Araştırma Makalesi
Yıl 2017,
Cilt: 76 Sayı: 2, 57 - 60, 27.12.2017
Öz
Kaynakça
- 1. Boath AS, Stewart D, McDougall GJ. Berry components inhibit α-glucosidase in vitro: Synergies between acarbose and polyphenols from black currant and rowanberry. Food Chem 2012; 135(3): 929-36. 2. Beidokhti MN, Jäger AK. Review of antidiabetic fruits, vegetables, beverages, oils and spices commonly consumed in the diet. J Ethnopharmacol 2017; 201: 26-41. 3. Kahn SE, Cooper ME, Del Prato S. Pathophysiology and treatment of type 2 diabetes: Perspectives on the past, present, and future. Lancet 2014; 383(9922): 1068-83. 4. Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc 2014; 64(4): 474-6. 5. Dehghan H, Sarrafi Y, Salehi P. Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran. J Food Drug Anal 2016; 24(1): 179-88. 6. Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2009; 2(5): 270-8. 7. Olszewska M. Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. J Pharmaceut Biomed 2008; 48(3): 629-35. 8. Baytop T. Therapy with Medicinal Plants in Turkey (Past and Present). Istanbul: Nobel Tip Kitabevleri Press; 1999. 9. Termentzi A, Kefalas P, Kokkalou E. LC-DAD-MS (ESI+) analysis of the phenolic content of Sorbus domestica fruits in relation to their maturity stage. Food Chem 2008; 106(3): 1234-45. 10. Fotakis C, Tsigrimani D, Tsiaka T, Lantzouraki DZ, Strati IF, Makris C, et al. Metabolic and antioxidant profiles of herbal infusions and decoctions. Food Chem 2016; 211: 963-71. 11. Bothon FT, Debiton E, Avlessi F, Forestier C, Teulade JC, Sohounhloue DK. In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine. BMC Complem Altern M 2013; 13(1): 51 (open access). 12. Ali H, Houghton PJ, Soumyanath A. α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol 2006; 107(3): 449-55. 13. Slinkard K, Singleton VL. Total phenol analysis: automation and comparison with manual methods. Am J Enol Viticult 1977; 28(1): 49-55. 14. Kim DO, Chun OK, Kim YJ, Moon HY, Lee CY. Quantification of polyphenolics and their antioxidant capacity in fresh plums. J Agr Food Chem 2003; 51(22): 6509-15. 15. Ogbole OO, Aliu LO, Abiodun OO, Ajaiyeoba EO. Alpha-amylase inhibition and brine shrimp lethality activities of nine medicinal plant extracts from South-West Nigerian ethnomedicine. J Herbs Spices Med Plants 2016; 22(4): 319-26. 16. Grussu D, Stewart D, McDougall GJ. Berry polyphenols inhibit α-amylase in vitro: identifying active components in rowanberry and raspberry. J Agr Food Chem 2011; 59(6): 2324-31. 17. Vianna R, Brault A, Martineau LC, Couture R, Arnason JT, Haddad PS. In vivo anti-diabetic activity of the ethanolic crude extract of Sorbus decora CK Schneid. (Rosacea): A medicinal plant used by Canadian James Bay Cree nations to treat symptoms related to diabetes. Evid Based Complement Alternat Med 2011; 2011: 237941. 18. Li L, Su X, Tang H. Hypoglycemic effects of the n-butanol part of Sorbus tianschanica. Medicinal Plant 2014; 5(5): 1-2. 19. Tiwari AK, Rao JM. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr Sci 2002; 83(1): 30-8. 20. Dembinska-Kiec A, Mykkänen O, Kiec-Wilk B, Mykkänen H. Antioxidant phytochemicals against type 2 diabetes. Br J Nutr 2008; 99(E-S1), ES109-ES117. 21. Olszewska MA, Michel P. Antioxidant activity of inflorescences, leaves and fruits of three Sorbus species in relation to their polyphenolic composition. Nat Prod Res 2009; 23(16): 1507-21. 22. Mrkonjić ZO, Nađpal J, Beara I, Sabo VA, Četojević-Simin D, Mimica-Dukić N, et al. Phenolic profiling and bioactivities of fresh fruits and jam of Sorbus species. J Serb Chem Soc 2017; 82(6): 651-64.
Yıl 2017,
Cilt: 76 Sayı: 2, 57 - 60, 27.12.2017
Öz
Fruits
of several Sorbus species (Rosaceace) are used both in traditional medicine as
antidiabetic, antiinflammatory, diuretic, vasoprotective and in foods. In this
study, in vitro antidiabetic activities of water extracts of Sorbus aucuparia
L. (rowan tree) and Sorbus torminalis L. Crantz (wild sevice tree) fruits were
investigated by measuring inhibitory potentials on α-glucosidase and pancreatic
α-amylase activities, the most important digestive enzymes. Also, the total
phenolic and flavonoid contents of the fruits were determined to evaluate the
association between phenolic content and antidiabetic activity. S. torminalis and
S. aucuparia extracts exhibited strong α-glucosidase inhibitory activity, more
effective than that of standard drug acarbose. However, S. torminalis has shown
moderate inhibitory effect against α-amylase while S. aucuparia exhibited weak
inhibition. The total phenolic and flavonoid contents of the fruits were
correlated with andiabetic activities. It has been suggested that antidiabetic
effects of the fruits may be due to phenolic compounds present therein.
Therefore, S. aucuparia and S. torminalis fruits might be potential sources of
antidiabetic compounds.
Anahtar Kelimeler
: Sorbus aucuparia Sorbus torminalis antidiabetic activity α-amylase α-glucosidase
Kaynakça
- 1. Boath AS, Stewart D, McDougall GJ. Berry components inhibit α-glucosidase in vitro: Synergies between acarbose and polyphenols from black currant and rowanberry. Food Chem 2012; 135(3): 929-36. 2. Beidokhti MN, Jäger AK. Review of antidiabetic fruits, vegetables, beverages, oils and spices commonly consumed in the diet. J Ethnopharmacol 2017; 201: 26-41. 3. Kahn SE, Cooper ME, Del Prato S. Pathophysiology and treatment of type 2 diabetes: Perspectives on the past, present, and future. Lancet 2014; 383(9922): 1068-83. 4. Kalra S. Alpha glucosidase inhibitors. J Pak Med Assoc 2014; 64(4): 474-6. 5. Dehghan H, Sarrafi Y, Salehi P. Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran. J Food Drug Anal 2016; 24(1): 179-88. 6. Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2009; 2(5): 270-8. 7. Olszewska M. Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species. J Pharmaceut Biomed 2008; 48(3): 629-35. 8. Baytop T. Therapy with Medicinal Plants in Turkey (Past and Present). Istanbul: Nobel Tip Kitabevleri Press; 1999. 9. Termentzi A, Kefalas P, Kokkalou E. LC-DAD-MS (ESI+) analysis of the phenolic content of Sorbus domestica fruits in relation to their maturity stage. Food Chem 2008; 106(3): 1234-45. 10. Fotakis C, Tsigrimani D, Tsiaka T, Lantzouraki DZ, Strati IF, Makris C, et al. Metabolic and antioxidant profiles of herbal infusions and decoctions. Food Chem 2016; 211: 963-71. 11. Bothon FT, Debiton E, Avlessi F, Forestier C, Teulade JC, Sohounhloue DK. In vitro biological effects of two anti-diabetic medicinal plants used in Benin as folk medicine. BMC Complem Altern M 2013; 13(1): 51 (open access). 12. Ali H, Houghton PJ, Soumyanath A. α-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. J Ethnopharmacol 2006; 107(3): 449-55. 13. Slinkard K, Singleton VL. Total phenol analysis: automation and comparison with manual methods. Am J Enol Viticult 1977; 28(1): 49-55. 14. Kim DO, Chun OK, Kim YJ, Moon HY, Lee CY. Quantification of polyphenolics and their antioxidant capacity in fresh plums. J Agr Food Chem 2003; 51(22): 6509-15. 15. Ogbole OO, Aliu LO, Abiodun OO, Ajaiyeoba EO. Alpha-amylase inhibition and brine shrimp lethality activities of nine medicinal plant extracts from South-West Nigerian ethnomedicine. J Herbs Spices Med Plants 2016; 22(4): 319-26. 16. Grussu D, Stewart D, McDougall GJ. Berry polyphenols inhibit α-amylase in vitro: identifying active components in rowanberry and raspberry. J Agr Food Chem 2011; 59(6): 2324-31. 17. Vianna R, Brault A, Martineau LC, Couture R, Arnason JT, Haddad PS. In vivo anti-diabetic activity of the ethanolic crude extract of Sorbus decora CK Schneid. (Rosacea): A medicinal plant used by Canadian James Bay Cree nations to treat symptoms related to diabetes. Evid Based Complement Alternat Med 2011; 2011: 237941. 18. Li L, Su X, Tang H. Hypoglycemic effects of the n-butanol part of Sorbus tianschanica. Medicinal Plant 2014; 5(5): 1-2. 19. Tiwari AK, Rao JM. Diabetes mellitus and multiple therapeutic approaches of phytochemicals: Present status and future prospects. Curr Sci 2002; 83(1): 30-8. 20. Dembinska-Kiec A, Mykkänen O, Kiec-Wilk B, Mykkänen H. Antioxidant phytochemicals against type 2 diabetes. Br J Nutr 2008; 99(E-S1), ES109-ES117. 21. Olszewska MA, Michel P. Antioxidant activity of inflorescences, leaves and fruits of three Sorbus species in relation to their polyphenolic composition. Nat Prod Res 2009; 23(16): 1507-21. 22. Mrkonjić ZO, Nađpal J, Beara I, Sabo VA, Četojević-Simin D, Mimica-Dukić N, et al. Phenolic profiling and bioactivities of fresh fruits and jam of Sorbus species. J Serb Chem Soc 2017; 82(6): 651-64.
Toplam 1 adet kaynakça vardır.
Ayrıntılar
| Bölüm | Araştırma Makaleleri |
|---|---|
| Yazarlar | |
| Yayımlanma Tarihi | 27 Aralık 2017 |
| Gönderilme Tarihi | 17 Ekim 2017 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 76 Sayı: 2 |
