Comparison of Clinical and Radiographic Healing of Periapical Lesions Using MTA or Conventional Filling Materials: Randomized Controlled Clinical Trial
Abstract
Objectives The aim of this study was to compare the effect of MTA versus conventional filling materials on the healing of teeth with periapical lesions.
Materials and methods Sixty-four teeth with periapical lesions of greater than 5 mm were divided into two groups; G1) MTA (ProRoot MTA; Dentsply Maillefer, Ballaigues, Switzerland) filling, G2) conventional filling materials (n = 32/group). In MTA group, the apical portion of the root canal was filled with ProRoot MTA and the middle and coronal thirds of the root canal were filled with injectable thermoplasticized gutta-percha system. Patients were followed for 15 months. The data were statistically analyzed with Mann-Whitney U and chi-square test (P = 0.05).
Results With a follow-up rate of 89.06% of all patients for 15 months, favorable outcomes were obtained in 100% in ProRoot MTA and 83.3% in conventional technique. (P < 0.05).
Conclusions ProRoot MTA showed better results compared to conventional filling materials in teeth with periapical radiolucency.
References
- 1. Block RM, Bushell A, Rodrigues H, Langeland K. A histopathologic, histobacteriologic, and radiographic study of periapical endodontic surgical specimens. Oral Surg Oral Med Oral Pathol 1976;42(5):656-678.
- 2. Weiner S, McKinney Jr RV, Walton RE. Characterization of the periapical surgical specimen: A morphologic and histochemical study of the inflammatory patterns. Oral Surg Oral Med Oral Pathol 1982;53(3):293-302.
- 3. Estrela C, Guedes OA, Rabelo LEG, Decurcio DA, Alencar AHG, Estrela CR, et al. Detection of apical inflammatory root resorption associated with periapical lesion using different methods. Braz Dental J 2014;25(5):404-408.
- 4. Alsulaimani RS. Single-visit endodontic treatment of mature teeth with chronic apical abscesses using mineral trioxide aggregate cement: a randomized clinical trial. BMC Oral Health 2016;16(1):1-10.
- 5. Salamat K, Rezai RF. Nonsurgical treatment of extraoral lesions caused by necrotic nonvital tooth. Oral Surg Oral Med Oral Pathol 1986;61(6):618-623.
- 6. ØRstavik D. Materials used for root canal filing: technical, biological and clinical testing. Endodontic topics 2005;12(1):25-38.
- 7. Agrafioti A, Tzimpoulas N, Chatzitheodoridis E, Kontakiotis EG. Comparative evaluation of sealing ability and microstructure of MTA and Biodentine after exposure to different environments. Clin Oral Investig 2016;20(7):1535-1540.
- 8. Torabinejad M, Parirokh M. Mineral trioxide aggregate: a comprehensive literature review—part II: leakage and biocompatibility investigations. J Endod 2010;36(2):190-202.
- 9. Fava L, Saunders W. Calcium hydroxide pastes: classification and clinical indications. Int Endod J 1999;32(4):257-282.
- 10. Moore A, Howley MF, O’Connell AC. Treatment of open apex teeth using two types of white mineral trioxide aggregate after initial dressing with calcium hydroxide in children. Dent Traumatol 2011;27(3):166-173.
- 11. Ørstavik D, Kerekes K, Eriksen HM. The periapical index: a scoring system for radiographic assessment of apical periodontitis. Dent Traumatol 1986;2(1):20-34.
- 12. Arslan H, Ahmed HMA, Şahin Y, Yıldız ED, Gündoğdu EC, Güven Y, et al. Regenerative endodontic procedures in necrotic mature teeth with periapical radiolucencies: a preliminary randomized clinical study. J Endod 2019;45(7):863-872.
- 13. Ricucci D, Russo J, Rutberg M, Burleson JA, Spångberg LS . A prospective cohort study of endodontic treatments of 1,369 root canals: results after 5 years. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112(6):825-842.
- 14. Dorasani G, Madhusudhana K, Chinni SK. Clinical and radiographic evaluation of single-visit and multi-visit endodontic treatment of teeth with periapical pathology: An in vivo study. J Conserv Dent 2013;16(6):484.
- 15. Saoud TMA, Huang GT-J, Gibbs JL, Sigurdsson A, Lin LM. Management of teeth with persistent apical periodontitis after root canal treatment using regenerative endodontic therapy. J Endod 2015;41(10):1743-1748.
- 16. Saini HR, Tewari S, Sangwan P, Duhan J, Gupta A. Effect of different apical preparation sizes on outcome of primary endodontic treatment: a randomized controlled trial. J Endod 2012;38(10):1309-1315.
- 17. Qin H, Cai J, Fang J, Xu H, Gong Y. Could MTA be a novel medicine on the recurrence therapy for GCTB? Med Hypotheses 2010;74(2):368-369.
- 18. Min K-S, Yang S-H, Kim E-C. The combined effect of mineral trioxide aggregate and enamel matrix derivative on odontoblastic differentiation in human dental pulp cells. J Endod 2009;35(6):847-851.
- 19. Maeda T, Suzuki A, Yuzawa S, Baba Y, Kimura Y, Kato Y. Mineral trioxide aggregate induces osteoblastogenesis via Atf6. Bone Rep 2015;2:36-43.
- 20. Sisli SN, Ozbas H. Comparative micro–computed tomographic evaluation of the sealing quality of ProRoot MTA and MTA Angelus apical plugs placed with various techniques. J Endod 2017;43(1):147-151.
- 21. Boutsioukis C, Noula G, Lambrianidis T. Ex vivo study of the efficiency of two techniques for the removal of mineral trioxide aggregate used as a root canal filling material. J Endod 2008;34(10):1239-1242.
Abstract
References
- 1. Block RM, Bushell A, Rodrigues H, Langeland K. A histopathologic, histobacteriologic, and radiographic study of periapical endodontic surgical specimens. Oral Surg Oral Med Oral Pathol 1976;42(5):656-678.
- 2. Weiner S, McKinney Jr RV, Walton RE. Characterization of the periapical surgical specimen: A morphologic and histochemical study of the inflammatory patterns. Oral Surg Oral Med Oral Pathol 1982;53(3):293-302.
- 3. Estrela C, Guedes OA, Rabelo LEG, Decurcio DA, Alencar AHG, Estrela CR, et al. Detection of apical inflammatory root resorption associated with periapical lesion using different methods. Braz Dental J 2014;25(5):404-408.
- 4. Alsulaimani RS. Single-visit endodontic treatment of mature teeth with chronic apical abscesses using mineral trioxide aggregate cement: a randomized clinical trial. BMC Oral Health 2016;16(1):1-10.
- 5. Salamat K, Rezai RF. Nonsurgical treatment of extraoral lesions caused by necrotic nonvital tooth. Oral Surg Oral Med Oral Pathol 1986;61(6):618-623.
- 6. ØRstavik D. Materials used for root canal filing: technical, biological and clinical testing. Endodontic topics 2005;12(1):25-38.
- 7. Agrafioti A, Tzimpoulas N, Chatzitheodoridis E, Kontakiotis EG. Comparative evaluation of sealing ability and microstructure of MTA and Biodentine after exposure to different environments. Clin Oral Investig 2016;20(7):1535-1540.
- 8. Torabinejad M, Parirokh M. Mineral trioxide aggregate: a comprehensive literature review—part II: leakage and biocompatibility investigations. J Endod 2010;36(2):190-202.
- 9. Fava L, Saunders W. Calcium hydroxide pastes: classification and clinical indications. Int Endod J 1999;32(4):257-282.
- 10. Moore A, Howley MF, O’Connell AC. Treatment of open apex teeth using two types of white mineral trioxide aggregate after initial dressing with calcium hydroxide in children. Dent Traumatol 2011;27(3):166-173.
- 11. Ørstavik D, Kerekes K, Eriksen HM. The periapical index: a scoring system for radiographic assessment of apical periodontitis. Dent Traumatol 1986;2(1):20-34.
- 12. Arslan H, Ahmed HMA, Şahin Y, Yıldız ED, Gündoğdu EC, Güven Y, et al. Regenerative endodontic procedures in necrotic mature teeth with periapical radiolucencies: a preliminary randomized clinical study. J Endod 2019;45(7):863-872.
- 13. Ricucci D, Russo J, Rutberg M, Burleson JA, Spångberg LS . A prospective cohort study of endodontic treatments of 1,369 root canals: results after 5 years. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112(6):825-842.
- 14. Dorasani G, Madhusudhana K, Chinni SK. Clinical and radiographic evaluation of single-visit and multi-visit endodontic treatment of teeth with periapical pathology: An in vivo study. J Conserv Dent 2013;16(6):484.
- 15. Saoud TMA, Huang GT-J, Gibbs JL, Sigurdsson A, Lin LM. Management of teeth with persistent apical periodontitis after root canal treatment using regenerative endodontic therapy. J Endod 2015;41(10):1743-1748.
- 16. Saini HR, Tewari S, Sangwan P, Duhan J, Gupta A. Effect of different apical preparation sizes on outcome of primary endodontic treatment: a randomized controlled trial. J Endod 2012;38(10):1309-1315.
- 17. Qin H, Cai J, Fang J, Xu H, Gong Y. Could MTA be a novel medicine on the recurrence therapy for GCTB? Med Hypotheses 2010;74(2):368-369.
- 18. Min K-S, Yang S-H, Kim E-C. The combined effect of mineral trioxide aggregate and enamel matrix derivative on odontoblastic differentiation in human dental pulp cells. J Endod 2009;35(6):847-851.
- 19. Maeda T, Suzuki A, Yuzawa S, Baba Y, Kimura Y, Kato Y. Mineral trioxide aggregate induces osteoblastogenesis via Atf6. Bone Rep 2015;2:36-43.
- 20. Sisli SN, Ozbas H. Comparative micro–computed tomographic evaluation of the sealing quality of ProRoot MTA and MTA Angelus apical plugs placed with various techniques. J Endod 2017;43(1):147-151.
- 21. Boutsioukis C, Noula G, Lambrianidis T. Ex vivo study of the efficiency of two techniques for the removal of mineral trioxide aggregate used as a root canal filling material. J Endod 2008;34(10):1239-1242.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Original Research Articles |
| Authors | |
| Publication Date | February 16, 2024 |
| Submission Date | November 3, 2022 |
| Published in Issue | Year 2024Volume: 27 Issue: 1 |
Cumhuriyet Dental Journal (Cumhuriyet Dent J, CDJ) is the official publication of Cumhuriyet University Faculty of Dentistry. CDJ is an international journal dedicated to the latest advancement of dentistry. The aim of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of dentistry. First issue of the Journal of Cumhuriyet University Faculty of Dentistry was published in 1998. In 2010, journal's name was changed as Cumhuriyet Dental Journal. Journal’s publication language is English.
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