The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites

Esra Ercan

doi:10.7126/cumudj.471947

EN

The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites

Abstract

Objective: Physiological changes start after tooth extraction. Some post-operative symptoms may accompany this healing period, and affect patient's life quality. Many techniques have been developed to promote healing soft and hard tissue and improve patient's life quality. So, the aim of this study was to compare the early soft tissue healing of extraction sites treated with leucocyte-platelet rich fibrin (L-PRF), titanium prepared platelet rich fibrin (T-PRF) and non-treated control sites.

Material&Methods:A total of 42 single root teeth were enrolled to study. Extraction site was treated by L-PRF or T-PRF. Spontanous healing sockets were considered as control sites. Landy Wound Healing Index (LWH) scores and H₂O₂ bubbling test results for complete wound epithelization (CWE) were recorded at 1^st and 2^nd week. Also, the patient was requested to record the VAS scale and the number of analgesics that taken during two days after extraction.

Results: The LWH were statistically significantly improved for all groups at 2^nd week according to 1^st week (p<0.05). However there was no difference among three groups in each week. According to H₂O₂ bubbling test results, the CWE ratio at 1st week was 7.1%, 53,3% and 69.2% of control, L-PRF and T-PRF groups, respectively. The control group rate of CWE was statistically significantly lower than both of the test groups (p<0.05). Both of the test groups at 2^nd week showed 100% CWE, however this rate was only 35.7% of control group. The VAS score, at 1^stday, was statistically significantly higher at control group than both of the test groups at first day (p<0.05). There was non-significant difference among groups at 2nd day. There wass also non-significant difference among groups with regard to number of analgesics.

Conclusion: Both T-PRF and L-PRF, which are completely autologous biomaterials, enhance wound epithelzation and reduced post-op discomfort at extraction sockets.

Keywords

tooth extraction,platelet-rich fibrin,wound healing

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Esra Ercan ^*
0000-0002-8696-4198
Türkiye

Publication Date

December 30, 2018

Submission Date

October 18, 2018

Acceptance Date

November 28, 2018

Published in Issue

Year 2018 Volume: 21 Number: 4

DOI

https://doi.org/10.7126/cumudj.471947

IZ

https://izlik.org/JA75EC37PK

Cite

RIS / Bibtex

EndNote

Ercan E (December 1, 2018) The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites. Cumhuriyet Dental Journal 21 4 304–310.