Influence of Surface Properties on Candida albicans Adhesion to Denture Base Materials Fabricated by Different Techniques

Onur Topaloğlu; Ayhan Gürbüz; Sema Murat

doi:10.7126/cumudj.1744874

EN

Influence of Surface Properties on Candida albicans Adhesion to Denture Base Materials Fabricated by Different Techniques

Abstract

Purpose: This in vitro study aimed to evaluate and compare the surface roughness, wettability (contact angle), and Candida albicans (C. albicans) adhesion of denture base materials fabricated using different techniques. Materials and Methods: Six materials were tested: conventional PMMA, CAD-CAM PMMA, PEEK, polyamide, titanium, and cobalt-chromium. Surface roughness (Ra) and contact angle (°) were measured, and Candida albicans adhesion was assessed by counting colony-forming units (CFU/mL). Data were analyzed using Kruskal–Wallis and Mann–Whitney U tests with Bonferroni correction. Spearman’s correlation was used to evaluate the relationship between surface properties and fungal adhesion. Results: Significant differences were found among the materials in surface roughness, contact angle, and Candida adhesion (p < 0.0001). Conventional PMMA, polyamide, and PEEK showed the highest surface roughness, whereas Co-Cr and titanium exhibited the smoothest surfaces. Contact angle measurements indicated that Co-Cr was the most hydrophobic, while titanium was the most hydrophilic. The highest Candida adhesion was observed on polyamide and PEEK, and the lowest on Co-Cr. Positive correlation was found between surface roughness and fungal adhesion (ρ = 0.625), while a negative correlation was found between contact angle and adhesion (ρ = –0.533). Conclusion: Both surface roughness and wettability significantly influence C. albicans adhesion. Materials with smoother and more hydrophilic surfaces, such as CAD-CAM PMMA and titanium, demonstrated reduced fungal colonization, highlighting the importance of material selection in preventing prosthesis-related infections.

Keywords

References

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Details

Primary Language

English

Subjects

Prosthodontics

Journal Section

Research Article

Authors

Onur Topaloğlu ^*
0000-0002-4261-4815
Türkiye

Ayhan Gürbüz
0000-0003-4066-9609
Türkiye

Sema Murat
0000-0003-0632-5095
Türkiye

Publication Date

September 30, 2025

Submission Date

July 18, 2025

Acceptance Date

September 3, 2025

Published in Issue

Year 2025 Volume: 28 Number: 3

DOI

https://doi.org/10.7126/cumudj.1744874

IZ

https://izlik.org/JA78WY23MK

Cite

RIS / Bibtex

EndNote

Topaloğlu O, Gürbüz A, Murat S (September 1, 2025) Influence of Surface Properties on Candida albicans Adhesion to Denture Base Materials Fabricated by Different Techniques. Cumhuriyet Dental Journal 28 3 427–434.

Cited By

Enhanced Mechanical and Surface Performance of Three-Dimensionally Printed Denture Base Resin via Zinc Oxide and Samarium Oxide Nanoparticle Reinforcement

Materials

https://doi.org/10.3390/ma19050830

Emergent Candida Species on Healthcare Surfaces: Abiotic Reservoirs as a Source of Invasive Candidiasis

Microorganisms

https://doi.org/10.3390/microorganisms14020367

Influence of Surface Properties on Candida albicans Adhesion to Denture Base Materials Fabricated by Different Techniques

Abstract

Keywords

Öz

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

Enhanced Mechanical and Surface Performance of Three-Dimensionally Printed Denture Base Resin via Zinc Oxide and Samarium Oxide Nanoparticle Reinforcement

Emergent Candida Species on Healthcare Surfaces: Abiotic Reservoirs as a Source of Invasive Candidiasis