Abstract
Periodontitis is an inflammatory mechanism causing step by step destruction of the periodontal tissues and alveolar bone. Periodontal treatment is intended to restore the tissues damaged by the disease. Various periodontal procedures have been introduced to lower the destruction; statins are being one among them. They are cholesterol-reducing drugs which have shown to promote bone formation and proven to be effective in periodontal therapy. However, statins have numerous actions, with anti-inflammatory and immunomodulatory effects, as well as the capacity to accelerate new bone formation. The pleiotropic effects of statins have been assessed for their prospective advantage in the therapy of several inflammatory and immune-mediated diseases including periodontitis. Such features could be beneficial for periodontal therapies. This article goes through the history and effects of statins and explores its potential role in periodontal regenerative therapy.
References
- Goodson JM, Cugini MA, Kent RL, Armitage GC, Cobb CM, Fine D, et al. Multicenter evaluation of tetracycline fiber therapy: I. Experimental design, methods, and baseline data. J Periodont Res 1991a; 26:361-70.
Abstract
References
- Goodson JM, Cugini MA, Kent RL, Armitage GC, Cobb CM, Fine D, et al. Multicenter evaluation of tetracycline fiber therapy: I. Experimental design, methods, and baseline data. J Periodont Res 1991a; 26:361-70.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Review |
| Authors | |
| Publication Date | June 30, 2022 |
| Submission Date | October 8, 2021 |
| Published in Issue | Year 2022 |
Cited By
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Research Journal of Pharmacy and Technology
https://doi.org/10.52711/0974-360X.2023.00444
Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.
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