Diş Hekimliğinde Trombosit Konsantrasyonlarinin Tarihsel Gelişimi ve Özellikleri

Mehmet Kızıltoprak; Mustafa özay Uslu

doi:10.7126/cumudj.381546

TR EN

Diş Hekimliğinde Trombosit Konsantrasyonlarinin Tarihsel Gelişimi ve Özellikleri

Öz

Trombositler hemostaz ve yara iyileşmesinde çok önemli bir rol oynamakta ve ihtiva ettikleri büyüme faktörleri ve sitokinler sayesinde rejeneratif tedavinin potansiyel hücreleri arasında yer almaktadırlar. Bu durum, rejeneratif tedavide, trombosit ve trombosit konsantrasyonlarına olan ilgiyi arttırmıştır. Geçmişten günümüze kadar çeşitli trombosit konsantrasyonları elde edilmiş ve bu ürünler tek başına veya başka biomateryallerle kombine kullanıldığında, iyileşme sürecine olan olumlu katkıları görülmüştür. Trombosit konsantrasyonları, sert ve yumuşak doku ile ilgili cerrahi prosedürlerde kullanıldığında, içeriğinde bulunan yoğun sitokin ve büyüme faktörlerinin kontrollü salınımı sağlar. Bu durum doğal yara iyileşme sürecini hızlandırmaktadır. Ayrıca, otojen kaynaklı olduklarından herhangi bir immünolojik reaksiyon ve enfeksiyona yol açmamaları en önemli avantajlarıdır. Tam kan farklı devirlerde ve farklı sürelerde santrifüj edildiğinde içeriği birbirinden farklı olan trombosit kaynaklı ürünler elde edilmiştir. PRP, PRGF, PRF ve CGF gibi ürünlere bakıldığında yeni keşfedilen her ürünün bir öncekine göre daha gelişmiş özellikleri olduğu görülmektedir. Bu derlemenin amacı; PRP, PRGF, PRF ve CGF gibi trombosit konsantrasyonlarının tarihsel gelişimi ve özellikleri hakkında bilgi vermektir.

Anahtar Kelimeler

trombosit konsantreleri,Trombositten zengin plazma,Plazmadan zengin fibrin,Konsantre büyüme faktörü

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Mehmet Kızıltoprak
Türkiye

Mustafa özay Uslu ^*
Türkiye

Publication Date

July 20, 2018

Submission Date

January 19, 2018

Acceptance Date

April 9, 2018

Published in Issue

Year 1970 Volume: 21 Number: 2

DOI

https://doi.org/10.7126/cumudj.381546

IZ

https://izlik.org/JA77HW49CZ

Cite

RIS / Bibtex

EndNote

Kızıltoprak M, Uslu M özay (July 1, 2018) Diş Hekimliğinde Trombosit Konsantrasyonlarinin Tarihsel Gelişimi ve Özellikleri. Cumhuriyet Dental Journal 21 2 152–166.

Cited By

The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites

Cumhuriyet Dental Journal

https://doi.org/10.7126/cumudj.471947

Comparison of growth factor concentrations in platelet-rich fibrin biomaterial in different systemic diseases

Clinical Oral Investigations

https://doi.org/10.1007/s00784-025-06673-y

Historical Development and Properties of Platelet Concentrates in Dentistry

Diş Hekimliğinde Trombosit Konsantrasyonlarinin Tarihsel Gelişimi ve Özellikleri

Öz

Anahtar Kelimeler

Historical Development and Properties of Platelet Concentrates in Dentistry

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites

Comparison of growth factor concentrations in platelet-rich fibrin biomaterial in different systemic diseases