Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study
Abstract
Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization.
Materials and Methods: Twenty-eight sound human enamel samples were randomly divided into four groups (A-D) each having seven samples as follows: A (Novamin), B (1450 ppm NaF and Novamin), C (CPP-ACP), D (1450ppm NaF). After inducing caries-like lesions, each group was maintained daily for demineralization-remineralization cycle for seven days. During this cycle, samples were treated by the selected toothpaste for each group. Enamel mineral loss was assessed by surface microhardness. Surface enamel microhardness was determined on the enamel blocks. Non-parametric Kruskar-Wallis test compares the amount of surface microhardness recovery (SMHR%) across four different toothpastes.
Results: PLM data revealed a mineral precipitation band on the surface layer of all toothpastes; however, when compared to treated lesions, no statistically significant differences among the groups (p>0.05) were found. Conclusions: NovaMin containing dentifrice has similar remineralization potential on carious-like lesions when compared to fluoride containing dentifrices.
Keywords
References
- 1. Azarpazhooh A, Main PA. Fluoride varnish in the prevention of dental caries in children and adolescents: a systematic review. J Can Dent Assoc. 2008; 74(1):73-9.
- 2. Kato MT, Leite AL, Hannas AR, Oliveira RC, Pereira JC, Tjäderhane L, Buzalaf MAR. Effect of iron on matrix metalloproteinase inhibition and on the prevention of dentine erosion. Caries Research 2010; 44(3): 309-316.
- 3. Kumar VL, Itthagarun A, King NM. The effect of casein phosphopeptide-amorphous calcium phosphate on remineralization of artificial caries-like lesions: An in vitro study. Aust Dent J 2008; 53: 34-40.
- 4. Queiroz CS, Hara AT, Paes Leme AF, Cury JA. PH cycling models to evaluate the effect of low fluoride dentifrice on enamel de- and remineralization. Braz Dent J. 2008; 19(1): 21– 7.
- 5. Peters MC, Bresciani E, Barata TJ, Fagundes TC, Navarro RL, Navarro MF, Dickens SH. In vivo dentin remineralization by calcium-phosphate cement. J Dent Res. 2010; 89 (3): 286-91.
- 6. Wiegand A, Krieger C, Attin R, Hellwig E, Attin T. Fluoride uptake and resistance to further demineralisation of demineralised enamel after application of differently concentrated acidulated sodium fluoride gels. Clin Oral Investig. 2005;9(1):52-7.
- 7. Wong MC, Clarkson J, Glenny AM, Lo EC, Marinho VC, Tsang BW, Walsh T, Worthington HV. Cochrane reviews on the benefits/risks of fluoride toothpastes. J Dent Res. 2011; 90(5): 573-9.
- 8. Passalini P, Fidalgo TK, Caldeira EM, Gleiser R, Nojima da C, Maia LC. Preventive effect of fluoridated orthodontic resins subjected to high cariogenic challenges. Braz Dent J 2010; 21(3): 211-5.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Zerrin Abbasoglu
*
Türkiye
Damla Aksit Bıçak
Türkiye
Dilara Ozenay Dergin
Türkiye
Didem Kural
Türkiye
İlknur Tanboğa
Türkiye
Publication Date
March 13, 2019
Submission Date
June 10, 2018
Acceptance Date
December 18, 2018
Published in Issue
Year 1970 Volume: 22 Number: 1
Cited By
Comparison of the Remineralization Effect of Nano Herbal Toothpaste With Two Kinds of Toothpaste Containing Fluoride and Bioactive Glass on Primary Enamel Lesions: An In Vitro Study
Avicenna Journal of Dental Research
https://doi.org/10.34172/ajdr.1736Remineralization potential of dentifrices with calcium sodium phosphosilicate and functionalized tri‐calcium phosphate in the deeper incipient carious lesions: An in vitro study
Clinical and Experimental Dental Research
https://doi.org/10.1002/cre2.876Comparative evaluation of remineralizing efficacy of calcium sodium phosphosilicate, ginger, turmeric, and fluoride
Dental Research Journal
https://doi.org/10.4103/drj.drj_32_24