Research Article
Year 2024,
Volume: 3 Issue: 1, 17 - 23, 30.04.2024
Abstract
References
- 1. Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action. J Clin Periodontol. 2017;44(5):456-62.
- 2. Madi M, Abuohashish HM, Attia D, AlQahtani N, Alrayes N, Pavlic V, et al. Association between Periodontal Disease and Comorbidities in Saudi's Eastern Province. Biomed Res Int. 2021;2021:5518195.
- 3. Rodrigues M, Barbirato D, Luiz RR, Scharfstein J, Salles GF, Feres-Filho EJ. Effect of antihypertensive therapy with angiotensin-converting enzyme inhibitors on chronic periodontitis: a case-control study. Oral Dis. 2016;22(8):791-6.
- 4. Thomas JT, Joseph B, Sorsa T, Mauramo M, Anil S, Waltimo T. Expression of advanced glycation end products and their receptors in diabetic periodontitis patients. Oral Dis. 2023.
- 5. Genco RJ, Sanz M. Clinical and public health implications of periodontal and systemic diseases: An overview. Periodontol 2000. 2020;83(1):7-13.
- 6. Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89 Suppl 1:S313-s8.
- 7. Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000. 2013;62(1):59-94.
- 8. Schliephake H. The role of systemic diseases and local conditions as risk factors. Periodontol 2000. 2022;88(1):36-51.
- 9. Hughes FJ, Bartold PM. Periodontal complications of prescription and recreational drugs. Periodontol 2000. 2018;78(1):47-58.
- 10. Wang IC, Askar H, Ghassib I, Wang CW, Wang HL. Association between periodontitis and systemic medication intake: A case-control study. J Periodontol. 2020;91(10):1245-55.
- 11. Chatzopoulos GS, Jiang Z, Marka N, Wolff LF. Relationship of Medication Intake and Systemic Conditions with Periodontitis: A Retrospective Study. J Pers Med. 2023;13(10).
- 12. Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, et al. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89 Suppl 1:S74-s84.
- 13. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol. 2018;45 Suppl 20:S149-s61.
- 14. Sezgin Y, Yilmaz M. Periodontoloji Kliniğine Başvuran Hastalarin Periodontal Durumlarinin Ve Sistemik Hastaliklarinin Değerlendirilmesi. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2019;29(3):432-9.
- 15. Eren G, Becerik S. Evaluating the Periodontal Status and Oral Hygiene Habits Among Dental Patients. Istanbul Medical Journal. 2016;17(3).
- 16. Relvas M, López-Jarana P, Monteiro L, Pacheco JJ, Braga AC, Salazar F. Study of Prevalence, Severity and Risk Factors of Periodontal Disease in a Portuguese Population. J Clin Med. 2022;11(13).
- 17. Georgiou TO, Marshall RI, Bartold PM. Prevalence of systemic diseases in Brisbane general and periodontal practice patients. Aust Dent J. 2004;49(4):177-84.
- 18. Altan G, Köse TE, Çene E, Özcan I. Bir Üniversite Hastanesi Diş Hekimliği Birimine Başvuran Hastaların Anamnez Kayıtlarının Değerlendirilmesi. Turkiye Klinikleri Journal of Dental Sciences. 2017;23(2).
- 19. Aliberti J, Viola JP, Vieira-de-Abreu A, Bozza PT, Sher A, Scharfstein J. Cutting edge: bradykinin induces IL-12 production by dendritic cells: a danger signal that drives Th1 polarization. J Immunol. 2003;170(11):5349-53.
- 20. Zheng DX, Kang XN, Wang YX, Huang YN, Pang CF, Chen YX, et al. Periodontal disease and emotional disorders: A meta-analysis. J Clin Periodontol. 2021;48(2):180-204.
- 21. Kisely S, Sawyer E, Siskind D, Lalloo R. The oral health of people with anxiety and depressive disorders - a systematic review and meta-analysis. J Affect Disord. 2016;200:119-32.
- 22. Decker AM, Kapila YL, Wang HL. The psychobiological links between chronic stress-related diseases, periodontal/peri-implant diseases, and wound healing. Periodontol 2000. 2021;87(1):94-106.
- 23. Van der Velden U. The natural history of periodontal disease: The Java study-Origin, implementation, and results 35 years on. Periodontol 2000. 2023.
- 24. Chatzopoulos GS, Tsalikis L. Periodontal treatment needs and systemic diseases in an older population in Greece. J Clin Exp Dent. 2016;8(1):e32-7.
- 25. Clark D, Kotronia E, Ramsay SE. Frailty, aging, and periodontal disease: Basic biologic considerations. Periodontol 2000. 2021;87(1):143-56.
Year 2024,
Volume: 3 Issue: 1, 17 - 23, 30.04.2024
Abstract
Amaç: Çalışmada, Akdeniz Üniversitesi Diş Hekimliği Fakültesi Periodontoloji Anabilim Dalı'na periodontal tedavi amacı ile başvuran hastalarda sistemik ilaç kullanımı ile periodontal durum arasındaki olası ilişkinin değerlendirilmesi amaçlandı.
Gereç ve Yöntem: Bu kesitsel retrospektif çalışmada hasta formlarına kaydedilmiş olan demografik, sistemik hastalık ve ilaç bilgileri, sigara kullanma durumları, günlük fırçalama alışkanlıkları ile periodontal klinik parametreleri (sondalanabilir cep derinliği, sondalamada kanama ve klinik ataçman kaybı ölçümleri) değerlendirildi. Bireylerin periodontal durumları 2017 periodontal ve periimplant hastalıklar ve durumlar sınıflandırmasına göre belirlendi.
Bulgular: Toplamda 350 kadın ve 350 erkek olmak üzere 700 hasta kaydı değerlendirildi. Katılımcıların %72’sinde gingivitis ve %.28’de periodontitis saptandı. Gingivitis ve periodontitis grupları arasında yaş (p=0,000) ve cinsiyet (p=0,000) açısından anlamlı farklılıklar vardı. Periodontitis grubunda günlük diş fırçalama alışkanlığının az olduğu (p=0.000) ancak sigara kullanma oranının yüksek olduğu bulundu (p=0.000). Bireylerin %46’sında sistemik hastalık tespit edildi ve sistemik hastalığı olan bireylerde periodontitis görülme oranı daha fazlaydı (p=0,000). Katılımcılarda en yaygın kullanılan sistemik ilaçlar; antihipertansifler (%29), oral antidiyabetikler (%13), tiroid ilaçları (%11) ve antidepresanlardır (%10). Erkeklerde antihipertansif kullanımının kadınlara oranla daha yüksek olduğu (p=0,001), kadınlarda ise bifosfonat grubu ilaç (p=0,000) kullanımının daha fazla olduğu saptandı. Lojistik regresyon analizi sonuçlarında; antihipertansif (OO=2,36; %95 GA: 1,55-3,58), antidiyabetik (OO=2,68; %95 GA: 1,58-4,53) ve antidepresan kullanımı (OO=0,39; %95 GA: 0,20-0,75), günlük diş fırçalama alışkanlığının az olması (OO=2,55; %95 GA: 1,65-3,93) ve sigara kullanımı (OO=2,62; %95 GA: 1,72-3,98) ile periodontitis arasında pozitif yönde anlamlı ilişki olduğu tespit edildi.
Sonuç: Araştırma sonuçları antihipertansifler, antidiyabetikler ve antidepresanlar gibi sistemik ilaçların kullanımı ile periodontitis arasında bir ilişki olabileceğini göstermektedir.
Supporting Institution
yoktur.
References
- 1. Tonetti MS, Jepsen S, Jin L, Otomo-Corgel J. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action. J Clin Periodontol. 2017;44(5):456-62.
- 2. Madi M, Abuohashish HM, Attia D, AlQahtani N, Alrayes N, Pavlic V, et al. Association between Periodontal Disease and Comorbidities in Saudi's Eastern Province. Biomed Res Int. 2021;2021:5518195.
- 3. Rodrigues M, Barbirato D, Luiz RR, Scharfstein J, Salles GF, Feres-Filho EJ. Effect of antihypertensive therapy with angiotensin-converting enzyme inhibitors on chronic periodontitis: a case-control study. Oral Dis. 2016;22(8):791-6.
- 4. Thomas JT, Joseph B, Sorsa T, Mauramo M, Anil S, Waltimo T. Expression of advanced glycation end products and their receptors in diabetic periodontitis patients. Oral Dis. 2023.
- 5. Genco RJ, Sanz M. Clinical and public health implications of periodontal and systemic diseases: An overview. Periodontol 2000. 2020;83(1):7-13.
- 6. Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, et al. Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89 Suppl 1:S313-s8.
- 7. Genco RJ, Borgnakke WS. Risk factors for periodontal disease. Periodontol 2000. 2013;62(1):59-94.
- 8. Schliephake H. The role of systemic diseases and local conditions as risk factors. Periodontol 2000. 2022;88(1):36-51.
- 9. Hughes FJ, Bartold PM. Periodontal complications of prescription and recreational drugs. Periodontol 2000. 2018;78(1):47-58.
- 10. Wang IC, Askar H, Ghassib I, Wang CW, Wang HL. Association between periodontitis and systemic medication intake: A case-control study. J Periodontol. 2020;91(10):1245-55.
- 11. Chatzopoulos GS, Jiang Z, Marka N, Wolff LF. Relationship of Medication Intake and Systemic Conditions with Periodontitis: A Retrospective Study. J Pers Med. 2023;13(10).
- 12. Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, et al. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89 Suppl 1:S74-s84.
- 13. Tonetti MS, Greenwell H, Kornman KS. Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol. 2018;45 Suppl 20:S149-s61.
- 14. Sezgin Y, Yilmaz M. Periodontoloji Kliniğine Başvuran Hastalarin Periodontal Durumlarinin Ve Sistemik Hastaliklarinin Değerlendirilmesi. Atatürk Üniversitesi Diş Hekimliği Fakültesi Dergisi. 2019;29(3):432-9.
- 15. Eren G, Becerik S. Evaluating the Periodontal Status and Oral Hygiene Habits Among Dental Patients. Istanbul Medical Journal. 2016;17(3).
- 16. Relvas M, López-Jarana P, Monteiro L, Pacheco JJ, Braga AC, Salazar F. Study of Prevalence, Severity and Risk Factors of Periodontal Disease in a Portuguese Population. J Clin Med. 2022;11(13).
- 17. Georgiou TO, Marshall RI, Bartold PM. Prevalence of systemic diseases in Brisbane general and periodontal practice patients. Aust Dent J. 2004;49(4):177-84.
- 18. Altan G, Köse TE, Çene E, Özcan I. Bir Üniversite Hastanesi Diş Hekimliği Birimine Başvuran Hastaların Anamnez Kayıtlarının Değerlendirilmesi. Turkiye Klinikleri Journal of Dental Sciences. 2017;23(2).
- 19. Aliberti J, Viola JP, Vieira-de-Abreu A, Bozza PT, Sher A, Scharfstein J. Cutting edge: bradykinin induces IL-12 production by dendritic cells: a danger signal that drives Th1 polarization. J Immunol. 2003;170(11):5349-53.
- 20. Zheng DX, Kang XN, Wang YX, Huang YN, Pang CF, Chen YX, et al. Periodontal disease and emotional disorders: A meta-analysis. J Clin Periodontol. 2021;48(2):180-204.
- 21. Kisely S, Sawyer E, Siskind D, Lalloo R. The oral health of people with anxiety and depressive disorders - a systematic review and meta-analysis. J Affect Disord. 2016;200:119-32.
- 22. Decker AM, Kapila YL, Wang HL. The psychobiological links between chronic stress-related diseases, periodontal/peri-implant diseases, and wound healing. Periodontol 2000. 2021;87(1):94-106.
- 23. Van der Velden U. The natural history of periodontal disease: The Java study-Origin, implementation, and results 35 years on. Periodontol 2000. 2023.
- 24. Chatzopoulos GS, Tsalikis L. Periodontal treatment needs and systemic diseases in an older population in Greece. J Clin Exp Dent. 2016;8(1):e32-7.
- 25. Clark D, Kotronia E, Ramsay SE. Frailty, aging, and periodontal disease: Basic biologic considerations. Periodontol 2000. 2021;87(1):143-56.
There are 25 citations in total.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Restorative Dentistry |
| Journal Section | Research Articles |
| Authors | |
| Publication Date | April 30, 2024 |
| Submission Date | December 20, 2023 |
| Acceptance Date | February 7, 2024 |
| Published in Issue | Year 2024 Volume: 3 Issue: 1 |
Başlangıç: 2022
Yayın Aralığı: Yılda 3 sayı
Yayıncı: Akdeniz Üniversitesi