Research Article

ASSESSMENT OF DMFT INDEXES, SALIVARY FLOW RATE, PH, AND DETECTIONS OF S.MUTANS SALIVARY LEVELS BY A QUANTITATIVE REAL-TIME PCR IN POLYCYSTIC OVARY SYNDROME

Volume: 25 Number: 2 June 30, 2022
EN

ASSESSMENT OF DMFT INDEXES, SALIVARY FLOW RATE, PH, AND DETECTIONS OF S.MUTANS SALIVARY LEVELS BY A QUANTITATIVE REAL-TIME PCR IN POLYCYSTIC OVARY SYNDROME

Abstract

Objectives: PCOS is an endocrine disorder that is common in women. However, PCOS effects on oral and dental health have not been stated clearly. The aim of this study is to examine the effects of Polycystic Ovary Syndrome (PCOS), which is common in women of reproductive age, on saliva and dental tissues in these women. Materials and Methods: One-hundred individuals who were / were not diagnosed with PCOS and insulin resistance were included in this study (n=100). Subsequently, individuals, with PCOS and insulin resistance (PCOSID +), with PCOS and non-insulin resistance (PCOSID-), without PCOS and insulin resistance (ControlID +) and without PCOS and non-insulin resistance (ControlID-) were divided into 4 groups (n=25). DMFT (Decayed, Missing, Filled Teeth) index was used for dental health evaluation, while pH meter was used for saliva pH measurement. Also, Streptococcus Mutans (S. Mutans) numbers were analyzed by the real-time Polymerase Chain Reaction (PCR) method. In statistical analysis p<0.05 was considered significant. Results: In comparison among the groups, significant differences were found in terms of DMFT index, S. Mutans, and salivary pH values (p<0.05). Among the compared groups, the highest DMFT index, S. Mutans values were found in the PCOSID(+) group, the lowest in ControlID(-) group, while the lowest saliva pH value was found in the PCOSID(+) group. Conclusions: S. Mutans and DMFT index values were found highly in the saliva of PCOS patients, which is a multifactorial syndrome, and it is determined that salivary parameters have an effect on this situation.

Keywords

Supporting Institution

Gaziantep Universitesi Bilimsel Araştırmalar Projeler Birimi

Project Number

DHF.UT.19.04.

References

  1. 1. Barber TM, Franks S. Obesity and polycystic ovary syndrome. Clin. Endocrinol. 2021;95(4):531-541.
  2. 2. Norman RJ, Dewailly D, Legro RS, Hickey TE. Polycystic ovary syndrome. The Lancet. 2007;370(9588):685-697.
  3. 3. Indhavivadhana S, Kuichanuan M, Wongwananuruk T, Techatraisak K, Chantrapanichkul P, Dangrat C. Correlation of Hyperandrogenemia and Metabolic Syndrome in Thai Women With Polycystic Ovary Syndrome (PCOS). 2021; 1-12.
  4. 4. Fulghesu AM, Piras C, Dessì A, et al. Urinary Metabolites Reveal Hyperinsulinemia and Insulin Resistance in Polycystic Ovarian Syndrome (PCOS). Metabolites. 2021;11(7):437.
  5. 5. Dursun E, Akalın FA, Güncü GN, et al. Periodontal disease in polycystic ovary syndrome. Fertil. Steril. 2011;95(1):320-323.
  6. 6. Kassebaum N, Bernabé E, Dahiya M, Bhandari B, Murray C, Marcenes W. Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. J. Dent. Res. 2014;93(11):1045-1053.
  7. 7. Cardoso EM, Reis C, Manzanares-Céspedes MC. Chronic periodontitis, inflammatory cytokines, and interrelationship with other chronic diseases. Postgrad Med. 2018;130(1):98-104.
  8. 8. Bowen W, Koo H. Biology of Streptococcus mutans-derived glucosyltransferases: role in extracellular matrix formation of cariogenic biofilms. Caries Res. 2011;45(1):69-86.

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Publication Date

June 30, 2022

Submission Date

June 17, 2022

Acceptance Date

June 21, 2022

Published in Issue

Year 2022 Volume: 25 Number: 2

EndNote
Yeniçeri Hilaloğlu NE, Gursel Surmelioglu D (June 1, 2022) ASSESSMENT OF DMFT INDEXES, SALIVARY FLOW RATE, PH, AND DETECTIONS OF S.MUTANS SALIVARY LEVELS BY A QUANTITATIVE REAL-TIME PCR IN POLYCYSTIC OVARY SYNDROME. Cumhuriyet Dental Journal 25 2 163–171.

Cited By

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


CDJ accepts articles in English. Submitting a paper to CDJ is free of charges. In addition, CDJ has not have article processing charges.

Frequency: Four times a year (March, June, September, and December)

IMPORTANT NOTICE

All users of Cumhuriyet Dental Journal should visit to their user's home page through the "https://dergipark.org.tr/tr/user" " or "https://dergipark.org.tr/en/user" links to update their incomplete information shown in blue or yellow warnings and update their e-mail addresses and information to the DergiPark system. Otherwise, the e-mails from the journal will not be seen or fall into the SPAM folder. Please fill in all missing part in the relevant field.

Please visit journal's AUTHOR GUIDELINE to see revised policy and submission rules to be held since 2020.