Research Article
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Effects of intracanal medicaments on the bond strength of calcium silicate-based cements in regenerative endodontic treatment: an in vitro study

Year 2025, Volume: 28 Issue: 4, 533 - 544, 29.12.2025

Mutlunur Önder Peker , Leyla Ayranci

https://doi.org/10.7126/cumudj.1719193

Abstract

Objectives: The physical and chemical properties of calcium silicate-based cements can be influenced by a number of factors. The aim of this study was to investigate the effect of various irrigation methods and placed with different techniques calcium silicate based cements on dentin bonding strength after two different intracanal medications. Materials and Methods: The simulated immature teeth were randomly divided into five groups according to the intracanal medicaments and medicaments removal techniques to be used. Group 1: Calcium Hydroxide (Ca(OH)2) + removal with ethylenediaminetetraacetic acid (EDTA) (conventional neddle irrigation) , Group 2: Ca(OH)2 + removal with EDTA + Passive ultrasonic irrigation (PUI), Group 3: Double antibiotic paste (DAP) consisting of metronidazole and ciprofloxacin + removal with EDTA (conventional neddle irrigation), Group 4: DAP+ removal with EDTA + PUI, Group 5: Control (n = 20 teeth for each group). Parallel transverse sections were obtained in the coronal to the apical direction (4 slices per tooth). Then, specimens were divided into four subgroups according to the calcium silicate-based cements and placement techniques to be applied. A push-out test was used to measure bond strength. Data were analyzed using four-way ANOVA and Tukey’s multiple comparison test. Results: As a result of the variance analysis, the interactions between the factors were not statistically significant (p> 0.05), whereas the main effects of all factors were statistically significant. Conclusions: In regenerative treatment procedures, intracanal medicament type, irrigation methods, endodontic cement type and placement technique to be used affected the bond strength

Keywords

biodentine bond strength MTA regenerative endodontic treatment

Project Number

Ordu university project B-1816

Thanks

Ordu university project B-1816. Many thanks to Ordu University for supporting our research

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There are 57 citations in total.

Details

Primary Language English
Subjects Endodontics, Dental Materials
Journal Section Research Article
Authors

Mutlunur Önder Peker 0000-0002-7089-3049

Leyla Ayranci 0000-0001-6410-865X

Project Number Ordu university project B-1816
Submission Date June 13, 2025
Acceptance Date August 4, 2025
Publication Date December 29, 2025
Published in Issue Year 2025 Volume: 28 Issue: 4

Cite

EndNote Önder Peker M, Ayranci L (December 1, 2025) Effects of intracanal medicaments on the bond strength of calcium silicate-based cements in regenerative endodontic treatment: an in vitro study. Cumhuriyet Dental Journal 28 4 533–544.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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