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Numb Chin Syndrome: A Sign of Lung Adenocarcinoma

Year 2021, Volume: 12 Issue: 1, 120 - 123, 30.04.2021

Abstract

Objective: Numb chin syndrome (NCS), which is a sensory neuropathy and also known as mental neuropathy, is characterized by paresthesia or decreased sensation in lower lip, gingiva and oral mucosa. This condition is regarded as worrisome because it may be associated with malignancies.
Case: A 34-year-old female patient referred to the clinic with complaint of paresthesia in right lower lip. A lytic lesion involving the inferior alveolar nerve was detected on radiographic examination. Biopsy was done under local anesthesia. After the histopathological examination of the sample the diagnosis of adenocarcinoma was made. The patient was then referred to the department of oncology. As a result of the examinations, it was found that the primary cause was lung adenocarcinoma.
Conclusion: This case report emphasizes that patients with NCS should be evaluated very carefully because this condition may be a symptom of a systemic malignancy.

References

  • 1. Bruyn RP, Boogerd W. The numb chin. Clin Neurol Neurosurg. 1991;93(3):187-93.
  • 2. Colella G, Giudice A, Siniscalchi G, Falcone U, Guastafierro S. Chin numbness: a symptom that should not be underestimated: a review of 12 cases. Am J Med Sci. 2009;337(6):407-10.
  • 3. Eppley BL, Snyders RV, Jr. Mental neuropathy as a sign of distant malignancy: report of cases. J Oral Maxillofac Surg. 1992;50(10):1117-9.
  • 4. Galán Gil S, Peñarrocha Diago M, Peñarrocha Diago M. Malignant mental nerve neuropathy: systematic review. Med Oral Patol Oral Cir Bucal. 2008;13(10):E616-21.
  • 5. Aerden T, Grisar K, Neven P, Hauben E, Politis C. Numb chin syndrome as a sign of mandibular metastasis: A case report. Int J Surg Case Rep. 2017;31:68-71.
  • 6. Hirshberg A, Shnaiderman-Shapiro A, Kaplan I, Berger R. Metastatic tumours to the oral cavity - pathogenesis and analysis of 673 cases. Oral Oncol. 2008;44(8):743-52.
  • 7. Balamurugan N, Arathisenthil SV, Senthilkumaran S, Thirumalaikolundusubramanian P. Numb chin syndrome: A harbinger of tumor progression or relapse. Am J Emerg Med. 2017;35(5):805.e1-.e2.
  • 8. Hiraki A, Nakamura S, Abe K, Takenoshita Y, Horinouchi Y, Shinohara M, et al. Numb chin syndrome as an initial symptom of acute lymphocytic leukemia: report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;83(5):555-61.
  • 9. Bar-Ziv J, Slasky BS. CT imaging of mental nerve neuropathy: the numb chin syndrome. AJR Am J Roentgenol. 1997;168(2):371-6.
  • 10. Smith RM, Hassan A, Robertson CE. Numb Chin Syndrome. Curr Pain Headache Rep. 2015;19(9):44.

Uyuşuk Çene Sendromu: Akciğer Adenokarsinomunun Bir İşareti

Year 2021, Volume: 12 Issue: 1, 120 - 123, 30.04.2021

Abstract

Amaç: Duyusal bir nöropati olan ve kaybı zamanda mental nöropati olarak da bilinen uyuşuk çene sendromu (UÇS), alt dudak, diş eti ve ağız mukozasında parestezi ya da his kaybı ile karakterizedir. Bu durum, malignitelerle ilişkili olabileceğinden endişe verici olarak kabul edilmektedir.
Olgu:34 yaşında kadın hasta sağ alt dudakta parestezi şikayeti ile kliniğe başvurdu. Radyografik incelemede inferior alveolar siniri içine alan bir litik lezyon tespit edildi. Lokal anestezi altında biyopsi yapıldı. Örneğin histopatolojik incelemesinin ardından adenokarsinom tanısı konuldu. Hasta daha sonra onkoloji bölümüne yönlendirildi. İncelemeler sonucunda birincil nedenin akciğer adenokarsinomu olduğu tespit edildi.
Sonuç: Bu vaka raporu UÇS’li hastaların çok dikkatli değerlendirilmesi gerektiğini vurgulamaktır çünkü bu durum bir sistemik malignitenin belirtisi olabilmektedir.

References

  • 1. Bruyn RP, Boogerd W. The numb chin. Clin Neurol Neurosurg. 1991;93(3):187-93.
  • 2. Colella G, Giudice A, Siniscalchi G, Falcone U, Guastafierro S. Chin numbness: a symptom that should not be underestimated: a review of 12 cases. Am J Med Sci. 2009;337(6):407-10.
  • 3. Eppley BL, Snyders RV, Jr. Mental neuropathy as a sign of distant malignancy: report of cases. J Oral Maxillofac Surg. 1992;50(10):1117-9.
  • 4. Galán Gil S, Peñarrocha Diago M, Peñarrocha Diago M. Malignant mental nerve neuropathy: systematic review. Med Oral Patol Oral Cir Bucal. 2008;13(10):E616-21.
  • 5. Aerden T, Grisar K, Neven P, Hauben E, Politis C. Numb chin syndrome as a sign of mandibular metastasis: A case report. Int J Surg Case Rep. 2017;31:68-71.
  • 6. Hirshberg A, Shnaiderman-Shapiro A, Kaplan I, Berger R. Metastatic tumours to the oral cavity - pathogenesis and analysis of 673 cases. Oral Oncol. 2008;44(8):743-52.
  • 7. Balamurugan N, Arathisenthil SV, Senthilkumaran S, Thirumalaikolundusubramanian P. Numb chin syndrome: A harbinger of tumor progression or relapse. Am J Emerg Med. 2017;35(5):805.e1-.e2.
  • 8. Hiraki A, Nakamura S, Abe K, Takenoshita Y, Horinouchi Y, Shinohara M, et al. Numb chin syndrome as an initial symptom of acute lymphocytic leukemia: report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;83(5):555-61.
  • 9. Bar-Ziv J, Slasky BS. CT imaging of mental nerve neuropathy: the numb chin syndrome. AJR Am J Roentgenol. 1997;168(2):371-6.
  • 10. Smith RM, Hassan A, Robertson CE. Numb Chin Syndrome. Curr Pain Headache Rep. 2015;19(9):44.
There are 10 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Olgu Sunumları
Authors

Hüseyin Gülcan 0000-0003-3811-1710

Uğur Gülşen 0000-0003-1282-2936

Publication Date April 30, 2021
Submission Date December 19, 2020
Published in Issue Year 2021 Volume: 12 Issue: 1

Cite

Vancouver Gülcan H, Gülşen U. Numb Chin Syndrome: A Sign of Lung Adenocarcinoma. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi. 2021;12(1):120-3.

SDÜ Sağlık Bilimleri Dergisi, makalenin gönderilmesi ve yayınlanması dahil olmak üzere hiçbir aşamada herhangi bir ücret talep etmemektedir. Dergimiz, bilimsel araştırmaları okuyucuya ücretsiz sunmanın bilginin küresel paylaşımını artıracağı ilkesini benimseyerek, içeriğine anında açık erişim sağlamaktadır.