Review
BibTex RIS Cite

ANIMAL STUDIES IN FIELD OF PERIODONTOLOGY: EXPERIMENTAL PERIODONTAL AND PERIIMPLANT DISEASE INDUCTION

Year 2017, Volume: 20 Issue: 1, 62 - 71, 11.05.2017

Hatice Balcı Yuce

https://doi.org/10.7126/cumudj.307312
Cited By: 1

Abstract

Preclinical
studies are crucial in studying the etiology and pathogenesis of human diseases
especially diseases with multifactoriel etiology such as diabetes,
cardiovascular diseases and periodontitis. Studies in animal models are
complementary to in vitro experiments prior to clinical trials. Every model has
its own advantage and disadvantage and there is not any model suitable for all
kinds of studies. To find the optimal experimental model and animal species is
a major issue for researchers. In this mini-review I aimed to review the animal
models used in the field of periodontology and a relatively novel field
implantology and though very little, to provide guidance for researchers

Keywords

Experimental model animal study animal model

References

  • Referans1. Wakeman AJ. On the Hexon Bases of Liver Tissue under Normal and Certain Pathological Conditions. The Journal of experimental medicine 1905;7:292-304.
  • Referans2. Sognnaes R. Experimental production of periodontal disease in animals fed on a purified, nutritionally adequate diet. Journal of dental research 1947;26:475.
  • Referans3. Weinberg MA, Bral M. Laboratory animal models in periodontology. Journal of clinical periodontology 1999;26:335-340.
  • Referans4. Socransky SS, Hubersak C, Propas D. Induction of periodontal destruction in gnotobiotic rats by a human oral strain of Actinomyces naeslundii. Archives of oral biology 1970;15:993-995.
  • Referans5. Kuhr A, Popa-Wagner A, Schmoll H, Schwahn C, Kocher T. Observations on experimental marginal periodontitis in rats. Journal of periodontal research 2004;39:101-106.
  • Referans6. Rovin S, Costich ER, Gordon HA. The influence of bacteria and irritation in the initiation of periodontal disease in germfree and conventional rats. Journal of periodontal research 1966;1:193-204.
  • Referans7. Baker PJ, Evans RT, Roopenian DC. Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice. Archives of oral biology 1994;39:1035-1040.
  • Referans8. Lalla E, Lamster IB, Feit M, Huang L, Schmidt AM. A murine model of accelerated periodontal disease in diabetes. Journal of periodontal research 1998;33:387-399.
  • Referans9. Garlet GP, Cardoso CR, Silva TA, et al. Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors. Oral microbiology and immunology 2006;21:12-20.
  • Referans10. Sharma A, Inagaki S, Honma K, Sfintescu C, Baker PJ, Evans RT. Tannerella forsythia-induced alveolar bone loss in mice involves leucine-rich-repeat BspA protein. Journal of dental research 2005;84:462-467.
  • Referans11. Lee SF, Andrian E, Rowland E, Marquez IC. Immune response and alveolar bone resorption in a mouse model of Treponema denticola infection. Infection and immunity 2009;77:694-698.
  • Referans12. Leonard EP. Periodontitis. Animal model: periodontitis in the rice rat (Oryzomys palustris). The American journal of pathology 1979;96:643-646.
  • Referans13. Graves DT, Kang J, Andriankaja O, Wada K, Rossa C, Jr. Animal models to study host-bacteria interactions involved in periodontitis. Frontiers of oral biology 2012;15:117-132.
  • Referans14. Boyce BF, Aufdemorte TB, Garrett IR, Yates AJ, Mundy GR. Effects of interleukin-1 on bone turnover in normal mice. Endocrinology 1989;125:1142-1150.
  • Referans15. Li L, Khansari A, Shapira L, Graves DT, Amar S. Contribution of interleukin-11 and prostaglandin(s) in lipopolysaccharide-induced bone resorption in vivo. Infection and immunity 2002;70:3915-3922.
  • Referans16. Sandberg E, Dahlin C, Linde A. Bone regeneration by the osteopromotion technique using bioabsorbable membranes: an experimental study in rats. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1993;51:1106-1114.
  • Referans17. Hirota M, Matsui Y, Mizuki N, et al. Combination with allogenic bone reduces early absorption of beta-tricalcium phosphate (beta-TCP) and enhances the role as a bone regeneration scaffold. Experimental animal study in rat mandibular bone defects. Dental materials journal 2009;28:153-161.
  • Referans18. Deppe H, Stemberger A, Hillemanns M. Effects of osteopromotive and anti-infective membranes on bone regeneration: an experimental study in rat mandibular defects. The International journal of oral & maxillofacial implants 2003;18:369-376.
  • Referans19. Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plastic and reconstructive surgery 1988;81:672-676.
  • Referans20. Miller WA, Ripley JF. Early periodontal disease in the Syrian hamster. Journal of periodontology 1975;46:368-374.
  • Referans21. Lallam-Laroye C, Escartin Q, Zlowodzki AS, et al. Periodontitis destructions are restored by synthetic glycosaminoglycan mimetic. Journal of biomedical materials research Part A 2006;79:675-683.
  • Referans22. Keyes PH, Jordan HV. Periodontal Lesions in the Syrian Hamster. Iii. Findings Related to an Infectious and Transmissible Component. Archives of oral biology 1964;9:377-400.
  • Referans23. Baron R, Saffar JL. A quantitative study of bone remodeling during experimental periodontal disease in the golden hamster. Journal of periodontal research 1978;13:309-315.
  • Referans24. Struillou X, Boutigny H, Soueidan A, Layrolle P. Experimental animal models in periodontology: a review. The open dentistry journal 2010;4:37-47.
  • Referans25. Schmitt JM, Buck DC, Joh SP, Lynch SE, Hollinger JO. Comparison of porous bone mineral and biologically active glass in critical-sized defects. Journal of periodontology 1997;68:1043-1053.
  • Referans26. Johnson MW, Sullivan SM, Rohrer M, Collier M. Regeneration of peri-implant infrabony defects using PerioGlas: a pilot study in rabbits. The International journal of oral&maxillofacial implants 1997;12:835-839.
  • Referans27. Hasturk H, Kantarci A, Ebrahimi N, et al. Topical H2 antagonist prevents periodontitis in a rabbit model. Infection and immunity 2006; 74:2402-2414.
  • Referans28. Hasturk H, Jones VL, Andry C, Kantarci A. 1-Tetradecanol complex reduces progression of Porphyromonas gingivalis-induced experimental periodontitis in rabbits. Journal of periodontology 2007;78:924-932.
  • Referans29. Listgarten MA, Johnson D, Nowotny A, Tanner AC, Socransky SS. Histopathology of periodontal disease in gnotobiotic rats monoinfected with Eikenella corrodens. Journal of periodontal research 1978;13:134-148.
  • Referans30. King JD, Gimson AP. Experimental investigations of parodontal disease in the ferret and related lesions in man. British dental journal 1947;83:126; passim.
  • Referans31. Harper DS, Mann PH, Regnier S. Measurement of dietary and dentifrice effects upon calculus accumulation rates in the domestic ferret. Journal of dental research 1990;69:447-450.
  • Referans32. Mann PH, Harper DS, Regnier S. Reduction of calculus accumulation in domestic ferrets with two dentifrices containing pyrophosphate. Journal of dental research 1990;69:451-453.
  • Referans33. Pavlica Z, Petelin M, Nemec A, Erzen D, Skaleric U. Measurement of total antioxidant capacity in gingival crevicular fluid and serum in dogs with periodontal disease. American journal of veterinary research 2004;65:1584-1588.
  • Referans34. Niemiec BA. Periodontal disease. Topics in companion animal medicine 2008;23:72-80.
  • Referans35. Oz HS, Puleo DA. Animal models for periodontal disease. Journal of biomedicine & biotechnology 2011;2011:754857.
  • Referans36. Hamp SE, Lindhe J, Loe H. Experimental periodontitis in the beagle dog. Journal of periodontal research 1972:13-14.
  • Referans37. Albuquerque C, Morinha F, Requicha J, et al. Canine periodontitis: the dog as an important model for periodontal studies. Vet J 2012;191:299-305.
  • Referans38. Kalkwarf KL, Krejci RF. Effect of inflammation on periodontal attachment levels in miniature swine with mucogingival defects. Journal of periodontology 1983;54:361-364.
  • Referans39. Singh G, O'Neal RB, Brennan WA, Strong SL, Horner JA, Van Dyke TE. Surgical treatment of induced peri-implantitis in the micro pig: clinical and histological analysis. Journal of periodontology 1993;64:984-989.
  • Referans40. Liu Y, Zheng Y, Ding G, et al. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells 2008;26:1065-1073.
  • Referans41. Wang S, Liu Y, Fang D, Shi S. The miniature pig: a useful large animal model for dental and orofacial research. Oral diseases 2007;13:530-537.
  • Referans42. Schou S, Holmstrup P, Kornman KS. Non-human primates used in studies of periodontal disease pathogenesis: a review of the literature. Journal of periodontology 1993;64:497-508.
  • Referans43. Sculean A, Donos N, Brecx M, Reich E, Karring T. Treatment of intrabony defects with guided tissue regeneration and enamel-matrix-proteins. An experimental study in monkeys. Journal of clinical periodontology 2000; 27:466-472.
  • Referans44. Lang NP, Berglundh T. Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology. Journal of clinical periodontology 2011;38 Suppl 11:178-181.
  • Referans45. Schwarz F, Sculean A, Engebretson SP, Becker J, Sager M. Animal models for peri-implant mucositis and peri-implantitis. Periodontology 2000 2015;68:168-181.
  • Referans46. Lindhe J, Berglundh T, Ericsson I, Liljenberg B, Marinello C. Experimental breakdown of peri-implant and periodontal tissues. A study in the beagle dog. Clinical oral implants research 1992;3:9-16.
  • Referans47. Pearce AI, Richards RG, Milz S, Schneider E, Pearce SG. Animal models for implant biomaterial research in bone: a review. European cells & materials 2007;13:1-10.
  • Referans48. Schwarz F, Jepsen S, Herten M, Sager M, Rothamel D, Becker J. Influence of different treatment approaches on non-submerged and submerged healing of ligature induced peri-implantitis lesions: an experimental study in dogs. Journal of clinical periodontology 2006; 33:584-595.
  • Referans49. Levin L, Zigdon H, Coelho PG, Suzuki M, Machtei EE. Reimplantation of dental implants following ligature-induced peri-implantitis: a pilot study in dogs. Clinical implant dentistry and related research 2013;15:1-6.
  • Referans50. Hickey JS, O'Neal RB, Scheidt MJ, Strong SL, Turgeon D, Van Dyke TE. Microbiologic characterization of ligature-induced peri-implantitis in the microswine model. Journal of periodontology 1991;62:548-553.
  • Referans51. Freire MO, Sedghizadeh PP, Schaudinn C, et al. Development of an animal model for Aggregatibacter actinomycetemcomitans biofilm- mediated oral osteolytic infection: a preliminary study. Journal of periodontology 2011;82:778-789.
  • Referans52. Harmankaya N, Igawa K, Stenlund P, Palmquist A, Tengvall P. Healing of complement activating Ti implants compared with non-activating Ti in rat tibia. Acta biomaterialia 2012;8:3532-3540.
  • Referans53. Shen LH, Meng LN, Wang X, Jiang H, Wang SS. [Establishment of animal model with peri-implantitis after immediate implantation in rabbits]. Shanghai kou qiang yi xue=Shanghai journal of stomatology 2015;24:37-40.
  • Referans54. Wancket LM. Animal Models for Evaluation of Bone Implants and Devices: Comparative Bone Structure and Common Model Uses. Veterinary pathology 2015;52: 842-850.
  • Referans55. Nguyen Vo TN, Hao J, Chou J, et al. Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model. Clinical oral implants research 2016.
  • Referans56. Machado MA, Stefani CM, Sallum EA, Sallum AW, Tramontina VA, Nociti Junior FH. Treatment of ligature-induced peri-implantitis defects by regenerative procedures: a clinical study in dogs. Journal of oral science 1999;41:181-185.
  • Referans57. Martins O, Ramos JC, Baptista IP, Dard MM. The dog as a model for peri-implantitis: A review. Journal of investigative surgery : the official journal of the Academy of Surgical Research 2014;27:50-56.
  • Referans58. Albouy JP, Abrahamsson I, Berglundh T. Spontaneous progression of experimental peri-implantitis at implants with different surface characteristics: an experimental study in dogs. Journal of clinical periodontology 2012;39:182-187.
  • Referans59. Kozlovsky A, Tal H, Laufer BZ, et al. Impact of implant overloading on the peri-implant bone in inflamed and non-inflamed peri-implant mucosa. Clinical oral implants research 2007;18:601-610.
  • Referans60. Parvu AE, Talu S, Taulescu MA, et al. Fractal analysis of ibuprofen effect on experimental dog peri-implantitis. Implant dentistry 2014;23:295-304.
  • Referans61. Guo M, Wang Z, Fan X, et al. kgp, rgpA, and rgpB DNA vaccines induce antibody responses in experimental peri-implantitis. Journal of periodontology 2014;85:1575-1581.
  • Referans62. Mueller CK, Thorwarth M, Schultze-Mosgau S. Analysis of inflammatory periimplant lesions during a 12-week period of undisturbed plaque accumulation--a comparison between flapless and flap surgery in the mini-pig. Clinical oral investigations 2012;16:379-385.
  • Referans63. Sun P, Wang J, Zheng Y, Fan Y, Gu Z. BMP2/7 heterodimer is a stronger inducer of bone regeneration in peri-implant bone defects model than BMP2 or BMP7 homodimer. Dental materials journal 2012;31:239-248.
  • Referans64. Park SY, Kim KH, Rhee SH, et al. An immediate peri-implantitis induction model to study regenerative peri-implantitis treatments. Clinical oral implants research 2015.
  • Referans65. Becker ST, Foge M, Beck-Broichsitter BE, et al. Induction of periimplantitis in dental implants. The Journal of craniofacial surgery 2013;24:e15-18.
  • Referans66. Pirih FQ, Hiyari S, Barroso AD, et al. Ligature- induced peri-implantitis in mice. Journal of periodontal research 2015;50:519-524.
  • Referans67. Freire MO, Devaraj A, Young A, et al. A Bacterial Biofilm Induced Oral Osteolytic Infection Can be Successfully Treated by Immuno-Targeting an Extracellular Nucleoid Associated Protein. Molecular oral microbiology 2016.

Periodontoloji Alanında Hayvan Çalışmaları: Deneysel Periodontal ve Periimplant Hastalığın İndüksiyonu

Year 2017, Volume: 20 Issue: 1, 62 - 71, 11.05.2017

Hatice Balcı Yuce

https://doi.org/10.7126/cumudj.307312
Cited By: 1

Abstract

Preklinik araştırmalar,
özellikle diyabet, kardiyovasküler hastalıklar ve periodontitis gibi
multifaktoriyel etiyolojiye sahip insan hastalıklarının etiyoloji ve
patogenezinin araştırılması için oldukça önemlidir. Hayvan modellerinde yapılan
araştırmalar, in vitro deneylerle birlikte klinik araştırmalardan önce
gerçekleştirilmelidir. Her deney modelinin kendine özgü avantaj ve dezavantajı
bulunmaktadır ve hiçbir model, tüm araştırma konularının hepsi için tek başına
elverişli değildir. En uygun deneysel modeli ve hayvan türünü belirleyebilmek,
araştırıcılar için zor bir durumdur. Bu mini derlemede, Periodontoloji alanında
ve nispeten daha yeni bir alan olan İmplantoloji alanında kullanılan hayvan
modellerinin derlenmesi ve çok az da olsa, araştırıcılara rehber olabilmek
amaçlanmıştır.

Keywords

Deneysel araştırmalar Hayvan çalışmaları Hayvan modelleri

References

  • Referans1. Wakeman AJ. On the Hexon Bases of Liver Tissue under Normal and Certain Pathological Conditions. The Journal of experimental medicine 1905;7:292-304.
  • Referans2. Sognnaes R. Experimental production of periodontal disease in animals fed on a purified, nutritionally adequate diet. Journal of dental research 1947;26:475.
  • Referans3. Weinberg MA, Bral M. Laboratory animal models in periodontology. Journal of clinical periodontology 1999;26:335-340.
  • Referans4. Socransky SS, Hubersak C, Propas D. Induction of periodontal destruction in gnotobiotic rats by a human oral strain of Actinomyces naeslundii. Archives of oral biology 1970;15:993-995.
  • Referans5. Kuhr A, Popa-Wagner A, Schmoll H, Schwahn C, Kocher T. Observations on experimental marginal periodontitis in rats. Journal of periodontal research 2004;39:101-106.
  • Referans6. Rovin S, Costich ER, Gordon HA. The influence of bacteria and irritation in the initiation of periodontal disease in germfree and conventional rats. Journal of periodontal research 1966;1:193-204.
  • Referans7. Baker PJ, Evans RT, Roopenian DC. Oral infection with Porphyromonas gingivalis and induced alveolar bone loss in immunocompetent and severe combined immunodeficient mice. Archives of oral biology 1994;39:1035-1040.
  • Referans8. Lalla E, Lamster IB, Feit M, Huang L, Schmidt AM. A murine model of accelerated periodontal disease in diabetes. Journal of periodontal research 1998;33:387-399.
  • Referans9. Garlet GP, Cardoso CR, Silva TA, et al. Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors. Oral microbiology and immunology 2006;21:12-20.
  • Referans10. Sharma A, Inagaki S, Honma K, Sfintescu C, Baker PJ, Evans RT. Tannerella forsythia-induced alveolar bone loss in mice involves leucine-rich-repeat BspA protein. Journal of dental research 2005;84:462-467.
  • Referans11. Lee SF, Andrian E, Rowland E, Marquez IC. Immune response and alveolar bone resorption in a mouse model of Treponema denticola infection. Infection and immunity 2009;77:694-698.
  • Referans12. Leonard EP. Periodontitis. Animal model: periodontitis in the rice rat (Oryzomys palustris). The American journal of pathology 1979;96:643-646.
  • Referans13. Graves DT, Kang J, Andriankaja O, Wada K, Rossa C, Jr. Animal models to study host-bacteria interactions involved in periodontitis. Frontiers of oral biology 2012;15:117-132.
  • Referans14. Boyce BF, Aufdemorte TB, Garrett IR, Yates AJ, Mundy GR. Effects of interleukin-1 on bone turnover in normal mice. Endocrinology 1989;125:1142-1150.
  • Referans15. Li L, Khansari A, Shapira L, Graves DT, Amar S. Contribution of interleukin-11 and prostaglandin(s) in lipopolysaccharide-induced bone resorption in vivo. Infection and immunity 2002;70:3915-3922.
  • Referans16. Sandberg E, Dahlin C, Linde A. Bone regeneration by the osteopromotion technique using bioabsorbable membranes: an experimental study in rats. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 1993;51:1106-1114.
  • Referans17. Hirota M, Matsui Y, Mizuki N, et al. Combination with allogenic bone reduces early absorption of beta-tricalcium phosphate (beta-TCP) and enhances the role as a bone regeneration scaffold. Experimental animal study in rat mandibular bone defects. Dental materials journal 2009;28:153-161.
  • Referans18. Deppe H, Stemberger A, Hillemanns M. Effects of osteopromotive and anti-infective membranes on bone regeneration: an experimental study in rat mandibular defects. The International journal of oral & maxillofacial implants 2003;18:369-376.
  • Referans19. Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plastic and reconstructive surgery 1988;81:672-676.
  • Referans20. Miller WA, Ripley JF. Early periodontal disease in the Syrian hamster. Journal of periodontology 1975;46:368-374.
  • Referans21. Lallam-Laroye C, Escartin Q, Zlowodzki AS, et al. Periodontitis destructions are restored by synthetic glycosaminoglycan mimetic. Journal of biomedical materials research Part A 2006;79:675-683.
  • Referans22. Keyes PH, Jordan HV. Periodontal Lesions in the Syrian Hamster. Iii. Findings Related to an Infectious and Transmissible Component. Archives of oral biology 1964;9:377-400.
  • Referans23. Baron R, Saffar JL. A quantitative study of bone remodeling during experimental periodontal disease in the golden hamster. Journal of periodontal research 1978;13:309-315.
  • Referans24. Struillou X, Boutigny H, Soueidan A, Layrolle P. Experimental animal models in periodontology: a review. The open dentistry journal 2010;4:37-47.
  • Referans25. Schmitt JM, Buck DC, Joh SP, Lynch SE, Hollinger JO. Comparison of porous bone mineral and biologically active glass in critical-sized defects. Journal of periodontology 1997;68:1043-1053.
  • Referans26. Johnson MW, Sullivan SM, Rohrer M, Collier M. Regeneration of peri-implant infrabony defects using PerioGlas: a pilot study in rabbits. The International journal of oral&maxillofacial implants 1997;12:835-839.
  • Referans27. Hasturk H, Kantarci A, Ebrahimi N, et al. Topical H2 antagonist prevents periodontitis in a rabbit model. Infection and immunity 2006; 74:2402-2414.
  • Referans28. Hasturk H, Jones VL, Andry C, Kantarci A. 1-Tetradecanol complex reduces progression of Porphyromonas gingivalis-induced experimental periodontitis in rabbits. Journal of periodontology 2007;78:924-932.
  • Referans29. Listgarten MA, Johnson D, Nowotny A, Tanner AC, Socransky SS. Histopathology of periodontal disease in gnotobiotic rats monoinfected with Eikenella corrodens. Journal of periodontal research 1978;13:134-148.
  • Referans30. King JD, Gimson AP. Experimental investigations of parodontal disease in the ferret and related lesions in man. British dental journal 1947;83:126; passim.
  • Referans31. Harper DS, Mann PH, Regnier S. Measurement of dietary and dentifrice effects upon calculus accumulation rates in the domestic ferret. Journal of dental research 1990;69:447-450.
  • Referans32. Mann PH, Harper DS, Regnier S. Reduction of calculus accumulation in domestic ferrets with two dentifrices containing pyrophosphate. Journal of dental research 1990;69:451-453.
  • Referans33. Pavlica Z, Petelin M, Nemec A, Erzen D, Skaleric U. Measurement of total antioxidant capacity in gingival crevicular fluid and serum in dogs with periodontal disease. American journal of veterinary research 2004;65:1584-1588.
  • Referans34. Niemiec BA. Periodontal disease. Topics in companion animal medicine 2008;23:72-80.
  • Referans35. Oz HS, Puleo DA. Animal models for periodontal disease. Journal of biomedicine & biotechnology 2011;2011:754857.
  • Referans36. Hamp SE, Lindhe J, Loe H. Experimental periodontitis in the beagle dog. Journal of periodontal research 1972:13-14.
  • Referans37. Albuquerque C, Morinha F, Requicha J, et al. Canine periodontitis: the dog as an important model for periodontal studies. Vet J 2012;191:299-305.
  • Referans38. Kalkwarf KL, Krejci RF. Effect of inflammation on periodontal attachment levels in miniature swine with mucogingival defects. Journal of periodontology 1983;54:361-364.
  • Referans39. Singh G, O'Neal RB, Brennan WA, Strong SL, Horner JA, Van Dyke TE. Surgical treatment of induced peri-implantitis in the micro pig: clinical and histological analysis. Journal of periodontology 1993;64:984-989.
  • Referans40. Liu Y, Zheng Y, Ding G, et al. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells 2008;26:1065-1073.
  • Referans41. Wang S, Liu Y, Fang D, Shi S. The miniature pig: a useful large animal model for dental and orofacial research. Oral diseases 2007;13:530-537.
  • Referans42. Schou S, Holmstrup P, Kornman KS. Non-human primates used in studies of periodontal disease pathogenesis: a review of the literature. Journal of periodontology 1993;64:497-508.
  • Referans43. Sculean A, Donos N, Brecx M, Reich E, Karring T. Treatment of intrabony defects with guided tissue regeneration and enamel-matrix-proteins. An experimental study in monkeys. Journal of clinical periodontology 2000; 27:466-472.
  • Referans44. Lang NP, Berglundh T. Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology. Journal of clinical periodontology 2011;38 Suppl 11:178-181.
  • Referans45. Schwarz F, Sculean A, Engebretson SP, Becker J, Sager M. Animal models for peri-implant mucositis and peri-implantitis. Periodontology 2000 2015;68:168-181.
  • Referans46. Lindhe J, Berglundh T, Ericsson I, Liljenberg B, Marinello C. Experimental breakdown of peri-implant and periodontal tissues. A study in the beagle dog. Clinical oral implants research 1992;3:9-16.
  • Referans47. Pearce AI, Richards RG, Milz S, Schneider E, Pearce SG. Animal models for implant biomaterial research in bone: a review. European cells & materials 2007;13:1-10.
  • Referans48. Schwarz F, Jepsen S, Herten M, Sager M, Rothamel D, Becker J. Influence of different treatment approaches on non-submerged and submerged healing of ligature induced peri-implantitis lesions: an experimental study in dogs. Journal of clinical periodontology 2006; 33:584-595.
  • Referans49. Levin L, Zigdon H, Coelho PG, Suzuki M, Machtei EE. Reimplantation of dental implants following ligature-induced peri-implantitis: a pilot study in dogs. Clinical implant dentistry and related research 2013;15:1-6.
  • Referans50. Hickey JS, O'Neal RB, Scheidt MJ, Strong SL, Turgeon D, Van Dyke TE. Microbiologic characterization of ligature-induced peri-implantitis in the microswine model. Journal of periodontology 1991;62:548-553.
  • Referans51. Freire MO, Sedghizadeh PP, Schaudinn C, et al. Development of an animal model for Aggregatibacter actinomycetemcomitans biofilm- mediated oral osteolytic infection: a preliminary study. Journal of periodontology 2011;82:778-789.
  • Referans52. Harmankaya N, Igawa K, Stenlund P, Palmquist A, Tengvall P. Healing of complement activating Ti implants compared with non-activating Ti in rat tibia. Acta biomaterialia 2012;8:3532-3540.
  • Referans53. Shen LH, Meng LN, Wang X, Jiang H, Wang SS. [Establishment of animal model with peri-implantitis after immediate implantation in rabbits]. Shanghai kou qiang yi xue=Shanghai journal of stomatology 2015;24:37-40.
  • Referans54. Wancket LM. Animal Models for Evaluation of Bone Implants and Devices: Comparative Bone Structure and Common Model Uses. Veterinary pathology 2015;52: 842-850.
  • Referans55. Nguyen Vo TN, Hao J, Chou J, et al. Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model. Clinical oral implants research 2016.
  • Referans56. Machado MA, Stefani CM, Sallum EA, Sallum AW, Tramontina VA, Nociti Junior FH. Treatment of ligature-induced peri-implantitis defects by regenerative procedures: a clinical study in dogs. Journal of oral science 1999;41:181-185.
  • Referans57. Martins O, Ramos JC, Baptista IP, Dard MM. The dog as a model for peri-implantitis: A review. Journal of investigative surgery : the official journal of the Academy of Surgical Research 2014;27:50-56.
  • Referans58. Albouy JP, Abrahamsson I, Berglundh T. Spontaneous progression of experimental peri-implantitis at implants with different surface characteristics: an experimental study in dogs. Journal of clinical periodontology 2012;39:182-187.
  • Referans59. Kozlovsky A, Tal H, Laufer BZ, et al. Impact of implant overloading on the peri-implant bone in inflamed and non-inflamed peri-implant mucosa. Clinical oral implants research 2007;18:601-610.
  • Referans60. Parvu AE, Talu S, Taulescu MA, et al. Fractal analysis of ibuprofen effect on experimental dog peri-implantitis. Implant dentistry 2014;23:295-304.
  • Referans61. Guo M, Wang Z, Fan X, et al. kgp, rgpA, and rgpB DNA vaccines induce antibody responses in experimental peri-implantitis. Journal of periodontology 2014;85:1575-1581.
  • Referans62. Mueller CK, Thorwarth M, Schultze-Mosgau S. Analysis of inflammatory periimplant lesions during a 12-week period of undisturbed plaque accumulation--a comparison between flapless and flap surgery in the mini-pig. Clinical oral investigations 2012;16:379-385.
  • Referans63. Sun P, Wang J, Zheng Y, Fan Y, Gu Z. BMP2/7 heterodimer is a stronger inducer of bone regeneration in peri-implant bone defects model than BMP2 or BMP7 homodimer. Dental materials journal 2012;31:239-248.
  • Referans64. Park SY, Kim KH, Rhee SH, et al. An immediate peri-implantitis induction model to study regenerative peri-implantitis treatments. Clinical oral implants research 2015.
  • Referans65. Becker ST, Foge M, Beck-Broichsitter BE, et al. Induction of periimplantitis in dental implants. The Journal of craniofacial surgery 2013;24:e15-18.
  • Referans66. Pirih FQ, Hiyari S, Barroso AD, et al. Ligature- induced peri-implantitis in mice. Journal of periodontal research 2015;50:519-524.
  • Referans67. Freire MO, Devaraj A, Young A, et al. A Bacterial Biofilm Induced Oral Osteolytic Infection Can be Successfully Treated by Immuno-Targeting an Extracellular Nucleoid Associated Protein. Molecular oral microbiology 2016.
There are 67 citations in total.

Details

Subjects Health Care Administration
Journal Section Review
Authors

Hatice Balcı Yuce

Publication Date May 11, 2017
Submission Date April 20, 2017
Published in Issue Year 2017Volume: 20 Issue: 1

Cite

EndNote Balcı Yuce H (May 1, 2017) ANIMAL STUDIES IN FIELD OF PERIODONTOLOGY: EXPERIMENTAL PERIODONTAL AND PERIIMPLANT DISEASE INDUCTION. Cumhuriyet Dental Journal 20 1 62–71.

Cited By

Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations
Biomedicines
Shahla Mirzaeei
https://doi.org/10.3390/biomedicines9080975
 Download Cover Image

Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.


CDJ accepts articles in English. Submitting a paper to CDJ is free of charges. In addition, CDJ has not have article processing charges.

Frequency: Four times a year (March, June, September, and December)

IMPORTANT NOTICE

All users of Cumhuriyet Dental Journal should visit to their user's home page through the "https://dergipark.org.tr/tr/user" " or "https://dergipark.org.tr/en/user" links to update their incomplete information shown in blue or yellow warnings and update their e-mail addresses and information to the DergiPark system. Otherwise, the e-mails from the journal will not be seen or fall into the SPAM folder. Please fill in all missing part in the relevant field.

Please visit journal's AUTHOR GUIDELINE to see revised policy and submission rules to be held since 2020.