Abstract
Supporting Institution
yok
Project Number
yok
References
- Gibbs J, Cull W, Henderson W, Daley J, Hur K, Khuri SF. Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the National VA Surgical Risk Study. Arch Surg 1999; 134: 36–42.
- Carvalho JR, Verdelho Machado M. New Insights About Albumin and Liver Disease. Ann Hepatol. 2018;17: 547-60.
- McCluskey A, Thomas AN, Bowles BJ, Kishen R. The prognostic value of serial measurements of serum albumin concentration in patients admitted to an intensive care unit. Anaesthesia 1996; 51: 724-7.
- Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. Br J Anaesth 2000; 85: 599–610
- Kim K, Seo H, Chin JH, Son HJ, Hwang JH, Kim YK. Preoperative hypoalbuminemia and anemia as predictors of transfusion in radical nephrectomy for renal cell carcinoma: a retrospective study. BMC Anesthesiol 2015; 15: 103.
- Rabie M, Negmi H, Hammad Y, Oufi H, Khalaf H. Living donor hepatectomy: comparative study between two different anesthetic techniques MEJAnesth2006; 18: 4
- Wiedermann CJ. Hypoalbuminemia as Surrogate and Culprit of Infections. Int J Mol Sci. 2021; 22: 4496
- Haskins I, Baginsky M, Amdur R, Agarwal A. Preoperative hypoalbuminemia is associated with worse outcome in colon cancer patiets. ClinNutr 2016; 12: 1-6.
- Yang P-H, Hung J-Y, Yang C-J. Successful weaning predictors in a respiratory care center in Taiwan. Kaohsiung J Med Sci 2008; 24: 85-91.
- Leite HP, Rodrigues da Silva AV, de Oliveira Iglesias SB, Koch Nogueira PC. Serum albumin is an independent predictor of clinical outcomes in critically ill children.Pediatr Crit Care Med 2016; 17: e50-7.
- Ji Q, Duan Q, Wang X, et al. Risk factors for ventilator dependency following coronary artery bypass grafting. Int J Med Sci 2012; 9: 306-10.
- Lee D, Lee R, Cross MT, Tran A, Kappa J, Moghtaderi S. Low serum albumin levels are associated with increased 30-day cardiopulmonary complications, reoperation, and readmission rates following total shoulder arthroplasty. Iowa Orthop J 2019; 39: 27-34
- Wiederman C, Wiederman W, Joannidis M. Hypoalbuminemia and acute kidney injury: a meta-analysis of observational clinical studies. Intensive care med 2010; 36: 1657-65.
- Li N, Qiao H, Guo JF, et al. Preoperative hypoalbuminemia was associated with acute kidney injury in high-risk patients following non-cardiac surgery: a retrospective cohort study. BMC Anesthesiol 2019; 19: 171.
- Sang BH, Bang JY, Song JG, Hwang GS. Hypoalbuminemia within two postoperative days is an independent risk factor for acute kidney injury following living donor liver transplantation: a propensity score analysis of 998 consecutive patients. Crit Care Med 2015; 43: 2552–61.
- Erdost H, Özkardeşler S, Akan M, et al. Comprasion of the RIFLE, AKIN and KDIGO. Diagnosticclassifications for acute renal injury in patients undergoing liver transplantation. Transplant Proc 2015; 47: 1482-7.
- Hu WH, Eisenstein S, Parry L, Ramamoorthy S. Preoperative malnutrition with mild hypoalbuminemia associated with postoperative mortality and morbidity of colorectal cancer: a propensity score matching study. Nutr J 2019; 18: 33.
- Jellinge ME, Henriksen DP, Hallas P, Brabrand M. Hypoalbuminemia is a strong predictor of 30-day all-cause mortality in acutely admitted medical patients: A prospective, observational, cohort study. PLoS One 2014; 9: e105983.
- Meyer CP, Rios-Diaz AJ, Dalela D, et al. The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures. Am J Surg 2017; 214: 871-83.
Effect of preoperative hypoalbuminemia on postoperative mortality and morbidity in liver transplant surgery
Abstract
Aim: In this study, it isaimed to retrospectively evaluatethe effect of serum albumin levels on postoperative mortality and morbidity in patients with end-stage liver failure with hypoalbuminemia who underwent follow-up liver transplant surgery.
Material and Method: After the approval of the ethics committee, the patients who underwent liver transplant surgery between April 2011 and September 2016 were divided into two groups as with preoperative albumin values <3.5 g/dl and ≥3.5 g/dl. Demographic characteristics of the patients, preoperative and postoperative arterial blood gases, posteroanterior chest radiographs, tracheal aspirate cultures, preoperative and postoperative serum creatinine levels, mechanical ventilation and intensive care unit length of stay, transfusion of blood and blood products, and early postoperative complications (30 days) were determined and compared retrospectively.
Result: It was observed that mechanical ventilation, intensive care hospitalization and discharge times were higher in the group with low albumin levels (p˂0.05). More blood and blood products were used in the group with low albumin levels (p˂0.05). Postoperative pulmonary complications and acute kidney injury were more common in the group with low albumin levels (p˂0.05). Complications in the early postoperative period were more common in the group with low albumin levels.
Conclusion: As a result, it isconcluded that the preoperative serum albumin level can be used as a guide and a valuable parameter in the postoperative follow-up in the detection of perioperative and postoperative complications in liver transplant recipients.
Project Number
yok
References
- Gibbs J, Cull W, Henderson W, Daley J, Hur K, Khuri SF. Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the National VA Surgical Risk Study. Arch Surg 1999; 134: 36–42.
- Carvalho JR, Verdelho Machado M. New Insights About Albumin and Liver Disease. Ann Hepatol. 2018;17: 547-60.
- McCluskey A, Thomas AN, Bowles BJ, Kishen R. The prognostic value of serial measurements of serum albumin concentration in patients admitted to an intensive care unit. Anaesthesia 1996; 51: 724-7.
- Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. Br J Anaesth 2000; 85: 599–610
- Kim K, Seo H, Chin JH, Son HJ, Hwang JH, Kim YK. Preoperative hypoalbuminemia and anemia as predictors of transfusion in radical nephrectomy for renal cell carcinoma: a retrospective study. BMC Anesthesiol 2015; 15: 103.
- Rabie M, Negmi H, Hammad Y, Oufi H, Khalaf H. Living donor hepatectomy: comparative study between two different anesthetic techniques MEJAnesth2006; 18: 4
- Wiedermann CJ. Hypoalbuminemia as Surrogate and Culprit of Infections. Int J Mol Sci. 2021; 22: 4496
- Haskins I, Baginsky M, Amdur R, Agarwal A. Preoperative hypoalbuminemia is associated with worse outcome in colon cancer patiets. ClinNutr 2016; 12: 1-6.
- Yang P-H, Hung J-Y, Yang C-J. Successful weaning predictors in a respiratory care center in Taiwan. Kaohsiung J Med Sci 2008; 24: 85-91.
- Leite HP, Rodrigues da Silva AV, de Oliveira Iglesias SB, Koch Nogueira PC. Serum albumin is an independent predictor of clinical outcomes in critically ill children.Pediatr Crit Care Med 2016; 17: e50-7.
- Ji Q, Duan Q, Wang X, et al. Risk factors for ventilator dependency following coronary artery bypass grafting. Int J Med Sci 2012; 9: 306-10.
- Lee D, Lee R, Cross MT, Tran A, Kappa J, Moghtaderi S. Low serum albumin levels are associated with increased 30-day cardiopulmonary complications, reoperation, and readmission rates following total shoulder arthroplasty. Iowa Orthop J 2019; 39: 27-34
- Wiederman C, Wiederman W, Joannidis M. Hypoalbuminemia and acute kidney injury: a meta-analysis of observational clinical studies. Intensive care med 2010; 36: 1657-65.
- Li N, Qiao H, Guo JF, et al. Preoperative hypoalbuminemia was associated with acute kidney injury in high-risk patients following non-cardiac surgery: a retrospective cohort study. BMC Anesthesiol 2019; 19: 171.
- Sang BH, Bang JY, Song JG, Hwang GS. Hypoalbuminemia within two postoperative days is an independent risk factor for acute kidney injury following living donor liver transplantation: a propensity score analysis of 998 consecutive patients. Crit Care Med 2015; 43: 2552–61.
- Erdost H, Özkardeşler S, Akan M, et al. Comprasion of the RIFLE, AKIN and KDIGO. Diagnosticclassifications for acute renal injury in patients undergoing liver transplantation. Transplant Proc 2015; 47: 1482-7.
- Hu WH, Eisenstein S, Parry L, Ramamoorthy S. Preoperative malnutrition with mild hypoalbuminemia associated with postoperative mortality and morbidity of colorectal cancer: a propensity score matching study. Nutr J 2019; 18: 33.
- Jellinge ME, Henriksen DP, Hallas P, Brabrand M. Hypoalbuminemia is a strong predictor of 30-day all-cause mortality in acutely admitted medical patients: A prospective, observational, cohort study. PLoS One 2014; 9: e105983.
- Meyer CP, Rios-Diaz AJ, Dalela D, et al. The association of hypoalbuminemia with early perioperative outcomes - A comprehensive assessment across 16 major procedures. Am J Surg 2017; 214: 871-83.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Research Articles |
| Authors | |
| Project Number | yok |
| Publication Date | July 26, 2022 |
| Published in Issue | Year 2022 Volume: 4 Issue: 3 |
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