özdemir Karataş M, Özdemir Özenen D, Balık A, Tuncer E (January 1, 2011) İmplantolojide doku mühendisliği ve gen tedavisi. Cumhuriyet Dental Journal 14 1 64–68.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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