Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics

Kalyanam Rashmi Durga; Ravındra S; Prakash M Halami

doi:10.7126/cumudj.1094906

EN

Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics

Abstract

INTRODUCTION; The treatment of Periodontal disease in Diabetic subjects should also focus on lowering blood glucose levels, which might act as an adjuvant to conventional Periodontal treatment. In the form of Probiotics, Bacterial therapy offers a dual role in controlling blood glycemic levels and reducing colonization of oral bacteria. This study aimed to evaluate the efficacy of probiotics in managing Periodontitis among Diabetic and Non-Diabetic subjects. METHODOLOGY; This study was designed as a randomized, double-blinded clinical trial among Diabetic and Non-diabetic subjects with Periodontitis. Twenty-four subjects in each Diabetic and non-diabetic group were randomly assigned into two probiotic test sub-groups and one placebo sub-group. Lactobacillus fermentum MCC2760 and Bifidobacterium longum NCIM5684 probiotic chewing gums were provided to subjects in test groups to use twice a day for 30 days. Supragingival plaque samples were collected at baseline and 30 days to analyze total bacterial count and subgingival plaque for P.gingivalis, A.actinomycetemcomitans through qPCR. Clinical parameters were recorded at baseline, 30, 45, and 90 days. RESULTS; After 30 days, a significant reduction in PI, GI, PPD, and Gingival bleeding Index was observed in SRP and SRP+Probiotic groups. There is a significant reduction in total bacterial count among probiotic groups compared to placebo. PCR analysis revealed non-significant reduction of p.gingivalis and A.actinomycetemcomitans in test groups. Intergroup comparison between Diabetic and Non-diabetic groups did not show any significant differences either in clinical or microbial parameters. CONCLUSION; Probiotic functional foods can be delivered as an adjunct to SRP to manage Periodontitis in systemically compromised subjects. Long-time use of probiotics is recommended to maintain the recolonization of bacteria in periodontal tissues.

Keywords

Supporting Institution

JSS Dental College

Project Number

03

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Kalyanam Rashmi Durga ^*
0000-0002-7946-3002
India

Ravındra S
0000-0002-5511-9098
India

Prakash M Halami
0000-0002-0293-1891
India

Publication Date

September 29, 2023

Submission Date

April 3, 2022

Acceptance Date

July 2, 2023

Published in Issue

Year 2023 Volume: 26 Number: 3

DOI

https://doi.org/10.7126/cumudj.1094906

IZ

https://izlik.org/JA96MP88KE

Cite

RIS / Bibtex

APA

Rashmi Durga, K., S, R., & Halami, P. M. (2023). Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics. Cumhuriyet Dental Journal, 26(3), 220-226. https://doi.org/10.7126/cumudj.1094906

AMA

1.Rashmi Durga K, S R, Halami PM. Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics. Cumhuriyet Dent J. 2023;26(3):220-226. doi:10.7126/cumudj.1094906

Chicago

Rashmi Durga, Kalyanam, Ravındra S, and Prakash M Halami. 2023. “Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics”. Cumhuriyet Dental Journal 26 (3): 220-26. https://doi.org/10.7126/cumudj.1094906.

EndNote

Rashmi Durga K, S R, Halami PM (September 1, 2023) Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics. Cumhuriyet Dental Journal 26 3 220–226.

IEEE

[1]K. Rashmi Durga, R. S, and P. M. Halami, “Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics”, Cumhuriyet Dent J, vol. 26, no. 3, pp. 220–226, Sept. 2023, doi: 10.7126/cumudj.1094906.

ISNAD

Rashmi Durga, Kalyanam - S, Ravındra - Halami, Prakash M. “Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics”. Cumhuriyet Dental Journal 26/3 (September 1, 2023): 220-226. https://doi.org/10.7126/cumudj.1094906.

JAMA

1.Rashmi Durga K, S R, Halami PM. Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics. Cumhuriyet Dent J. 2023;26:220–226.

MLA

Rashmi Durga, Kalyanam, et al. “Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics”. Cumhuriyet Dental Journal, vol. 26, no. 3, Sept. 2023, pp. 220-6, doi:10.7126/cumudj.1094906.

Vancouver

1.Kalyanam Rashmi Durga, Ravındra S, Prakash M Halami. Probiotic Chewing Gums for Adjuctive Treatment of Periodontitis in Diabetics. Cumhuriyet Dent J. 2023 Sep. 1;26(3):220-6. doi:10.7126/cumudj.1094906

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