Research Article

Surgical management in patients with bisphosphonate-related osteonecrosis of the jaw: four cases

Volume: 1 Number: 1 December 5, 2014
EN TR

Surgical management in patients with bisphosphonate-related osteonecrosis of the jaw: four cases

Abstract

Bisphosphonates, which have been introduced into medicine in the early 1990’s, is now being used succesfully for treatment of primary osteolitic bone diseases such as metastathic diseases, multipl myeloma, paget disease, hypercalsemia in malingnancies and management of pain occuring in these bone pathologies. Their half-life in circulation is very short, but they can stay for years in bone tissue. On the other hand, reports about bisphosphonate-related osteonecrosis of the jaw has been increasingly published recently. In this case report, bisphosphonate-related osteonecrosis of the jaw and treatment modalities has been evaluated in four cases

Keywords

References

  1. Sharma D, Ivanovski S, Slevin M, Hamlet S, Pop TS, Brinzaniuc K, Petku EB, Miroiu RI. Bisphosphonate- related osteonecrosis of the jaw (BRONJ): Diagnostic criteria and possible pathogenic mechanisms of an unexpected anti-angiogenic side effect. Vasc Cell 2013; 5:1.
  2. Janovska Z. Bisphosphonate-related osteonecrosis of the jaws. A  severe side effect of bisphosphonate therapy. Acta Medica 2012; 55:111-115.
  3. Marx RE, Stern D. Oral and maxillofacial pathology: A rationale for treatment. 1st  ed. Illinois: Quintessence Publishing, 2002.
  4. Ruggiero SL, Fantasia J, Carlson  E. Bisphosphonate-related osteonecrosis of the jaw: Background and guidelines for diagnosis, staging and management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;102:433-441.
  5. Ergün S, Güneri P, Koca H. A new threat fort he jawbones: Bisphosphonates. Cumhuriyet Dent J 2008; 11:134-139.
  6. Hoefert S, Eufinger H. Necrosis of the jaws under bisphosphonate therapy. Orthopade 2006;35:204-209.
  7. Marx RE, Sawatari Y, Fortin M, Broumand V. Bisphosphonate- induced exposed bone (osteonecrosis/ osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J  Oral Maxillofac Surg 2005;63:1567-1575.
  8. Migliorati CA, Schubert MM, Peterson  B i s p h o s p h o n a t e - a s s o c i a t e d osteonecrosis of mandibular and maxillary bone: An emerging oral complication of supportive cancer therapy. Cancer 2005;104:83-93.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Ümit Karaçaylı

Publication Date

December 5, 2014

Submission Date

March 18, 2013

Acceptance Date

-

Published in Issue

Year 1970 Volume: 1 Number: 1

EndNote
Dikicier E, Karaçaylı Ü (December 1, 2014) Surgical management in patients with bisphosphonate-related osteonecrosis of the jaw: four cases. Cumhuriyet Dental Journal 1 1 11–15.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


CDJ accepts articles in English. Submitting a paper to CDJ is free of charges. In addition, CDJ has not have article processing charges.

Frequency: Four times a year (March, June, September, and December)

IMPORTANT NOTICE

All users of Cumhuriyet Dental Journal should visit to their user's home page through the "https://dergipark.org.tr/tr/user" " or "https://dergipark.org.tr/en/user" links to update their incomplete information shown in blue or yellow warnings and update their e-mail addresses and information to the DergiPark system. Otherwise, the e-mails from the journal will not be seen or fall into the SPAM folder. Please fill in all missing part in the relevant field.

Please visit journal's AUTHOR GUIDELINE to see revised policy and submission rules to be held since 2020.