Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
Abstract
Objectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content.
Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-adhering methacrylate-based (Vertise Flow) and a silorane-based (Filtek Silorane) composite resin were tested in the experiment. Ten cylindrical specimens were made of each material, using a mould (2mm. thick and 8 mm. in diameter). An agar diffusion method was employed, and cytotoxicity rankings were determined using lysis index scores. For statistical analysis, Kruskal-Wallis and Mann-Whitney U-tests were used.
Results: Amongst the composite resins, the silorane-based composite was found to be less cytotoxic than the methacrylate-based composite resins, which all had the same cytotoxicity ranking.
Conclusions: The silorane-based composite resin was considered more biocompatible than the methacrylate-based composite resins.
Keywords
References
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Details
Primary Language
English
Subjects
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Journal Section
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Publication Date
August 21, 2012
Submission Date
August 21, 2012
Acceptance Date
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Published in Issue
Year 2012 Volume: 15 Number: 4