Effect of Fucoidan Incorporation on the Physicochemical Properties of Dental Restorative Materials

Cansu Yıkıcı Çöl; Merve Nezir; Suat Özcan

doi:10.7126/cumudj.1818192

EN TR

Effect of Fucoidan Incorporation on the Physicochemical Properties of Dental Restorative Materials

Abstract

Objectives The aim of this study was to evaluate the wettability, surface and molecular characterization of three different restorative materials (Mineral Trioxide Aggregate [MTA], glass ionomer cement [GIC] and alkasite [AL]) added with fucoidan. Materials and Methods Nine experimental groups were established by incorporating 0%, 2.5%, and 5% fucoidan by weight into the powder phase of MTA, AL, and GIC, followed by mixing according to manufacturers’ instructions. Cylindrical samples (3 mm diameter × 2 mm height ) were molded and stored at 37°C under 100% humidity. Contact Angle Analysis, SEM/EDS, and FTIR spectroscopy evaluations were performed. One-way ANOVA and Tukey post-hoc tests (p < 0.05) were applied for statistical analysis. Results Fucoidan incorporation induced material-specific changes in wettability, chemical composition, and surface morphology. While contact angle values increased in MTA and AL, GIC showed improved wettability at 2.5%. FT-IR analysis confirmed chemical interactions, especially through glycosidic and sulfate bands. SEM-EDS revealed disrupted or reorganized microstructures and altered elemental distributions, including increased fluorine and silicate presence. Conclusions Fucoidan addition improved wettability without compromising the matrix, supporting its potential for advanced restorative materials.

Keywords

Fukoidan İlavesinin Dental Restoratif Malzemelerinin Fizikokimyasal Özelliklerine Etkisi

Öz

Amaç: Bu çalışmanın amacı, fukoidan eklenmiş üç farklı restoratif materyalin (Mineral Trioksit Agregat [MTA], cam iyonomer siman [CİS] ve alkasit [AL]) ıslanabilirlik, yüzey özellikleri ve moleküler karakterizasyonunu değerlendirmektir. Gereç ve Yöntem: MTA, AL ve GIC’in toz fazına ağırlıkça %0, %2.5 ve %5 oranlarında fukoidan ilavesiyle dokuz deney grubu oluşturulmuştur. Karışımlar üretici talimatlarına göre hazırlanmış, silindirik örnekler (3 mm çap × 2 mm yükseklik) kalıplanarak 37°C’de ve %100 nem koşullarında bekletilmiştir. Temas Açısı Analizi, SEM/EDS ve FTIR spektroskopi değerlendirmeleri gerçekleştirilmiştir. İstatistiksel analizde tek yönlü ANOVA ve Tukey çoklu karşılaştırma testleri uygulanmıştır (p < 0.05). Bulgular: Fukoidan ilavesi, materyale özgü değişiklikler oluşturmuştur. MTA ve AL gruplarında temas açısı değerleri artarken, CİS grubunda %2.5 fukoidan ilavesiyle ıslanabilirlik artışı gözlenmiştir. FTIR analizleri, özellikle glikosidik ve sülfat bantları üzerinden kimyasal etkileşimlerin varlığını doğrulamıştır. SEM-EDS incelemeleri, bozulmuş veya yeniden düzenlenmiş mikroyapılar ile flor ve silikat varlığında artış dahil olmak üzere değişen elementel dağılımlar göstermiştir. Sonuç: Fukoidan ilavesi, matriks bütünlüğünü koruyarak ıslanabilirliği artırmış ve ileri düzey restoratif materyallerin geliştirilmesinde potansiyel bir katkı maddesi olarak değerlendirilebileceğini ortaya koymuştur.

Anahtar Kelimeler

Supporting Institution

NA

Ethical Statement

This article does not contain any studies with human participants or animals performed by any of the authors; therefore, ethical approval was not required.

Thanks

NA

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Details

Primary Language

English

Subjects

Restorative Dentistry

Journal Section

Research Article

Authors

Cansu Yıkıcı Çöl ^*
0000-0001-8855-7417
Türkiye

Merve Nezir
0000-0001-8902-5471
Türkiye

Suat Özcan
0000-0001-8782-2899
Türkiye

Publication Date

December 29, 2025

Submission Date

November 5, 2025

Acceptance Date

November 24, 2025

Published in Issue

Year 2025 Volume: 28 Number: 4

DOI

https://doi.org/10.7126/cumudj.1818192

IZ

https://izlik.org/JA53PY46YW

Cite

RIS / Bibtex

EndNote

Yıkıcı Çöl C, Nezir M, Özcan S (December 1, 2025) Effect of Fucoidan Incorporation on the Physicochemical Properties of Dental Restorative Materials. Cumhuriyet Dental Journal 28 4 600–607.