Effects of intracanal medicaments on the bond strength of calcium silicate-based cements in regenerative endodontic treatment: an in vitro study

Mutlunur Önder Peker; Leyla Ayranci

doi:10.7126/cumudj.1719193

Effects of intracanal medicaments on the bond strength of calcium silicate-based cements in regenerative endodontic treatment: an in vitro study

Abstract

Objectives: The physical and chemical properties of calcium silicate-based cements can be influenced by a number of factors. The aim of this study was to investigate the effect of various irrigation methods and placed with different techniques calcium silicate based cements on dentin bonding strength after two different intracanal medications. Materials and Methods: The simulated immature teeth were randomly divided into five groups according to the intracanal medicaments and medicaments removal techniques to be used. Group 1: Calcium Hydroxide (Ca(OH)2) + removal with ethylenediaminetetraacetic acid (EDTA) (conventional neddle irrigation) , Group 2: Ca(OH)2 + removal with EDTA + Passive ultrasonic irrigation (PUI), Group 3: Double antibiotic paste (DAP) consisting of metronidazole and ciprofloxacin + removal with EDTA (conventional neddle irrigation), Group 4: DAP+ removal with EDTA + PUI, Group 5: Control (n = 20 teeth for each group). Parallel transverse sections were obtained in the coronal to the apical direction (4 slices per tooth). Then, specimens were divided into four subgroups according to the calcium silicate-based cements and placement techniques to be applied. A push-out test was used to measure bond strength. Data were analyzed using four-way ANOVA and Tukey’s multiple comparison test. Results: As a result of the variance analysis, the interactions between the factors were not statistically significant (p> 0.05), whereas the main effects of all factors were statistically significant. Conclusions: In regenerative treatment procedures, intracanal medicament type, irrigation methods, endodontic cement type and placement technique to be used affected the bond strength

Keywords

Project Number

Ordu university project B-1816

Thanks

Ordu university project B-1816. Many thanks to Ordu University for supporting our research

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Details

Primary Language

English

Subjects

Endodontics , Dental Materials

Journal Section

Research Article

Authors

Mutlunur Önder Peker
0000-0002-7089-3049
Türkiye

Leyla Ayranci ^*
0000-0001-6410-865X
Türkiye

Publication Date

December 29, 2025

Submission Date

June 13, 2025

Acceptance Date

August 4, 2025

Published in Issue

Year 2025 Volume: 28 Number: 4

DOI

https://doi.org/10.7126/cumudj.1719193

IZ

https://izlik.org/JA48WY57YT

Cite

RIS / Bibtex

EndNote

Önder Peker M, Ayranci L (December 1, 2025) Effects of intracanal medicaments on the bond strength of calcium silicate-based cements in regenerative endodontic treatment: an in vitro study. Cumhuriyet Dental Journal 28 4 533–544.