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COMBINED TREATMENT OF A LARGE AGGRESSIVE CENTRAL GIANT CELL GRANULOMA

Year 2017, Volume: 20 Issue: 2, 117 - 121, 31.08.2017
https://doi.org/10.7126/cumudj.345921

Abstract

Central giant cell tumours are rare, accounting for less than 7% of all jaw
tumours. These tumours are usually observed in women, occur most often in the
mandible, and are more common in the second decade of life. Treatment consists
of local removal, partial resection, or total resection. In this case, a
32-year-old female patient presented in our clinic with pain in the anterior
mandible. No cervical lymphadenopathy was detected upon physical examination. No
ulceration was observed during the intraoral examination, but sensitivity was found
in the vestibular area. However, no sensation loss in any teeth or in the lips
was detected. This case report presents a 32-year-old female patient with
central giant cell tumour causing extensive bone loss in the mandible base that
was treated with partial resection.

References

  • 1. Hutter RVP,Worcester JNJr, Francis KC, Foote FW Jr Stewart FW. Benign and malignant giant cell tumors of bone. Cancer 1962;15:653-90.
  • 2. Jaffe HL. Giant cell reparative granuloma, traumatic bone cyst and fibrous (fibro-osseous) dysplasia of the jaw bones. Oral Surg1953;6:159-75.
  • 3. Ustundag E, Iseri M, Keskin G, Müezzinoglu B. Central giant cell granuloma: case report. Int J Pediatr Otorhinolaryngol2002;65:143-6.
  • 4. Shirani G, Amir Abbasi J, Siimin Mohebbi Z, Shirinbak I.Management of a locally invasive central giant cell granuloma (CGCG) of mandible: report of an extraordinary large case. J Craniomaxillofac Surg 2011;39:530-3.
  • 5. Arda HN, Karakus MF, Ozcan M, Arda N, Gun T. Giant cell reparative granuloma originating from the ethmoid sinus. Int. J. Pediatr. Otorhinolaryngol. 2003;67:83-7.
  • 6. Batsakis JG.Clinical and pathological considerations, in: Tumors of the Head and Neck, Second ed., Williams & Wilkins, Baltimore, 1979.
  • 7. Som PM, Lawson W, Cohen BA. Giant-cell lesions of the facial bones, Radiology 1983;147:129-34.
  • 8. Sezer B, Koyuncu B, Gomel M, Günbay T. Intralesional corticosteroid injection for central giant cell granuloma: a case report and review of the literature, Turk J. Pediatr. 2005;47:75-81.
  • 9. Stern M, Eisenbud L. Management of giant cell lesions of the jaws, Oral. Maxillofac. Surg. Clin. North. Am. 1991;3:165-71.
  • 10. Jacoway JR, Howell FV, Terry BC. Central giant cell granuloma: an alternative to surgical therapy. Oral Surg 1988;66:572-6.

Büyük Agresif Bir Santral Dev Hücreli Granuloma Birlikte Tedavisi

Year 2017, Volume: 20 Issue: 2, 117 - 121, 31.08.2017
https://doi.org/10.7126/cumudj.345921

Abstract

Santral Dev Hücreli tümörler; çene tümörleri içinde kadınlarda
ve mandibulada sık görülürler ve yaşamın ikinci dekatında daha sıktırlar. Tedavisinde
lokal küretaj, parsiyel rezeksiyon ve total rezeksiyon uygulanabilir. Bu vaka
raporunda 32 yaşında kadın hasta anterior mandibulada ağrı şikayetiyle
kliniğimize başvurdu. Fiziksel muayenede servikal lenfadenopati saptanmadı. İntraorol
muayenede ülserasyon saptanmadı fakat vestibül bölgede hassasiyet mevcuttu. Bununla
beraber dişlerde ve dudakta his kaybı yoktu. Bu vaka raporunda 32 yaşında kadın
hastada mandibula basisinde yaygın kemik kaybına neden olan santral dev hücreli
tümörün parsiyel rezeksiyon ile tedavisi sunuldu. 

References

  • 1. Hutter RVP,Worcester JNJr, Francis KC, Foote FW Jr Stewart FW. Benign and malignant giant cell tumors of bone. Cancer 1962;15:653-90.
  • 2. Jaffe HL. Giant cell reparative granuloma, traumatic bone cyst and fibrous (fibro-osseous) dysplasia of the jaw bones. Oral Surg1953;6:159-75.
  • 3. Ustundag E, Iseri M, Keskin G, Müezzinoglu B. Central giant cell granuloma: case report. Int J Pediatr Otorhinolaryngol2002;65:143-6.
  • 4. Shirani G, Amir Abbasi J, Siimin Mohebbi Z, Shirinbak I.Management of a locally invasive central giant cell granuloma (CGCG) of mandible: report of an extraordinary large case. J Craniomaxillofac Surg 2011;39:530-3.
  • 5. Arda HN, Karakus MF, Ozcan M, Arda N, Gun T. Giant cell reparative granuloma originating from the ethmoid sinus. Int. J. Pediatr. Otorhinolaryngol. 2003;67:83-7.
  • 6. Batsakis JG.Clinical and pathological considerations, in: Tumors of the Head and Neck, Second ed., Williams & Wilkins, Baltimore, 1979.
  • 7. Som PM, Lawson W, Cohen BA. Giant-cell lesions of the facial bones, Radiology 1983;147:129-34.
  • 8. Sezer B, Koyuncu B, Gomel M, Günbay T. Intralesional corticosteroid injection for central giant cell granuloma: a case report and review of the literature, Turk J. Pediatr. 2005;47:75-81.
  • 9. Stern M, Eisenbud L. Management of giant cell lesions of the jaws, Oral. Maxillofac. Surg. Clin. North. Am. 1991;3:165-71.
  • 10. Jacoway JR, Howell FV, Terry BC. Central giant cell granuloma: an alternative to surgical therapy. Oral Surg 1988;66:572-6.
There are 10 citations in total.

Details

Subjects Health Care Administration
Journal Section Case Reports
Authors

Mahmut Koparal

Hilal Alan

K.serkan Ağaçayak

İ.halil Erdoğdu

Belgin Gulsun

Publication Date August 31, 2017
Submission Date October 23, 2017
Published in Issue Year 2017Volume: 20 Issue: 2

Cite

EndNote Koparal M, Alan H, Ağaçayak K, Erdoğdu İ, Gulsun B (August 1, 2017) COMBINED TREATMENT OF A LARGE AGGRESSIVE CENTRAL GIANT CELL GRANULOMA. Cumhuriyet Dental Journal 20 2 117–121.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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