A STUDY ON THE USE OF DIFFERENT MATERIALS COMBINED WITH ALLOGRAFT ON OSSEOINTEGRATION AND BONE REGENERATION OF DENTAL IMPLANTS WITH CORONAL DEFECTS IN A RABBIT MODEL

Oğuzhan Mehmet Elmalı; İlknur Eninanç; Defne Yeler; Ceylan Hepokur; Yener Ünal; Hasan Yeler

doi:10.7126/cumudj.712055

EN

A STUDY ON THE USE OF DIFFERENT MATERIALS COMBINED WITH ALLOGRAFT ON OSSEOINTEGRATION AND BONE REGENERATION OF DENTAL IMPLANTS WITH CORONAL DEFECTS IN A RABBIT MODEL

Abstract

Objectives: To assess differential effects of different materials combined with allograft on bone-to-implant contact and newly formed bone formation in dental implants with coronal defects histomorphometrically. Materials and Methods: The study was conducted on 24 male New Zealand white rabbits. Dental implants (3.0 × 10 mm) were placed at the center of defects (9 mm diameter, 4 mm depth) created in the tibial bones of the rabbits. Graft (GF, n=8), graft + rifamycin (GR, n=8), and graft + black cumin oil via orogastric route (GB, n=8) were applied on the coronal aspects of the implants for 28 days. Undecalcified histomorphometric analyses were conducted on slides stained with toluidine blue. Results: Bone-to-implant contact was 46.57% ± 3.59% in the graft, 67.12% ± 3.64% in the graft+rifamycin, and 55.62% ± 4.37% in the graft+black cumin oil groups. The percentage of new bone formation at the defect area was 34.71% ± 4.11% in the graft, 55.37% ± 4.89% in the graft + rifamycin, and 45.75% ± 3.69% in the graft + black cumin oil groups. In terms of new bone formation and bone-to-implant contact, graft + rifamycin and graft + black cumin oil groups were significantly different from the graft group. The differences between the graft + rifamycin and graft + black cumin oil groups were also statistically significant. Conclusion: Allogreft + rifamycin and orogastric black cumin oil were found to have positive effects on bone healing at sites with coronal defects. Rifamycin showed significantly greater favorable effects on bone-to-implant contact and new bone formation compared to black cumin oil.

Keywords

Supporting Institution

Scientific Research Project Fund of Sivas Cumhuriyet University (CÜBAP)

Project Number

DIS-158

Thanks

The authors thank Dr. Erdem KILIÇ from the Erciyes University Oral and Maxillofacial Surgery Department for his support in the research laboratory work.

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Oğuzhan Mehmet Elmalı
0000-0001-6054-0058
Türkiye

İlknur Eninanç
0000-0002-4583-6237
Türkiye

Defne Yeler
0000-0003-4801-0120
Türkiye

Ceylan Hepokur
0000-0001-6397-1291
Türkiye

Yener Ünal
0000-0002-4796-8276
Türkiye

Hasan Yeler ^*
0000-0003-0963-7350
Türkiye

Publication Date

October 5, 2020

Submission Date

April 9, 2020

Acceptance Date

August 26, 2020

Published in Issue

Year 2020 Volume: 23 Number: 3

DOI

https://doi.org/10.7126/cumudj.712055

IZ

https://izlik.org/JA62FH84SE

Cite

RIS / Bibtex

EndNote

Elmalı OM, Eninanç İ, Yeler D, Hepokur C, Ünal Y, Yeler H (October 1, 2020) A STUDY ON THE USE OF DIFFERENT MATERIALS COMBINED WITH ALLOGRAFT ON OSSEOINTEGRATION AND BONE REGENERATION OF DENTAL IMPLANTS WITH CORONAL DEFECTS IN A RABBIT MODEL. Cumhuriyet Dental Journal 23 3 232–239.

Cited By

Histomorphometric Analysis of Osseointegrated Intraosseous Dental Implants Using Undecalcified Specimens: A Scoping Review

Biomimetics

https://doi.org/10.3390/biomimetics9110672

Histological evaluation of the effect of Nigella sativa on the healing of created bony defect in the animal jaw

Dental Journal

https://doi.org/10.20473/j.djmkg.v58.i1.p7-13

Öz

A STUDY ON THE USE OF DIFFERENT MATERIALS COMBINED WITH ALLOGRAFT ON OSSEOINTEGRATION AND BONE REGENERATION OF DENTAL IMPLANTS WITH CORONAL DEFECTS IN A RABBIT MODEL

Abstract

Keywords

Supporting Institution

Project Number

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Histomorphometric Analysis of Osseointegrated Intraosseous Dental Implants Using Undecalcified Specimens: A Scoping Review

Histological evaluation of the effect of Nigella sativa on the healing of created bony defect in the animal jaw