Review
BibTex RIS Cite

Tat Genlerinin Diş Çürüğüne Etkisi

Year 2022, Volume: 9 Issue: 3, 968 - 976, 26.12.2022
https://doi.org/10.15311/selcukdentj.1057033

Abstract

Diş çürüklerinin oluşumunda birçok faktör etkili olmasına rağmen önlenebilen bir hastalıktır. Tat genleri de bu etkili faktörler rasında yer almakta olup diş çürüğünün başlıca nedenlerinden biri olan şeker alımında etkili olduğu bilinmektedir. Tat reseptörlerini ifade eden genlerdeki polimorfizmler ile diş çürükleri arasında ilişki olduğu belirlenmiştir. Çocuğun doğumdan önceki yaşamında annenin tükettiği besinlerin, bebeklerin gelecekteki beslenme tercihlerini etkilediği görülmektedir. Aynı şekilde bebekliğin ilk yıllarında tüketilen besinler de bireylerin ilerideki beslenme seçimlerini etkilemektedir. Bazı çalışmalarda tat reseptörlerini ifade eden genlerdeki çeşitli polimorfizmlerin besin seçimleri ile ilişkili olduğu gösterilmiştir. Ayrıca birçok çalışmada TAS1R2, TAS2R38 ve GLUT2 genlerinin polimorfizmleri incelenmiş ve bu çalışmaların çoğunda tat genlerindeki çeşitli polimorfizmlerin DMF-T, dmf-t ve ICDAS değerleri ile ilişkili olduğu ortaya konmuştur. Bu gen polimorfizmlerinin bir kısmının diş çürüğü oluşumunu engellediğini, bir kısmının ise diş çürüğü oluşumuna neden olduğunu belirten çalışmalar mevcuttur. Şekerli gıdaların neden olabileceği kanser, kalp-damar hastalıkları, obezite, hiperlipidemi, hipertansiyon ve diş çürüğü gibi hastalıkların önlenmesinde de genetik faktörlerin etkili olabileceği kanıtlanmıştır. Diş çürüğü ve genetik arasındaki ilişkiyi anlamak, bu hastalığın nedenlerini belirlemeye ve hastalığı önlemek için çürük risk gruplarını değerlendirmeye ve yönetmeye yardımcı olabilir.

References

  • 1. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380:2224–60.
  • 2. Raine KD. Determinants of healthy eating in Canada: an overview and synthesis. Can J Public Health 2005; 96:S8–14, S8–
  • 3. Malik VS, Popkin BM, Bray GA, Despres JP, Willett WC, Hu FB. Sugarsweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care 2010; 33:2477–83.
  • 4. McGuire, Shelley. "World Health Organization. Comprehensive Implementation Plan On Maternal, Infant, And Young Child Nutrition. Geneva, Switzerland, 2014". Advances In Nutrition 2015; 6(1):134-135.
  • 5. Behrendt, I., and M. Krawinkel. Kinder Sollten Mehr Obst Und Gemüse Essen. Bundesgesundheitsblatt - Gesundheitsforschung – Gesundheitsschutz 2012; 55(2):254-259.
  • 6. Knai C, Pomerleau J, Lock K, Mcnee M. Getting Children To Eat More Fruit And Vegetables: A Systematic Review. Preventive Medicine 2006;42(2):85-95.
  • 7. Li Y, Argimon S, Schön C, Saraithong P, Caufield P. Characterizing Diversity Of Lactobacilli Associated With Severe Early Childhood Caries: A Study Protocol. Advances In Microbiology 2015;05(01):9-20.
  • 8. Özata F, Demirbaş K.A. Diş çürüğü ve genetik. Ege Üniversitesi Dişhekimliği Fakültesi Dergisi. 2001; 22: 13-21.
  • 9. Bachmanov A, Bosak N, Lin C, Matsumoto I, Ohmoto M, Reed D, et al. Genetics Of Taste Receptors. Current Pharmaceutical Design 2014;20(16):2669-2683.
  • 10. Chaudhari N, Roper SD. The cell biology of taste. J Cell Biol. 2010;190(3):285-96.
  • 11. Nelson G, Hoon M, Chandrashekar J, Zhang Y, Ryba N, Zucker C. Mammalian Sweet Taste Receptors. Cell 2001;106(3): 381-390.
  • 12. Li, X, Staszewski L, Xu H, Durick K, Zoller M, Adler E. Human Receptors For Sweet And Umami Taste. Proceedings Of The National Academy Of Sciences 2002;99(7):4692-4696.
  • 13. Glendinning, John I. Is The Bitter Rejection Response Always Adaptive?. Physiology & Behavior 1994;56(6):1217-1227.
  • 14. Adler E, Hoon M, Mueller K, Chandrashekar J, Ryba N, Zucker C. A Novel Family Of Mammalian Taste Receptors. Cell 2000;100(6):693-702.
  • 15. Beauchamp GK, Stein LJ. Salt Taste, The senses: A comprehensive reference. Basbaum AI, editor. Salt Taste. Elsevier; 2008. P. 401-408.
  • 16. Kellenberger, Stephan, and Laurent Schild. Epithelial Sodium Channel/Degenerin Family Of Ion Channels: A Variety Of Functions For A Shared Structure. Physiological Reviews 2002;82(3):735-767.
  • 17. Bachmanov, A. A. Positional Cloning Of The Mouse Saccharin Preference (Sac) Locus. Chemical Senses 2001;26(7):925-933.
  • 18. Nelson T, Lopezjimenez N, Tessarollo L, Inoue M, Bachmanov A, Sullivan S. Taste Function In Mice With A Targeted Mutation Of The Pkd1l3 Gene. Chemical Senses 2010;35(7):565-577.
  • 19. Ishimaru Y, Inada H, Kubota M, Zhuang H, Tominaga M, Matsunami H. Transient Receptor Potential Family Members PKD1L3 And PKD2L1 Form A Candidate Sour Taste Receptor. Proceedings Of The National Academy Of Sciences 2006;103(33):12569-12574.
  • 20. Lopezjimenez N, Sainz E, Cavenagh M, Cruz-Ithier M, Blackwood C, Battey J, et al. Two Novel Genes, Gpr113, Which Encodes A Family 2 G-Protein-Coupled Receptor, And Trcg1, Are Selectively Expressed In Taste Receptor Cells. Genomics 2005;85(4):472-482.
  • 21. Running CA, Craig BA, Mattes RD. Oleogustus: The Unique Taste of Fat. Chem Senses 2015;40(7):507-16.
  • 22. Liu D, Archer N, Duesing K, Hannan G, Keast R. Mechanism of fat taste perception: Association with diet and obesity. Prog Lipid Res 2016;63:41-9.
  • 23. Nolden AA, Feeney EL. Genetic Differences in Taste Receptors: Implications for the Food Industry. Annu Rev Food Sci Technol 2020;25(11):183-204.
  • 24. Nicklaus, Sophie. The Role Of Food Experiences During Early Childhood In Food Pleasure Learning. Appetite 2016;104:3-9.
  • 25. Wadhera D, Capaldi Philips E, Wilkie L. Teaching Children To Like And Eat Vegetables. Appetite 2015;93:75-84.
  • 26. Schwartz C, Chabanet C, Lange C, Issanchou S, Nicklaus S. The Role Of Taste In Food Acceptance At The Beginning Of Complementary Feeding. Physiology & Behavior 2011;104(4):646-652.
  • 27. Mennella JA, Nuala KB. The Sweetness And Bitterness Of Childhood: Insights From Basic Research On Taste Preferences. Physiology & Behavior 2015;152:502-507.
  • 28. Ashmead D, Reilly B, Lipsitt L. Neonates' Heart Rate, Sucking Rhythm, And Sucking Amplitude As A Function Of The Sweet Taste. Journal Of Experimental Child Psychology 1980;29(2):264-281.
  • 29. Blass, Elliott M, and Lisa B Watt. Suckling- And Sucrose-Induced Analgesia In Human Newborns. Pain 1999;83(3):611-623.
  • 30. Mennella J, Jagnow C, Beauchamp G. Prenatal And Postnatal Flavor Learning By Human Infants. PEDIATRICS 2001;107(6):e88-e88.
  • 31. Hepper P, Wells D, Dornan J, Lynch C. Long-Term Flavor Recognition In Humans With Prenatal Garlic Experience. Developmental Psychobiology 2012;55(5):568-574.
  • 32. Bartoshuk LM. Comparing sensory experiences across individuals: recent psychophysical advances illuminate genetic variation in taste perception. Chem Senses 2000;25(4):447-60.
  • 33. Tepper BJ, Banni S, Melis M, Crnjar R, Tomassini Barbarossa I. Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with physiological mechanisms controlling body mass index (BMI). Nutrients 2014;6(9):3363-81.
  • 34. Melis M, Atzori E, Cabras S, Zonza A, Calò C, Muroni P, et al. The Gustin (CA6) Gene Polymorphism, rs2274333 (A/G), as a Mechanistic Link between PROP Tasting and Fungiform Taste Papilla Density and Maintenance. PLoS ONE 2013;8(9): e74151.
  • 35. Pepino MY, Love-Gregory L, Klein S, Abumrad NA. The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res 2012;53(3):561-6.
  • 36. Stewart JE, Keast RS. Recent fat intake modulates fat taste sensitivity in lean and overweight subjects. Int J Obes (Lond) 2012;36(6):834-42.
  • 37. Diószegi J, Llanaj E, Ádány R. Genetic Background of Taste Perception, Taste Preferences, and Its Nutritional Implications: A Systematic Review. Front. Genet. 2019;10:1272.
  • 38. Bawajeeh, AO, Albar SA, Zhang H, Zulyniak MA, Evans CEL, Cade JE, Impact of Taste on Food Choices in Adolescence—Systematic Review and Meta-Analysis. Nutrients 2020;12:1985.
  • 39. Park S, Liu M, Song MY. Mental stress and physical activity interact with the genetic risk scores of the genetic variants related to sweetness preference in high sucrose-containing food and glucose tolerance. Food Sci Nutr. 2020;8(7):3492-3503.
  • 40. Zhao H, Zhou Y, Pinto C, Charles-Dominique P, Galindo-Gonzales J, Zhang S, et al. Evolution Of The Sweet Taste Receptor Gene Tas1r2 In Bats. Molecular Biology And Evolution 2010;27(11):2642-2650.
  • 41. Eny K, Wolever T, Fontaine-Bisson B, El-Sohemy A. Genetic Variant In The Glucose Transporter Type 2 Is Associated With Higher Intakes Of Sugars In Two Distinct Populations. Physiological Genomics 2008;33(3):355-360.
  • 42. Eny K, Wolever T, Corey P, El-Sohemy A. Genetic Variation In TAS1R2 (Ile191val) Is Associated With Consumption Of Sugars In Overweight And Obese Individuals In 2 Distinct Populations. The American Journal Of Clinical Nutrition 2010;92(6):1501-1510.
  • 43. Kulkarni G, Chng T, Eny K, Nielsen D, Wessman C, El-Sohemy A. Association Of GLUT2 and TAS1R2 Genotypes With Risk For Dental Caries. Caries Research 2013;47(3):219-225.
  • 44. Eriksson L, Esberg A, Haworth S, Holgerson P, Johansson I. Allelic Variation In Taste Genes Is Associated With Taste And Diet Preferences And Dental Caries. Nutrients 2019;11(7):1491.
  • 45. Izakovicova Holla L, Borilova Linhartova P, Lucanova S, Kastovsky J, Musilova K, Bartosova M, et al. GLUT2 and TAS1R2 Polymorphisms and Susceptibility to Dental Caries. Caries Research 2015;49:417–424.
  • 46. Robino A, Bevilacqua L, Piratsu N, Situlin R, Di Lenarda R, Gasparini P, et al. Polymorphisms In Sweet Taste Genes (TAS1R2 And GLUT2), Sweet Liking, And Dental Caries Prevalence In An Adult Italian Population. Genes & Nutrition 2015;10(5).
  • 47. Haznedaroglu E, Koldemir-Gündüz M, Bakır-Coşkun N, Bozkuş H, Çağatay P, Süsleyici-Duman B, et al. Association Of Sweet Taste Receptor Gene Polymorphisms With Dental Caries Experience In School Children. Caries Research 2015;49(3):275-281.
  • 48. Shimomura-Kuroki J, Nashida T, Miyagawa Y, Sekimoto T. The Role Of Genetic Factors In The Outbreak Mechanism Of Dental Caries. Journal Of Clinical Pediatric Dentistry 2018;42(1):32-36.
  • 49. Esberg A, Haworth S, Hasslöf P, Lif Holgerson P, Johansson I. Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes. Nutrients 2020;12(3):681.
  • 50. Cavallari T, Yumi Arima L, Ferrasa A, Moyses J, Moyses T, Herai R, et al. Dental Caries: Genetic And Protein Interactions. Archives Of Oral Biology 2019;108:104522.
  • 51. Chisini LA, Cademartori MG, Conde MCM, Costa FDS, Salvi LC, Tovo-Rodrigues L, et al. Single nucleotide polymorphisms of taste genes and caries: a systematic review and meta-analysis. Acta Odontol. Scand. 2021;79(2):147-155.
  • 52. Arid J, Antunes LAA, Koch LFA, Evangelista SS, Vasconcelos KRF, Brancher JA, et al. Association of taste receptor gene polymorphisms with dental caries. Braz Oral Res. 2020;34:e055.
  • 53. Işık- Çalışkan, Deniz. Park Sağlık Ocağı Bölgesindeki Bir İlkokulda Diş Çürükleri ve Etkili Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 1999;52(2):1.
  • 54. Doichinova L, Bakardjiev P, Peneva M. Assessment Of Food Habits In Children Aged 6–12 Years And The Risk Of Caries. Biotechnology & Biotechnological Equipment 2014;29(1):200-204.
  • 55. Muller-Bolla M, Courson F, Smail-Faugeron V, Bernardin T, Lupi-Pegurier L. Dental Erosion In French Adolescents. BMC Oral Health 2015;15(1).
  • 56. Nehring I, Kostka T, Von Kries R, Rehfuess E. Impacts Of In Utero And Early Infant Taste Experiences On Later Taste Acceptance: A Systematic Review. The Journal Of Nutrition 2015;145(6):1271-1279.
  • 57. Beauchamp GK, Mennella JA. Flavor Perception In Human Infants: Development And Functional Significance. Digestion 2011;83(1):1-6.
  • 58. Precone V, Beccari T, Stuppia L, Baglivo M, Paolacci S, Manara E, et al. Taste, olfactory and texture related genes and food choices: implications on health status. European Review for Medical and Pharmacological Sciences 2019;23:1305-1321.
Year 2022, Volume: 9 Issue: 3, 968 - 976, 26.12.2022
https://doi.org/10.15311/selcukdentj.1057033

Abstract

References

  • 1. Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380:2224–60.
  • 2. Raine KD. Determinants of healthy eating in Canada: an overview and synthesis. Can J Public Health 2005; 96:S8–14, S8–
  • 3. Malik VS, Popkin BM, Bray GA, Despres JP, Willett WC, Hu FB. Sugarsweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care 2010; 33:2477–83.
  • 4. McGuire, Shelley. "World Health Organization. Comprehensive Implementation Plan On Maternal, Infant, And Young Child Nutrition. Geneva, Switzerland, 2014". Advances In Nutrition 2015; 6(1):134-135.
  • 5. Behrendt, I., and M. Krawinkel. Kinder Sollten Mehr Obst Und Gemüse Essen. Bundesgesundheitsblatt - Gesundheitsforschung – Gesundheitsschutz 2012; 55(2):254-259.
  • 6. Knai C, Pomerleau J, Lock K, Mcnee M. Getting Children To Eat More Fruit And Vegetables: A Systematic Review. Preventive Medicine 2006;42(2):85-95.
  • 7. Li Y, Argimon S, Schön C, Saraithong P, Caufield P. Characterizing Diversity Of Lactobacilli Associated With Severe Early Childhood Caries: A Study Protocol. Advances In Microbiology 2015;05(01):9-20.
  • 8. Özata F, Demirbaş K.A. Diş çürüğü ve genetik. Ege Üniversitesi Dişhekimliği Fakültesi Dergisi. 2001; 22: 13-21.
  • 9. Bachmanov A, Bosak N, Lin C, Matsumoto I, Ohmoto M, Reed D, et al. Genetics Of Taste Receptors. Current Pharmaceutical Design 2014;20(16):2669-2683.
  • 10. Chaudhari N, Roper SD. The cell biology of taste. J Cell Biol. 2010;190(3):285-96.
  • 11. Nelson G, Hoon M, Chandrashekar J, Zhang Y, Ryba N, Zucker C. Mammalian Sweet Taste Receptors. Cell 2001;106(3): 381-390.
  • 12. Li, X, Staszewski L, Xu H, Durick K, Zoller M, Adler E. Human Receptors For Sweet And Umami Taste. Proceedings Of The National Academy Of Sciences 2002;99(7):4692-4696.
  • 13. Glendinning, John I. Is The Bitter Rejection Response Always Adaptive?. Physiology & Behavior 1994;56(6):1217-1227.
  • 14. Adler E, Hoon M, Mueller K, Chandrashekar J, Ryba N, Zucker C. A Novel Family Of Mammalian Taste Receptors. Cell 2000;100(6):693-702.
  • 15. Beauchamp GK, Stein LJ. Salt Taste, The senses: A comprehensive reference. Basbaum AI, editor. Salt Taste. Elsevier; 2008. P. 401-408.
  • 16. Kellenberger, Stephan, and Laurent Schild. Epithelial Sodium Channel/Degenerin Family Of Ion Channels: A Variety Of Functions For A Shared Structure. Physiological Reviews 2002;82(3):735-767.
  • 17. Bachmanov, A. A. Positional Cloning Of The Mouse Saccharin Preference (Sac) Locus. Chemical Senses 2001;26(7):925-933.
  • 18. Nelson T, Lopezjimenez N, Tessarollo L, Inoue M, Bachmanov A, Sullivan S. Taste Function In Mice With A Targeted Mutation Of The Pkd1l3 Gene. Chemical Senses 2010;35(7):565-577.
  • 19. Ishimaru Y, Inada H, Kubota M, Zhuang H, Tominaga M, Matsunami H. Transient Receptor Potential Family Members PKD1L3 And PKD2L1 Form A Candidate Sour Taste Receptor. Proceedings Of The National Academy Of Sciences 2006;103(33):12569-12574.
  • 20. Lopezjimenez N, Sainz E, Cavenagh M, Cruz-Ithier M, Blackwood C, Battey J, et al. Two Novel Genes, Gpr113, Which Encodes A Family 2 G-Protein-Coupled Receptor, And Trcg1, Are Selectively Expressed In Taste Receptor Cells. Genomics 2005;85(4):472-482.
  • 21. Running CA, Craig BA, Mattes RD. Oleogustus: The Unique Taste of Fat. Chem Senses 2015;40(7):507-16.
  • 22. Liu D, Archer N, Duesing K, Hannan G, Keast R. Mechanism of fat taste perception: Association with diet and obesity. Prog Lipid Res 2016;63:41-9.
  • 23. Nolden AA, Feeney EL. Genetic Differences in Taste Receptors: Implications for the Food Industry. Annu Rev Food Sci Technol 2020;25(11):183-204.
  • 24. Nicklaus, Sophie. The Role Of Food Experiences During Early Childhood In Food Pleasure Learning. Appetite 2016;104:3-9.
  • 25. Wadhera D, Capaldi Philips E, Wilkie L. Teaching Children To Like And Eat Vegetables. Appetite 2015;93:75-84.
  • 26. Schwartz C, Chabanet C, Lange C, Issanchou S, Nicklaus S. The Role Of Taste In Food Acceptance At The Beginning Of Complementary Feeding. Physiology & Behavior 2011;104(4):646-652.
  • 27. Mennella JA, Nuala KB. The Sweetness And Bitterness Of Childhood: Insights From Basic Research On Taste Preferences. Physiology & Behavior 2015;152:502-507.
  • 28. Ashmead D, Reilly B, Lipsitt L. Neonates' Heart Rate, Sucking Rhythm, And Sucking Amplitude As A Function Of The Sweet Taste. Journal Of Experimental Child Psychology 1980;29(2):264-281.
  • 29. Blass, Elliott M, and Lisa B Watt. Suckling- And Sucrose-Induced Analgesia In Human Newborns. Pain 1999;83(3):611-623.
  • 30. Mennella J, Jagnow C, Beauchamp G. Prenatal And Postnatal Flavor Learning By Human Infants. PEDIATRICS 2001;107(6):e88-e88.
  • 31. Hepper P, Wells D, Dornan J, Lynch C. Long-Term Flavor Recognition In Humans With Prenatal Garlic Experience. Developmental Psychobiology 2012;55(5):568-574.
  • 32. Bartoshuk LM. Comparing sensory experiences across individuals: recent psychophysical advances illuminate genetic variation in taste perception. Chem Senses 2000;25(4):447-60.
  • 33. Tepper BJ, Banni S, Melis M, Crnjar R, Tomassini Barbarossa I. Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with physiological mechanisms controlling body mass index (BMI). Nutrients 2014;6(9):3363-81.
  • 34. Melis M, Atzori E, Cabras S, Zonza A, Calò C, Muroni P, et al. The Gustin (CA6) Gene Polymorphism, rs2274333 (A/G), as a Mechanistic Link between PROP Tasting and Fungiform Taste Papilla Density and Maintenance. PLoS ONE 2013;8(9): e74151.
  • 35. Pepino MY, Love-Gregory L, Klein S, Abumrad NA. The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects. J Lipid Res 2012;53(3):561-6.
  • 36. Stewart JE, Keast RS. Recent fat intake modulates fat taste sensitivity in lean and overweight subjects. Int J Obes (Lond) 2012;36(6):834-42.
  • 37. Diószegi J, Llanaj E, Ádány R. Genetic Background of Taste Perception, Taste Preferences, and Its Nutritional Implications: A Systematic Review. Front. Genet. 2019;10:1272.
  • 38. Bawajeeh, AO, Albar SA, Zhang H, Zulyniak MA, Evans CEL, Cade JE, Impact of Taste on Food Choices in Adolescence—Systematic Review and Meta-Analysis. Nutrients 2020;12:1985.
  • 39. Park S, Liu M, Song MY. Mental stress and physical activity interact with the genetic risk scores of the genetic variants related to sweetness preference in high sucrose-containing food and glucose tolerance. Food Sci Nutr. 2020;8(7):3492-3503.
  • 40. Zhao H, Zhou Y, Pinto C, Charles-Dominique P, Galindo-Gonzales J, Zhang S, et al. Evolution Of The Sweet Taste Receptor Gene Tas1r2 In Bats. Molecular Biology And Evolution 2010;27(11):2642-2650.
  • 41. Eny K, Wolever T, Fontaine-Bisson B, El-Sohemy A. Genetic Variant In The Glucose Transporter Type 2 Is Associated With Higher Intakes Of Sugars In Two Distinct Populations. Physiological Genomics 2008;33(3):355-360.
  • 42. Eny K, Wolever T, Corey P, El-Sohemy A. Genetic Variation In TAS1R2 (Ile191val) Is Associated With Consumption Of Sugars In Overweight And Obese Individuals In 2 Distinct Populations. The American Journal Of Clinical Nutrition 2010;92(6):1501-1510.
  • 43. Kulkarni G, Chng T, Eny K, Nielsen D, Wessman C, El-Sohemy A. Association Of GLUT2 and TAS1R2 Genotypes With Risk For Dental Caries. Caries Research 2013;47(3):219-225.
  • 44. Eriksson L, Esberg A, Haworth S, Holgerson P, Johansson I. Allelic Variation In Taste Genes Is Associated With Taste And Diet Preferences And Dental Caries. Nutrients 2019;11(7):1491.
  • 45. Izakovicova Holla L, Borilova Linhartova P, Lucanova S, Kastovsky J, Musilova K, Bartosova M, et al. GLUT2 and TAS1R2 Polymorphisms and Susceptibility to Dental Caries. Caries Research 2015;49:417–424.
  • 46. Robino A, Bevilacqua L, Piratsu N, Situlin R, Di Lenarda R, Gasparini P, et al. Polymorphisms In Sweet Taste Genes (TAS1R2 And GLUT2), Sweet Liking, And Dental Caries Prevalence In An Adult Italian Population. Genes & Nutrition 2015;10(5).
  • 47. Haznedaroglu E, Koldemir-Gündüz M, Bakır-Coşkun N, Bozkuş H, Çağatay P, Süsleyici-Duman B, et al. Association Of Sweet Taste Receptor Gene Polymorphisms With Dental Caries Experience In School Children. Caries Research 2015;49(3):275-281.
  • 48. Shimomura-Kuroki J, Nashida T, Miyagawa Y, Sekimoto T. The Role Of Genetic Factors In The Outbreak Mechanism Of Dental Caries. Journal Of Clinical Pediatric Dentistry 2018;42(1):32-36.
  • 49. Esberg A, Haworth S, Hasslöf P, Lif Holgerson P, Johansson I. Oral Microbiota Profile Associates with Sugar Intake and Taste Preference Genes. Nutrients 2020;12(3):681.
  • 50. Cavallari T, Yumi Arima L, Ferrasa A, Moyses J, Moyses T, Herai R, et al. Dental Caries: Genetic And Protein Interactions. Archives Of Oral Biology 2019;108:104522.
  • 51. Chisini LA, Cademartori MG, Conde MCM, Costa FDS, Salvi LC, Tovo-Rodrigues L, et al. Single nucleotide polymorphisms of taste genes and caries: a systematic review and meta-analysis. Acta Odontol. Scand. 2021;79(2):147-155.
  • 52. Arid J, Antunes LAA, Koch LFA, Evangelista SS, Vasconcelos KRF, Brancher JA, et al. Association of taste receptor gene polymorphisms with dental caries. Braz Oral Res. 2020;34:e055.
  • 53. Işık- Çalışkan, Deniz. Park Sağlık Ocağı Bölgesindeki Bir İlkokulda Diş Çürükleri ve Etkili Faktörler. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 1999;52(2):1.
  • 54. Doichinova L, Bakardjiev P, Peneva M. Assessment Of Food Habits In Children Aged 6–12 Years And The Risk Of Caries. Biotechnology & Biotechnological Equipment 2014;29(1):200-204.
  • 55. Muller-Bolla M, Courson F, Smail-Faugeron V, Bernardin T, Lupi-Pegurier L. Dental Erosion In French Adolescents. BMC Oral Health 2015;15(1).
  • 56. Nehring I, Kostka T, Von Kries R, Rehfuess E. Impacts Of In Utero And Early Infant Taste Experiences On Later Taste Acceptance: A Systematic Review. The Journal Of Nutrition 2015;145(6):1271-1279.
  • 57. Beauchamp GK, Mennella JA. Flavor Perception In Human Infants: Development And Functional Significance. Digestion 2011;83(1):1-6.
  • 58. Precone V, Beccari T, Stuppia L, Baglivo M, Paolacci S, Manara E, et al. Taste, olfactory and texture related genes and food choices: implications on health status. European Review for Medical and Pharmacological Sciences 2019;23:1305-1321.
There are 58 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Review
Authors

Seçil Özkurt 0000-0002-9780-0383

Figen Seymen 0000-0001-7010-2035

Publication Date December 26, 2022
Submission Date February 1, 2022
Published in Issue Year 2022 Volume: 9 Issue: 3

Cite

Vancouver Özkurt S, Seymen F. Tat Genlerinin Diş Çürüğüne Etkisi. Selcuk Dent J. 2022;9(3):968-76.