Research Article

Detection of Periapical Lesions on Panoramic Radiographs Using Artificial Intelligence

Volume: 28 Number: 4 December 29, 2025
TR EN

Detection of Periapical Lesions on Panoramic Radiographs Using Artificial Intelligence

Abstract

Objective: This study aimed to compare the performance of two deep learning models, YOLOv8 and Cascade Mask R-CNN, for the artificial intelligence-assisted automatic detection of periapical lesions in dental panoramic radiographs. Material and Methods: A total of 1861 panoramic radiographs were reviewed, and 602 images containing periapical lesions were included in the study. In these radiographs, a total of 1059 lesions were identified. Observer agreement for lesion detection was evaluated using Kappa analysis. The included radiographs were divided into three datasets: training (70%), validation (20%), and testing (10%). The YOLOv8 and Cascade Mask R-CNN models were trained using the PyTorch library. The trained models were then applied to the test dataset, and true positive, false positive, true negative, and false negative outcomes were recorded for periapical lesion detection. Based on these outcomes, accuracy, sensitivity, specificity, precision, and F1 score were calculated for each model. Results: On the test dataset, the YOLOv8 model achieved 96.9% accuracy, 53.5% sensitivity, 90% precision, and an F1 score of 0.671, whereas the Cascade Mask R-CNN model achieved 97.6% accuracy, 76.2% sensitivity, 81.9% precision, and an F1 score of 0.790. Although YOLOv8 produced fewer false positives, it failed to detect a considerable number of lesions. In contrast, Cascade Mask R-CNN was able to detect more lesions but generated relatively more false positives. Conclusion: Artificial intelligence models demonstrated potential as supportive tools in clinical decision support systems based on their accuracy rates. However, the current sensitivity levels were insufficient to reliably undertake diagnostic responsibilities alone, suggesting that these models should not yet be used independently for clinical decision-making.

Keywords

Supporting Institution

This study was supported by the KOSGEB (Approval no: 7AHNN).

Ethical Statement

This study was conducted with the approval of the Ethics Committee of Karamanoğlu Mehmetbey University Faculty of Medicine (Approval No: 09-2024/01)

References

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Details

Primary Language

English

Subjects

Oral and Maxillofacial Radiology , Endodontics

Journal Section

Research Article

Publication Date

December 29, 2025

Submission Date

May 28, 2025

Acceptance Date

July 11, 2025

Published in Issue

Year 2025 Volume: 28 Number: 4

EndNote
Kölüş T, Akbulut MB, Güleç M (December 1, 2025) Detection of Periapical Lesions on Panoramic Radiographs Using Artificial Intelligence. Cumhuriyet Dental Journal 28 4 520–525.

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


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