Panoramic Radiomorphometric Indices and Quantitative Heel Ultrasonography in Postmenopausal Diabetic and Non-Diabetic Women: A Comparative Study
Abstract
Objective: To evaluate the impact of diabetes mellitus on bone density measurements using Radiomorphometric parameters on digital panoramic radiographs and quantitative ultrasonographic heel indices for early osteoporosis detection. Materials and Methods: The study included 100 postmenopausal diabetic and non-diabetic women, undergoing panoramic radiographs. Quantitative ultrasonography of the heel was performed to obtain T-scores. Mandibular Cortical Index (MCI), Mental Index (MI), and Panoramic Mandibular Index (PMI) were assessed to quantify mandibular bone mass. Observations were compared between two observers, and interobserver variability was analyzed for reliability. Statistical analysis was performed to evaluate correlations between these indices. Results: Diabetic postmenopausal women showed reduced mandibular bone mass, with a mean MI of less than 3 mm. A C3 cortical pattern was predominantly observed in diabetic patients aged over 60 years, indicating cortical thinning. PMI measurements showed significant positive correlation with T-scores (r = 0.670 and 0.641 for the two observers, respectively; p <0.001). Conclusion: Panoramic parameters such as PMI, MI, and MCI significantly correlate with Heel Index measurements and provide effective tools for early osteoporosis detection in diabetic and non-diabetic postmenopausal women. These indices may serve as useful adjunctive screening tools in dental settings for identifying postmenopausal women at risk of reduced bone mineral density
Keywords
References
- 1. Abdulameer SA, Sulaiman SA, Hassali MA, Subramaniam K, Sahib MN. Osteoporosis and type 2 diabetes mellitus: What do we know, and what can we do? Patient Prefer Adherence 2012;6:435-448.
- 2. Albright F, Reifenstein E. Bone development in diabetic children: A roentgen study. Am J Med Sci 1948;174:313-319.
- 3. Bonjour JP, Chevalley T, Rizzoli R, Ferrari S. Gene-environment interactions in the skeletal response to nutrition and exercise during growth. Med Sport Sci 2007;51:64-80.
- 4. Weaver CM. The role of nutrition in optimizing peak bone mass. Asia Pac J Clin Nutr 2008;17:135-137.
- 5. Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, et al. Interim report and recommendations of the World Health Organization task-force for osteoporosis. Osteoporos Int 1999;10:259-264.
- 6. David AP, Indira AP, Srinivasan I, Kumar MP. Assessment of panoramic radiomorphometric indices of mandible in diabetes mellitus patients and non-diabetic individuals. J Clin Diagn Res 2017;11:ZC35-ZC39.
- 7. Yamagishi S, Nakamura K, Inoue H. Possible participation of advanced glycation end products in the pathogenesis of osteoporosis in diabetic patients. Med Hypotheses 2005;65:1013-1015.
- 8. Alikhani M, Alikhani Z, Boyd C, MacLellan CM, Raptis M, Liu R, et al. Advanced glycation end products stimulate osteoblast apoptosis via the MAP kinase and cytosolic apoptotic pathways. Bone 2007;40:345-353.
Details
Primary Language
English
Subjects
Oral and Maxillofacial Radiology, Public Health Dentistry
Journal Section
Research Article
Authors
Publication Date
July 1, 2026
Submission Date
February 19, 2026
Acceptance Date
May 5, 2026
Published in Issue
Year 2026 Volume: 29 Number: 2