Araştırma Makalesi
BibTex RIS Kaynak Göster

Tıp Doktorlarının İlaçlara Bağlı Diş Eti Büyümesi Hakkında Farkındalıklarının Değerlendirilmesi: Bir Ön Çalışma

Yıl 2024, Cilt: 19 Sayı: 1, 128 - 133, 28.03.2024
https://doi.org/10.17517/ksutfd.1396757

Öz

Amaç: Dişeti büyümesi, etyolojisinde dental plak kaynaklı inflamasyon, hormonlar, genetik, malign veya benign lezyonlar, ilaçlar olan hiperplazi ve hipertrofi ile karakterize klinik durumdur. Antikonvülsanlar, kalsiyum kanal blokerleri, immünsüpresanlar ve yüksek doz oral kontraseptifler dişeti büyümesi yapan ilaçlardır. Çalışmamızın amacı; uzman ve pratisyen tıp doktorları arasında dişeti büyümesi yapan ilaç farkındalığını araştırmaktır.
Gereç ve Yöntemler: Anket çalışmamıza toplamda 100 kişi katıldı. Katılımcıların dişeti büyümesi yapan ilaç farkındalığının değerlendirmek için self-reported bir anket formu oluşturuldu. Anket formu Google forms üzerinden online olacak şekilde hazırlandı. Anket çevrimiçi olduğundan, anketin dağıtılması ve tanıtılması yöntemi sosyal ağ üzerinden (facebook) ve Apple store’dan (WhatsApp) yapıldı.
Bulgular: Katılımcıların % 27si antikonvulzanların dişeti büyümesi yaptığını bildirmiştir, bunu % 23 oranında immunsüpresanlar, % 19 ile Ca canal blokerleri, % 11 ile oral kontraseptifler takip etmiştir. Literatürde antibiyotikler ve Non-Steridal Antiinflamatuar (NSAİ) ilaçların dişeti büyümesi yaptığına dair bir konsensus olmamasıyla birlikte, katılımcıların %9,2si antibiyotiklerin %4,3 ü NSAİ’lerin, %5,4 ü antideprasanların dişeti büyümesi yaptığını bildirmişlerdir.
Sonuç: Sağlık çalışanları arasında yapılan ters ilaç etkisi farkındalığını değerlendiren çalışmalarda, çalışanların bu konuda bilgi sahibi olduğu ama bu durumu bildirmede yetersiz kaldığını göstermiştir. Bizim çalışmamızda, pratisyen ve uzman tıp hekimlerin dişeti büyümesi yapan ilaç farkındalığının yetersiz olduğunu düşünmekteyiz.

Proje Numarası

yok

Kaynakça

  • Beaumont J, Chesterman J, Kellett M, Durey K. Gingival overgrowth: Part 1: aetiology and clinical diagnosis. British dental journal.2017; 222(2): 85-91.
  • Murakami S, Mealey BL, Mariotti A, Chapple ILC. Dental plaque-induced gingival conditions [Internet]. Journal of periodontology. 2018;89:17–27.
  • Angelopoulos AP, Goaz PW. Incidence of diphenylhydantoin gingival hyperplasia. Oral Surgery, Oral Med Oral Pathol. 1972;34:898–906.
  • Ellis JS, Seymour RA, Steele JG, Robertson P, Butler TJ, Thomason JM. Prevalence of Gingival Overgrowth Induced by Calcium Channel Blockers: A Community-Based Study. J Periodontol. 1999;70:63–67.
  • Hassell TM, Hefti AF. Drug-Induced Gingival Overgrowth: Old Problem, New Problem. Vol. 2, Critical Reviews in Oral Biology and Medicine. 1991;103-137.
  • T Al-Saffar M. The Effects of Contraceptive Pills on Oral Health: A Review Study. Acta Sci Dent Scienecs . 2019;3:61–64.
  • Seymour RA, Ellis JS, Thomason JM. Risk factors for drug-induced gingival overgrowth. J Clin Periodontol 2000;27:217–23.
  • Chesterman J, Beaumont J, Kellett M, Durey K. Gingival overgrowth: Part 2: management strategies. Nat Publ Gr 2017;159-65.
  • Pavlic V, Zubovic N, Ilic S, Adamovic T. Untypical Amlodipine-Induced Gingival Hyperplasia. Case Reports in Dentistry 2015;1-4
  • Prakah R, Mohan S, Rastogi K, Bhushan R, Verma S. Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy. Case Reports. 2013; bcr2013008679.
  • Seid MA, Asmamaw •, Kasahun E, Bamlak •, Mante M, Saron •, et al. Healthcare professionals’ knowledge, attitude and practice towards adverse drug reaction (ADR) reporting at the health center level in Ethiopia. Int J Clin Pharm. 2018;40: 895–902.
  • Le Msc TT, Thanh T, Nguyen H, Nguyen C, Ha N, Msc T, et al. Factors associated with spontaneous adverse drug reaction reporting among healthcare professionals in Vietnam. J Clin Pharm Ther [Internet] 2020;45:122–27.
  • Lin, H., Zhang, H., Yan, Y., Liu, D., Zhang, R., Liu, Y. et al. Knowledge, awareness, and behaviors of endocrinologists and dentists for the relationship between diabetes and periodontitis. Diabetes Res Clin Pract 2014;106:428–34.
  • Dubar, M., Delatre, V., Moutier, C., Sy, K., & Agossa, K. Awareness and practices of general practitioners towards the oral-systemic disease relationship: A regionwide survey in France. J Eval Clin Pract 2020;26:1722–30.
  • Taşdemir Z, Alkan BA rz. Knowledge of medical doctors in Turkey about the relationship between periodontal disease and systemic health. Braz Oral Res 2015; 29:55.
  • Rocha, J. M. D., Chaves, V. R., Urbanetz, A. A., Baldissera, R. D. S., & Rösing, C. K.. Obstetricians’ knowledge of periodontal disease as a potential risk factor for preterm delivery and low birth weight. Braz Oral Res 2011;25:248–54.

Evaluation of The Awareness of Medical Practitioners About Drug-Induced Gingival Enlargement: A Preliminary Study

Yıl 2024, Cilt: 19 Sayı: 1, 128 - 133, 28.03.2024
https://doi.org/10.17517/ksutfd.1396757

Öz

Objective: Gingival enlargement is a clinical condition characterized by hyperplasia and hypertrophy, which has an etiology of inflammation originating from dental plaque, hormones, genetics, malignant or benign lesions, and drugs. The drugs causing gingival enlargement include anti-convulsants, calcium channel blockers, immunosuppressants, and high-dose oral contraceptives. This study aimed to investigate the awareness of specialist and practitioner medical doctors about the drugs causing gingival enlargement.
Material and Methods: A total of 100 respondents participated in this questionnaire study. A self-reported questionnaire was formed to evaluate the awareness of the study participants about drugs causing gingival enlargement. The questionnaire was prepared online using Google forms and was introduced and distributed on the social networks of Facebook and WhatsApp.
Results: % 27 of the respondents reported that anti-convulsants caused gingival enlargement, followed by immunosuppressants at the rate of 23%, calcium channel blockers at 19%, and oral contraceptives at 11%. Although there is no consensus in the literature that antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) cause gingival enlargement, 9.2% of the study respondents reported that antibiotics caused gingival enlargement, 4.3% NSAIDs, and 5.4% antidepressants.
Conclusion: In studies evaluating the awareness of healthcare personnel about drug adverse effects, it has been shown that personnel have knowledge on this subject, but do not report this at a sufficient level. The results of this study suggest that specialist and practitioner medical doctors had insufficient awareness about drugs causing gingival enlargement.

Etik Beyan

Approval for this study, which was conducted between March 2021 and October 2021, was granted by the Non-Interventional Clinical Research Ethics Committee (decision no:01, session no:2021/06).

Destekleyen Kurum

Destek alınmamıştır.

Proje Numarası

yok

Kaynakça

  • Beaumont J, Chesterman J, Kellett M, Durey K. Gingival overgrowth: Part 1: aetiology and clinical diagnosis. British dental journal.2017; 222(2): 85-91.
  • Murakami S, Mealey BL, Mariotti A, Chapple ILC. Dental plaque-induced gingival conditions [Internet]. Journal of periodontology. 2018;89:17–27.
  • Angelopoulos AP, Goaz PW. Incidence of diphenylhydantoin gingival hyperplasia. Oral Surgery, Oral Med Oral Pathol. 1972;34:898–906.
  • Ellis JS, Seymour RA, Steele JG, Robertson P, Butler TJ, Thomason JM. Prevalence of Gingival Overgrowth Induced by Calcium Channel Blockers: A Community-Based Study. J Periodontol. 1999;70:63–67.
  • Hassell TM, Hefti AF. Drug-Induced Gingival Overgrowth: Old Problem, New Problem. Vol. 2, Critical Reviews in Oral Biology and Medicine. 1991;103-137.
  • T Al-Saffar M. The Effects of Contraceptive Pills on Oral Health: A Review Study. Acta Sci Dent Scienecs . 2019;3:61–64.
  • Seymour RA, Ellis JS, Thomason JM. Risk factors for drug-induced gingival overgrowth. J Clin Periodontol 2000;27:217–23.
  • Chesterman J, Beaumont J, Kellett M, Durey K. Gingival overgrowth: Part 2: management strategies. Nat Publ Gr 2017;159-65.
  • Pavlic V, Zubovic N, Ilic S, Adamovic T. Untypical Amlodipine-Induced Gingival Hyperplasia. Case Reports in Dentistry 2015;1-4
  • Prakah R, Mohan S, Rastogi K, Bhushan R, Verma S. Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy. Case Reports. 2013; bcr2013008679.
  • Seid MA, Asmamaw •, Kasahun E, Bamlak •, Mante M, Saron •, et al. Healthcare professionals’ knowledge, attitude and practice towards adverse drug reaction (ADR) reporting at the health center level in Ethiopia. Int J Clin Pharm. 2018;40: 895–902.
  • Le Msc TT, Thanh T, Nguyen H, Nguyen C, Ha N, Msc T, et al. Factors associated with spontaneous adverse drug reaction reporting among healthcare professionals in Vietnam. J Clin Pharm Ther [Internet] 2020;45:122–27.
  • Lin, H., Zhang, H., Yan, Y., Liu, D., Zhang, R., Liu, Y. et al. Knowledge, awareness, and behaviors of endocrinologists and dentists for the relationship between diabetes and periodontitis. Diabetes Res Clin Pract 2014;106:428–34.
  • Dubar, M., Delatre, V., Moutier, C., Sy, K., & Agossa, K. Awareness and practices of general practitioners towards the oral-systemic disease relationship: A regionwide survey in France. J Eval Clin Pract 2020;26:1722–30.
  • Taşdemir Z, Alkan BA rz. Knowledge of medical doctors in Turkey about the relationship between periodontal disease and systemic health. Braz Oral Res 2015; 29:55.
  • Rocha, J. M. D., Chaves, V. R., Urbanetz, A. A., Baldissera, R. D. S., & Rösing, C. K.. Obstetricians’ knowledge of periodontal disease as a potential risk factor for preterm delivery and low birth weight. Braz Oral Res 2011;25:248–54.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Araştırma Makaleleri
Yazarlar

Eda Çetin Özdemir 0000-0001-5792-304X

Meral Uzunkaya 0000-0001-7605-6527

Proje Numarası yok
Erken Görünüm Tarihi 28 Mart 2024
Yayımlanma Tarihi 28 Mart 2024
Gönderilme Tarihi 27 Kasım 2023
Kabul Tarihi 5 Şubat 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 19 Sayı: 1

Kaynak Göster

AMA Çetin Özdemir E, Uzunkaya M. Evaluation of The Awareness of Medical Practitioners About Drug-Induced Gingival Enlargement: A Preliminary Study. KSÜ Tıp Fak Der. Mart 2024;19(1):128-133. doi:10.17517/ksutfd.1396757