Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth

Feyza Ozdemır Kısacık; Ayşe Diljin Keçeci; Nejdet Adanir

doi:10.7126/cumudj.1812243

EN TR

Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth

Abstract

Objectives: This study aimed to evaluate the pulpal effects of 35% hydrogen peroxide used in-office to bleach teeth with dental fluorosis, both in vivo and in vitro. In vivo, histological and clinical effects were assessed. Materials and methods: Ten fluorosed teeth were used for histopathological comparison of two bleaching agents. Additionally, 96 fluorosed maxillary anterior teeth (TFI 3–7) from 17 patients (ages 18–38) were evaluated for bleaching effectiveness and side effects including hypersensitivity, vitality loss, and radiographic changes. In vitro, 90 extracted fluorosed teeth were analyzed for hydrogen peroxide penetration. Data were analyzed using Kruskal-Wallis, ANOVA, and repeated measures ANOVA. Results: Findings showed no irreversible pulpal damage or periradicular abnormalities. Maximum penetration was 16.2 mM for Whiteness HP Maxx and 18.3 mM for Opalescence Xtra. Penetration correlated with fluorosis severity but remained below levels affecting pulpal enzymes. Coclusions: Both bleaching agents were effective and safe for treating mild to severe fluorosis without affecting pulp or periodontium.

Keywords

Florozisli Dişlerde Kullanılan İki Ofis Tipi Beyazlatma Materyalinin Pulpa Üzerine Etkileri

Abstract

Amaç: Bu çalışmanın amacı, dental florozisli dişlerin ofis tipi beyazlatmada kullanılan %35 hidrojen peroksitin pulpa üzerindeki etkilerini hem in vivo hem de in vitro koşullarda değerlendirmektir. Gereç ve Yöntemler: İn vivo olarak histolojik ve klinik etkiler incelenmiştir. İki farklı beyazlatma ajanının histopatolojik karşılaştırması için 10 florozisli diş kullanılmıştır. Ayrıca 17 hastadan (18–38 yaş) elde edilen 96 florozisli üst çene anterior dişi (TFI 3–7), beyazlatma etkinliği ve hipersensitivite, vitalite kaybı ve radyografik değişiklikler gibi yan etkiler açısından değerlendirilmiştir. İn vitro olarak ise, 90 adet çekilmiş florozisli dişte hidrojen peroksit penetrasyonu analiz edilmiştir. Veriler Kruskal-Wallis, ANOVA ve tekrarlayan ölçümler ANOVA testleri ile değerlendirilmiştir. Bulgular: Bulgular, geri dönüşsüz pulpal hasar veya periradiküler anormallik olmadığını göstermiştir. Maksimum hidrojen peroksit penetrasyonu Whiteness HP Maxx için 16,2 mM, Opalescence Xtra için 18,3 mM olarak bulunmuştur. Penetrasyon florozis şiddeti ile korele olmakla birlikte, pulpal enzimleri etkileyebilecek düzeylerin altında kalmıştır. Sonuçlar: Her iki beyazlatma ajanı da hafif ve şiddetli florozis vakalarının tedavisinde etkili ve güvenli bulunmuş olup, pulpa veya periodontal dokular üzerinde olumsuz etki göstermemiştir.

Keywords

References

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Details

Primary Language

English

Subjects

Endodontics

Journal Section

Research Article

Authors

Feyza Ozdemır Kısacık ^*
0000-0001-5229-9575
Türkiye

Ayşe Diljin Keçeci
0000-0003-4758-6521
Türkiye

Nejdet Adanir
0000-0002-6235-3448
Indonesia

Publication Date

July 1, 2026

Submission Date

October 28, 2025

Acceptance Date

January 11, 2026

Published in Issue

Year 2026 Volume: 29 Number: 2

DOI

https://doi.org/10.7126/cumudj.1812243

IZ

https://izlik.org/JA37BA67XK

Cite

RIS / Bibtex

APA

Ozdemır Kısacık, F., Keçeci, A. D., & Adanir, N. (2026). Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth. Cumhuriyet Dental Journal, 29(2), 270-279. https://doi.org/10.7126/cumudj.1812243

AMA

1.Ozdemır Kısacık F, Keçeci AD, Adanir N. Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth. Cumhuriyet Dent J. 2026;29(2):270-279. doi:10.7126/cumudj.1812243

Chicago

Ozdemır Kısacık, Feyza, Ayşe Diljin Keçeci, and Nejdet Adanir. 2026. “Pulpal Effects of the Two Office Bleaching Materials on Fluorosed Teeth”. Cumhuriyet Dental Journal 29 (2): 270-79. https://doi.org/10.7126/cumudj.1812243.

EndNote

Ozdemır Kısacık F, Keçeci AD, Adanir N (July 1, 2026) Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth. Cumhuriyet Dental Journal 29 2 270–279.

IEEE

[1]F. Ozdemır Kısacık, A. D. Keçeci, and N. Adanir, “Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth”, Cumhuriyet Dent J, vol. 29, no. 2, pp. 270–279, July 2026, doi: 10.7126/cumudj.1812243.

ISNAD

Ozdemır Kısacık, Feyza - Keçeci, Ayşe Diljin - Adanir, Nejdet. “Pulpal Effects of the Two Office Bleaching Materials on Fluorosed Teeth”. Cumhuriyet Dental Journal 29/2 (July 1, 2026): 270-279. https://doi.org/10.7126/cumudj.1812243.

JAMA

1.Ozdemır Kısacık F, Keçeci AD, Adanir N. Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth. Cumhuriyet Dent J. 2026;29:270–279.

MLA

Ozdemır Kısacık, Feyza, et al. “Pulpal Effects of the Two Office Bleaching Materials on Fluorosed Teeth”. Cumhuriyet Dental Journal, vol. 29, no. 2, July 2026, pp. 270-9, doi:10.7126/cumudj.1812243.

Vancouver

1.Feyza Ozdemır Kısacık, Ayşe Diljin Keçeci, Nejdet Adanir. Pulpal Effects of the Two Office bleaching Materials on Fluorosed Teeth. Cumhuriyet Dent J. 2026 Jul. 1;29(2):270-9. doi:10.7126/cumudj.1812243