Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE)-A Precursor of Oral Squamous Cell Carcinoma?
Abstract
Traumatic ulcerative granuloma with stromal eosinophilia (TUGSE) is a benign, chronic, reactive, self-healing lesion. It is composed of abundant eosinophils and small lymphocytes. Several studies have shown varying observations on the relation of tissue eosinophilia with the prognosis of oral cancer. Here, we present a case of a 65-year-old male who presented with a non-healing ulcer on the lateral border of tongue, which was suggestive of TUGSE on histopathological examination. Patient was kept on strict monthly follow up and the second re-biopsy was suggestive of moderately differentiated squamous cell carcinoma. Literature does not support the transformation of TUGSE to oral squamous cell carcinoma; however, our experience suggests a close vigilance of such lesions due to its high clinical resemblance to malignancy. Hence, repeat biopsies on regular basis is mandatory in cases where the clinical picture is highly suspicious.
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Case Report
Authors
Ravindranath Vineetha
0000-0002-8932-9982
India
Keerthilatha M Pai
0000-0003-0967-5867
India
Abhay T Kamath
0000-0001-6412-3550
India
Chetana Chandrashekar
0000-0002-1061-0502
India
Publication Date
March 18, 2020
Submission Date
November 20, 2019
Acceptance Date
February 13, 2020
Published in Issue
Year 1970 Volume: 23 Number: 1